ADAR1 haploinsufficiency and sustained picornaviral RdRp dsRNA synthesis synergize to dysregulate RNA editing and cause multi-system interferonopathy.
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| Title: | ADAR1 haploinsufficiency and sustained picornaviral RdRp dsRNA synthesis synergize to dysregulate RNA editing and cause multi-system interferonopathy. |
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| Authors: | Miller CM; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA., Morrison JH; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA., Bankers L; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA., Dran R; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA., Kendrick JM; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA., Briggs E; Department of Mechanical Engineering and BioFrontiers Institute, University of Colorado at Boulder, Boulder, Colorado, USA., Ferguson VL; Department of Mechanical Engineering and BioFrontiers Institute, University of Colorado at Boulder, Boulder, Colorado, USA., Poeschla EM; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA. |
| Source: | MBio [mBio] 2025 Aug 13; Vol. 16 (8), pp. e0149225. Date of Electronic Publication: 2025 Jul 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40693792 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: ADAR1 haploinsufficiency and sustained picornaviral RdRp dsRNA synthesis synergize to dysregulate RNA editing and cause multi-system interferonopathy. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Miller+CM%22">Miller CM</searchLink>; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Morrison+JH%22">Morrison JH</searchLink>; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Bankers+L%22">Bankers L</searchLink>; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Dran+R%22">Dran R</searchLink>; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Kendrick+JM%22">Kendrick JM</searchLink>; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Briggs+E%22">Briggs E</searchLink>; Department of Mechanical Engineering and BioFrontiers Institute, University of Colorado at Boulder, Boulder, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Ferguson+VL%22">Ferguson VL</searchLink>; Department of Mechanical Engineering and BioFrontiers Institute, University of Colorado at Boulder, Boulder, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Poeschla+EM%22">Poeschla EM</searchLink>; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101519231%22">MBio</searchLink> [mBio] 2025 Aug 13; Vol. 16 (8), pp. e0149225. <i>Date of Electronic Publication: </i>2025 Jul 22. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Microbiology%22">American Society for Microbiology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101519231 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2150-7511 (Electronic) <i>NLM ISO Abbreviation: </i>mBio <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40693792 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1128/mbio.01492-25 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e0149225 Titles: – TitleFull: ADAR1 haploinsufficiency and sustained picornaviral RdRp dsRNA synthesis synergize to dysregulate RNA editing and cause multi-system interferonopathy. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Miller CM – PersonEntity: Name: NameFull: Morrison JH – PersonEntity: Name: NameFull: Bankers L – PersonEntity: Name: NameFull: Dran R – PersonEntity: Name: NameFull: Kendrick JM – PersonEntity: Name: NameFull: Briggs E – PersonEntity: Name: NameFull: Ferguson VL – PersonEntity: Name: NameFull: Poeschla EM IsPartOfRelationships: – BibEntity: Dates: – D: 13 M: 08 Text: 2025 Aug 13 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2150-7511 Numbering: – Type: volume Value: 16 – Type: issue Value: 8 Titles: – TitleFull: MBio Type: main |
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