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Impact of point-of-care maternal viral load testing at delivery on vertical HIV transmission risk assessment and neonatal prophylaxis: a cluster randomized trial.

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Title: Impact of point-of-care maternal viral load testing at delivery on vertical HIV transmission risk assessment and neonatal prophylaxis: a cluster randomized trial.
Authors: Lwilla AF; Mbeya Medical Research Center, National Institute for Medical Research, (NIMR), Mbeya, Tanzania., Elsbernd K; Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; Institute for Medical Information Processing, Biometry and Epidemiology (IBE), Faculty of Medicine, LMU Munich, Pettenkofer School of Public Health, Munich, Germany., Boniface S; Mbeya Medical Research Center, National Institute for Medical Research, (NIMR), Mbeya, Tanzania., Edom R; Mbeya Medical Research Center, National Institute for Medical Research, (NIMR), Mbeya, Tanzania., Mahumane A; Instituto Nacional de Saúde (INS), Maputo, Mozambique., Meggi B; Instituto Nacional de Saúde (INS), Maputo, Mozambique., Buck WC; David Geffen School of Medicine, University of California, Los Angeles, California, USA., Lequechane J; Instituto Nacional de Saúde (INS), Maputo, Mozambique., Pereira K; Instituto Nacional de Saúde (INS), Maputo, Mozambique., Chiwerengo N; Mbeya Medical Research Center, National Institute for Medical Research, (NIMR), Mbeya, Tanzania., Chale F; Instituto Nacional de Saúde (INS), Maputo, Mozambique., Mudenyanga C; Clinton Health Access Initiative (CHAI), Maputo, Mozambique., Mutsaka D; Clinton Health Access Initiative (CHAI), Maputo, Mozambique., Mueller M; Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany., Ntinginya NE; Mbeya Medical Research Center, National Institute for Medical Research, (NIMR), Mbeya, Tanzania., Taveira N; Instituto Universitário Egas Moniz (IUEM), Lisbon, Portugal., Hoelscher M; Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; German Center for Infection Research (DZIF), partner site Munich, Munich, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology, Infection and Pandemic Research, Munich, Germany.; Unit Global Health, Helmholtz Center Munich, German Research Center for Environmental Health (HMGU), Neuherberg, Germany., Jani I; Instituto Nacional de Saúde (INS), Maputo, Mozambique., Kroidl A; Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; German Center for Infection Research (DZIF), partner site Munich, Munich, Germany., Sabi I; Mbeya Medical Research Center, National Institute for Medical Research, (NIMR), Mbeya, Tanzania.
Corporate Authors: and the LIFE Study Consortium
Source: Journal of the International AIDS Society [J Int AIDS Soc] 2025 Aug; Vol. 28 (8), pp. e70021.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: Switzerland NLM ID: 101478566 Publication Model: Print Cited Medium: Internet ISSN: 1758-2652 (Electronic) Linking ISSN: 17582652 NLM ISO Abbreviation: J Int AIDS Soc Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Impact of point-of-care maternal viral load testing at delivery on vertical HIV transmission risk assessment and neonatal prophylaxis: a cluster randomized trial.
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  Data: <searchLink fieldCode="AU" term="%22Lwilla+AF%22">Lwilla AF</searchLink>; Mbeya Medical Research Center, National Institute for Medical Research, (NIMR), Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Elsbernd+K%22">Elsbernd K</searchLink>; Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; Institute for Medical Information Processing, Biometry and Epidemiology (IBE), Faculty of Medicine, LMU Munich, Pettenkofer School of Public Health, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Boniface+S%22">Boniface S</searchLink>; Mbeya Medical Research Center, National Institute for Medical Research, (NIMR), Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Edom+R%22">Edom R</searchLink>; Mbeya Medical Research Center, National Institute for Medical Research, (NIMR), Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Mahumane+A%22">Mahumane A</searchLink>; Instituto Nacional de Saúde (INS), Maputo, Mozambique.<br /><searchLink fieldCode="AU" term="%22Meggi+B%22">Meggi B</searchLink>; Instituto Nacional de Saúde (INS), Maputo, Mozambique.<br /><searchLink fieldCode="AU" term="%22Buck+WC%22">Buck WC</searchLink>; David Geffen School of Medicine, University of California, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Lequechane+J%22">Lequechane J</searchLink>; Instituto Nacional de Saúde (INS), Maputo, Mozambique.<br /><searchLink fieldCode="AU" term="%22Pereira+K%22">Pereira K</searchLink>; Instituto Nacional de Saúde (INS), Maputo, Mozambique.<br /><searchLink fieldCode="AU" term="%22Chiwerengo+N%22">Chiwerengo N</searchLink>; Mbeya Medical Research Center, National Institute for Medical Research, (NIMR), Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Chale+F%22">Chale F</searchLink>; Instituto Nacional de Saúde (INS), Maputo, Mozambique.<br /><searchLink fieldCode="AU" term="%22Mudenyanga+C%22">Mudenyanga C</searchLink>; Clinton Health Access Initiative (CHAI), Maputo, Mozambique.<br /><searchLink fieldCode="AU" term="%22Mutsaka+D%22">Mutsaka D</searchLink>; Clinton Health Access Initiative (CHAI), Maputo, Mozambique.<br /><searchLink fieldCode="AU" term="%22Mueller+M%22">Mueller M</searchLink>; Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ntinginya+NE%22">Ntinginya NE</searchLink>; Mbeya Medical Research Center, National Institute for Medical Research, (NIMR), Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Taveira+N%22">Taveira N</searchLink>; Instituto Universitário Egas Moniz (IUEM), Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Hoelscher+M%22">Hoelscher M</searchLink>; Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; German Center for Infection Research (DZIF), partner site Munich, Munich, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology, Infection and Pandemic Research, Munich, Germany.; Unit Global Health, Helmholtz Center Munich, German Research Center for Environmental Health (HMGU), Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Jani+I%22">Jani I</searchLink>; Instituto Nacional de Saúde (INS), Maputo, Mozambique.<br /><searchLink fieldCode="AU" term="%22Kroidl+A%22">Kroidl A</searchLink>; Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; German Center for Infection Research (DZIF), partner site Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Sabi+I%22">Sabi I</searchLink>; Mbeya Medical Research Center, National Institute for Medical Research, (NIMR), Mbeya, Tanzania.
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  Data: <searchLink fieldCode="CA" term="%22and+the+LIFE+Study+Consortium%22">and the LIFE Study Consortium</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101478566%22">Journal of the International AIDS Society</searchLink> [J Int AIDS Soc] 2025 Aug; Vol. 28 (8), pp. e70021.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Inc%22">John Wiley & Sons, Inc </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101478566 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1758-2652 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217582652%22">17582652 </searchLink><i>NLM ISO Abbreviation: </i>J Int AIDS Soc <i>Subsets: </i>MEDLINE
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        Value: 10.1002/jia2.70021
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              Text: 2025 Aug
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