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Immune cell single-cell RNA sequencing analyses link an age-associated T cell subset to symptomatic benign prostatic hyperplasia.

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Title: Immune cell single-cell RNA sequencing analyses link an age-associated T cell subset to symptomatic benign prostatic hyperplasia.
Authors: Broman MM; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, United States., Lanman NA; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, United States.; Purdue Institute for Cancer Research, Purdue University, West Lafayette, IN, United States., Vickman RE; Department of Surgery, Endeavor Health formerly NorthShore University HealthSystem, Evanston, IL, United States.; Division of Urology, Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, IL, United States., Cresswell GM; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, United States., Kothandaraman H; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, United States., Kolliegbo A; Department of Computer Science, Purdue University, West Lafayette, IN, United States., Paez JSP; Purdue Institute for Cancer Research, Purdue University, West Lafayette, IN, United States.; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States., Glaser AP; Department of Surgery, Endeavor Health formerly NorthShore University HealthSystem, Evanston, IL, United States.; Division of Urology, Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, IL, United States., Helfand BT; Department of Surgery, Endeavor Health formerly NorthShore University HealthSystem, Evanston, IL, United States.; Division of Urology, Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, IL, United States., Henry G; Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, United States., Strand DW; Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, United States., Franco OE; Department of Biochemistry and Molecular Biology, Feist-Weiller Cancer Center, Louisiana State University Shreveport, Shreveport, LA, United States., Hayward SW; Department of Surgery, Endeavor Health formerly NorthShore University HealthSystem, Evanston, IL, United States.; Division of Urology, Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, IL, United States., Ratliff TL; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, United States.; Purdue Institute for Cancer Research, Purdue University, West Lafayette, IN, United States.
Source: Frontiers in immunology [Front Immunol] 2025 Jul 07; Vol. 16, pp. 1585446. Date of Electronic Publication: 2025 Jul 07 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Immune cell single-cell RNA sequencing analyses link an age-associated T cell subset to symptomatic benign prostatic hyperplasia.
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  Data: <searchLink fieldCode="AU" term="%22Broman+MM%22">Broman MM</searchLink>; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, United States.<br /><searchLink fieldCode="AU" term="%22Lanman+NA%22">Lanman NA</searchLink>; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, United States.; Purdue Institute for Cancer Research, Purdue University, West Lafayette, IN, United States.<br /><searchLink fieldCode="AU" term="%22Vickman+RE%22">Vickman RE</searchLink>; Department of Surgery, Endeavor Health formerly NorthShore University HealthSystem, Evanston, IL, United States.; Division of Urology, Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Cresswell+GM%22">Cresswell GM</searchLink>; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, United States.<br /><searchLink fieldCode="AU" term="%22Kothandaraman+H%22">Kothandaraman H</searchLink>; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, United States.<br /><searchLink fieldCode="AU" term="%22Kolliegbo+A%22">Kolliegbo A</searchLink>; Department of Computer Science, Purdue University, West Lafayette, IN, United States.<br /><searchLink fieldCode="AU" term="%22Paez+JSP%22">Paez JSP</searchLink>; Purdue Institute for Cancer Research, Purdue University, West Lafayette, IN, United States.; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States.<br /><searchLink fieldCode="AU" term="%22Glaser+AP%22">Glaser AP</searchLink>; Department of Surgery, Endeavor Health formerly NorthShore University HealthSystem, Evanston, IL, United States.; Division of Urology, Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Helfand+BT%22">Helfand BT</searchLink>; Department of Surgery, Endeavor Health formerly NorthShore University HealthSystem, Evanston, IL, United States.; Division of Urology, Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Henry+G%22">Henry G</searchLink>; Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, United States.<br /><searchLink fieldCode="AU" term="%22Strand+DW%22">Strand DW</searchLink>; Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, United States.<br /><searchLink fieldCode="AU" term="%22Franco+OE%22">Franco OE</searchLink>; Department of Biochemistry and Molecular Biology, Feist-Weiller Cancer Center, Louisiana State University Shreveport, Shreveport, LA, United States.<br /><searchLink fieldCode="AU" term="%22Hayward+SW%22">Hayward SW</searchLink>; Department of Surgery, Endeavor Health formerly NorthShore University HealthSystem, Evanston, IL, United States.; Division of Urology, Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Ratliff+TL%22">Ratliff TL</searchLink>; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, United States.; Purdue Institute for Cancer Research, Purdue University, West Lafayette, IN, United States.
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