ADAR1 haploinsufficiency and sustained picornaviral RdRp dsRNA synthesis synergize to dysregulate RNA editing and cause multi-system interferonopathy.
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| Title: | ADAR1 haploinsufficiency and sustained picornaviral RdRp dsRNA synthesis synergize to dysregulate RNA editing and cause multi-system interferonopathy. |
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| Authors: | Miller CM; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA., Morrison JH; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA., Bankers L; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA., Dran R; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA., Kendrick JM; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA., Briggs E; Department of Mechanical Engineering and BioFrontiers Institute, University of Colorado at Boulder, Boulder, Colorado, USA., Ferguson VL; Department of Mechanical Engineering and BioFrontiers Institute, University of Colorado at Boulder, Boulder, Colorado, USA., Poeschla EM; Division of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora, Colorado, USA. |
| Source: | MBio [mBio] 2025 Aug 13; Vol. 16 (8), pp. e0149225. Date of Electronic Publication: 2025 Jul 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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