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Boosting the ventrolateral periaqueductal gray-ventral tegmental area pathway by disinhibition of group II mGluRs alleviates chronic restraint stress-induced depression-like behavior in mice.

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Title: Boosting the ventrolateral periaqueductal gray-ventral tegmental area pathway by disinhibition of group II mGluRs alleviates chronic restraint stress-induced depression-like behavior in mice.
Authors: Lee MT; Faculty of Pharmaceutical Sciences, UCSI University, Cheras, Kuala Lumpur, Malaysia.; Center of Research for Mental Health and Wellbeing, UCSI University, Cheras, Kuala Lumpur, Malaysia.; School of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan., Peng WH; School of Medicine, National Tsing Hua University, Hsinchu, Taiwan., Hsu TW; School of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan.; Department of Psychiatry, E-DA Dachang Hospital, I-Shou University, Kaohsiung, Taiwan.; Department of Psychiatry, E-DA Hospital, I-Shou University, Kaohsiung, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Chu TH; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan., Teng YN; School of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan.; Department of Pharmacy, College of Pharmacy, China Medical University, Beitun District, Taichung City, Taiwan., Wu CC; School of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan., Lee YK; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan., Lan YY; School of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan., Ho YC; School of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan.
Source: Journal of psychopharmacology (Oxford, England) [J Psychopharmacol] 2025 Oct; Vol. 39 (10), pp. 1184-1200. Date of Electronic Publication: 2025 Jul 24.
Publication Type: Journal Article
Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 8907828 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1461-7285 (Electronic) Linking ISSN: 02698811 NLM ISO Abbreviation: J Psychopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Boosting the ventrolateral periaqueductal gray-ventral tegmental area pathway by disinhibition of group II mGluRs alleviates chronic restraint stress-induced depression-like behavior in mice.
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  Data: <searchLink fieldCode="AU" term="%22Lee+MT%22">Lee MT</searchLink>; Faculty of Pharmaceutical Sciences, UCSI University, Cheras, Kuala Lumpur, Malaysia.; Center of Research for Mental Health and Wellbeing, UCSI University, Cheras, Kuala Lumpur, Malaysia.; School of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Peng+WH%22">Peng WH</searchLink>; School of Medicine, National Tsing Hua University, Hsinchu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+TW%22">Hsu TW</searchLink>; School of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan.; Department of Psychiatry, E-DA Dachang Hospital, I-Shou University, Kaohsiung, Taiwan.; Department of Psychiatry, E-DA Hospital, I-Shou University, Kaohsiung, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chu+TH%22">Chu TH</searchLink>; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Teng+YN%22">Teng YN</searchLink>; School of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan.; Department of Pharmacy, College of Pharmacy, China Medical University, Beitun District, Taichung City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+CC%22">Wu CC</searchLink>; School of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+YK%22">Lee YK</searchLink>; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lan+YY%22">Lan YY</searchLink>; School of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ho+YC%22">Ho YC</searchLink>; School of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%228907828%22">Journal of psychopharmacology (Oxford, England)</searchLink> [J Psychopharmacol] 2025 Oct; Vol. 39 (10), pp. 1184-1200. <i>Date of Electronic Publication: </i>2025 Jul 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Sage+Publications%22">Sage Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8907828 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1461-7285 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202698811%22">02698811 </searchLink><i>NLM ISO Abbreviation: </i>J Psychopharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1177/02698811251351611
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              Text: 2025 Oct
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