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Systematic elucidation of the effective constituents and potential mechanisms of Scrophulariae Radix against neoplasm based on LC-MS, network pharmacology, and molecular docking approaches.

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Title: Systematic elucidation of the effective constituents and potential mechanisms of Scrophulariae Radix against neoplasm based on LC-MS, network pharmacology, and molecular docking approaches.
Authors: Yu SJ; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Kong XB; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Jin X; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Shan MY; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Cheng G; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Wang PL; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Li WL; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Zhao PY; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Sheng YJ; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., He BQ; Academy of Chinese Medical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Shi Q; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Li HQ; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Zhao QM; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Qin LP; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.; Zhejiang Key Laboratory of Chinese Medicine Modernization, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Meng XY; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.; Zhejiang Key Laboratory of Chinese Medicine Modernization, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Source: Frontiers in plant science [Front Plant Sci] 2025 Jul 03; Vol. 16, pp. 1615076. Date of Electronic Publication: 2025 Jul 03 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101568200 Publication Model: eCollection Cited Medium: Print ISSN: 1664-462X (Print) Linking ISSN: 1664462X NLM ISO Abbreviation: Front Plant Sci Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Yu+SJ%22">Yu SJ</searchLink>; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Kong+XB%22">Kong XB</searchLink>; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Jin+X%22">Jin X</searchLink>; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Shan+MY%22">Shan MY</searchLink>; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Cheng+G%22">Cheng G</searchLink>; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Wang+PL%22">Wang PL</searchLink>; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Li+WL%22">Li WL</searchLink>; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Zhao+PY%22">Zhao PY</searchLink>; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Sheng+YJ%22">Sheng YJ</searchLink>; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22He+BQ%22">He BQ</searchLink>; Academy of Chinese Medical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Shi+Q%22">Shi Q</searchLink>; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Li+HQ%22">Li HQ</searchLink>; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Zhao+QM%22">Zhao QM</searchLink>; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Qin+LP%22">Qin LP</searchLink>; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.; Zhejiang Key Laboratory of Chinese Medicine Modernization, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Meng+XY%22">Meng XY</searchLink>; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.; Zhejiang Key Laboratory of Chinese Medicine Modernization, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
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              Text: 2025 Jul 03
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