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A multi-omic single-cell landscape reveals transcription and epigenetic regulatory features of t(8;21) AML.

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Title: A multi-omic single-cell landscape reveals transcription and epigenetic regulatory features of t(8;21) AML.
Authors: Li XP; Department of Hematologic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Gao Y; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Department of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Zhao BT; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Department of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Dai YT; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Mao JY; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Liang Y; Department of Hematologic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China. liangyang@sysucc.org.cn.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China. liangyang@sysucc.org.cn., Jiang L; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. jl11891@rjh.com.cn.
Source: Journal of translational medicine [J Transl Med] 2025 Jul 24; Vol. 23 (1), pp. 816. Date of Electronic Publication: 2025 Jul 24.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A multi-omic single-cell landscape reveals transcription and epigenetic regulatory features of t(8;21) AML.
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  Data: <searchLink fieldCode="AU" term="%22Li+XP%22">Li XP</searchLink>; Department of Hematologic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.<br /><searchLink fieldCode="AU" term="%22Gao+Y%22">Gao Y</searchLink>; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Department of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.<br /><searchLink fieldCode="AU" term="%22Zhao+BT%22">Zhao BT</searchLink>; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Department of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.<br /><searchLink fieldCode="AU" term="%22Dai+YT%22">Dai YT</searchLink>; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.<br /><searchLink fieldCode="AU" term="%22Mao+JY%22">Mao JY</searchLink>; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.<br /><searchLink fieldCode="AU" term="%22Liang+Y%22">Liang Y</searchLink>; Department of Hematologic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China. liangyang@sysucc.org.cn.; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China. liangyang@sysucc.org.cn.<br /><searchLink fieldCode="AU" term="%22Jiang+L%22">Jiang L</searchLink>; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. jl11891@rjh.com.cn.
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  Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2025 Jul 24; Vol. 23 (1), pp. 816. <i>Date of Electronic Publication: </i>2025 Jul 24.
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        Value: 10.1186/s12967-025-06659-0
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        Text: English
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              Text: 2025 Jul 24
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