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Insulin Nanoemulsion Eye Drops for the Treatment of Dry Eye Disease in Sjögren's Disease: A Randomized Clinical Trial Phase I/II.

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Title: Insulin Nanoemulsion Eye Drops for the Treatment of Dry Eye Disease in Sjögren's Disease: A Randomized Clinical Trial Phase I/II.
Authors: Marzola MM; Core of Research in Ocular Physiopathology and Therapeutics (NAP-FTO), Ribeirao Preto 14049-900, Brazil.; Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil., Gutierrez DR; Core of Research in Ocular Physiopathology and Therapeutics (NAP-FTO), Ribeirao Preto 14049-900, Brazil.; Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil., Cintra BC; Core of Research in Ocular Physiopathology and Therapeutics (NAP-FTO), Ribeirao Preto 14049-900, Brazil.; Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil., Murashima AAB; Core of Research in Ocular Physiopathology and Therapeutics (NAP-FTO), Ribeirao Preto 14049-900, Brazil.; Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil., Dalmolin LF; School of Pharmaceutical Sciences of Ribeirao Preto, University of São Paulo, Ribeirao Preto 14040-903, Brazil., Garcia DM; Core of Research in Ocular Physiopathology and Therapeutics (NAP-FTO), Ribeirao Preto 14049-900, Brazil.; Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil., Lopez RFV; School of Pharmaceutical Sciences of Ribeirao Preto, University of São Paulo, Ribeirao Preto 14040-903, Brazil., Oliveira FR; Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil., Rocha EM; Core of Research in Ocular Physiopathology and Therapeutics (NAP-FTO), Ribeirao Preto 14049-900, Brazil.; Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil.
Source: Vision (Basel, Switzerland) [Vision (Basel)] 2025 Jul 09; Vol. 9 (3). Date of Electronic Publication: 2025 Jul 09.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101733282 Publication Model: Electronic Cited Medium: Internet ISSN: 2411-5150 (Electronic) Linking ISSN: 24115150 NLM ISO Abbreviation: Vision (Basel) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Insulin Nanoemulsion Eye Drops for the Treatment of Dry Eye Disease in Sjögren's Disease: A Randomized Clinical Trial Phase I/II.
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  Data: <searchLink fieldCode="AU" term="%22Marzola+MM%22">Marzola MM</searchLink>; Core of Research in Ocular Physiopathology and Therapeutics (NAP-FTO), Ribeirao Preto 14049-900, Brazil.; Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Gutierrez+DR%22">Gutierrez DR</searchLink>; Core of Research in Ocular Physiopathology and Therapeutics (NAP-FTO), Ribeirao Preto 14049-900, Brazil.; Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Cintra+BC%22">Cintra BC</searchLink>; Core of Research in Ocular Physiopathology and Therapeutics (NAP-FTO), Ribeirao Preto 14049-900, Brazil.; Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Murashima+AAB%22">Murashima AAB</searchLink>; Core of Research in Ocular Physiopathology and Therapeutics (NAP-FTO), Ribeirao Preto 14049-900, Brazil.; Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Dalmolin+LF%22">Dalmolin LF</searchLink>; School of Pharmaceutical Sciences of Ribeirao Preto, University of São Paulo, Ribeirao Preto 14040-903, Brazil.<br /><searchLink fieldCode="AU" term="%22Garcia+DM%22">Garcia DM</searchLink>; Core of Research in Ocular Physiopathology and Therapeutics (NAP-FTO), Ribeirao Preto 14049-900, Brazil.; Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Lopez+RFV%22">Lopez RFV</searchLink>; School of Pharmaceutical Sciences of Ribeirao Preto, University of São Paulo, Ribeirao Preto 14040-903, Brazil.<br /><searchLink fieldCode="AU" term="%22Oliveira+FR%22">Oliveira FR</searchLink>; Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Rocha+EM%22">Rocha EM</searchLink>; Core of Research in Ocular Physiopathology and Therapeutics (NAP-FTO), Ribeirao Preto 14049-900, Brazil.; Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Brazil.
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  Data: <searchLink fieldCode="JN" term="%22101733282%22">Vision (Basel, Switzerland)</searchLink> [Vision (Basel)] 2025 Jul 09; Vol. 9 (3). <i>Date of Electronic Publication: </i>2025 Jul 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI+AG%22">MDPI AG </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101733282 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2411-5150 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224115150%22">24115150 </searchLink><i>NLM ISO Abbreviation: </i>Vision (Basel) <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2025 Jul 09
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