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Thrombospondin-2 is a performant biomarker of at-risk MASH and advanced MASH fibrosis in a large multicentre European cohort.

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Title: Thrombospondin-2 is a performant biomarker of at-risk MASH and advanced MASH fibrosis in a large multicentre European cohort.
Authors: Ratziu V; Sorbonne Universite, Paris, France.; ICAN Institute for Cardiometabolism and Nutrition, Paris, France.; INSERM UMRS 1138 CRC, Paris, France., Surabattula R; Institute of Translational Immunology, Johannes Gutenberg University, Mainz, Germany., Bugianesi E; Medical Sciences, University of Turin, Torino, Italy., Schattenberg JM; Saarland University Medical Center Homburg, Germany, Germany., Myneni S; Medical Sciences, University of Turin, Torino, Italy., Rosso C; Medical Sciences, University of Turin, Torino, Italy., Armandi A; Department of Medical Sciences, Division of Gastroenterology and Hepatology, University of Turin, Torino, Italy., Pais R; Sorbonne Universite, Paris, France., Kara L; ICAN Institute for Cardiometabolism and Nutrition, Paris, France., Charlotte F; Department of Pathology, University Hospital Pitié Salpêtrière, Paris, France., Ponnaiah M; ICAN Institute for Cardiometabolism and Nutrition, Paris, France., Schuppan D; Institute of Translational Immunology, Johannes Gutenberg University, Mainz, Germany Detlef.Schuppan@unimedizin-mainz.de.; Research Center for Immune Therapy, Johannes Gutenberg-University, Mainz, Germany.; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Source: Gut [Gut] 2026 May 12; Vol. 75 (6), pp. 1226-1236. Date of Electronic Publication: 2026 May 12.
Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Thrombospondin-2 is a performant biomarker of at-risk MASH and advanced MASH fibrosis in a large multicentre European cohort.
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  Data: <searchLink fieldCode="AU" term="%22Ratziu+V%22">Ratziu V</searchLink>; Sorbonne Universite, Paris, France.; ICAN Institute for Cardiometabolism and Nutrition, Paris, France.; INSERM UMRS 1138 CRC, Paris, France.<br /><searchLink fieldCode="AU" term="%22Surabattula+R%22">Surabattula R</searchLink>; Institute of Translational Immunology, Johannes Gutenberg University, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Bugianesi+E%22">Bugianesi E</searchLink>; Medical Sciences, University of Turin, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Schattenberg+JM%22">Schattenberg JM</searchLink>; Saarland University Medical Center Homburg, Germany, Germany.<br /><searchLink fieldCode="AU" term="%22Myneni+S%22">Myneni S</searchLink>; Medical Sciences, University of Turin, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Rosso+C%22">Rosso C</searchLink>; Medical Sciences, University of Turin, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Armandi+A%22">Armandi A</searchLink>; Department of Medical Sciences, Division of Gastroenterology and Hepatology, University of Turin, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Pais+R%22">Pais R</searchLink>; Sorbonne Universite, Paris, France.<br /><searchLink fieldCode="AU" term="%22Kara+L%22">Kara L</searchLink>; ICAN Institute for Cardiometabolism and Nutrition, Paris, France.<br /><searchLink fieldCode="AU" term="%22Charlotte+F%22">Charlotte F</searchLink>; Department of Pathology, University Hospital Pitié Salpêtrière, Paris, France.<br /><searchLink fieldCode="AU" term="%22Ponnaiah+M%22">Ponnaiah M</searchLink>; ICAN Institute for Cardiometabolism and Nutrition, Paris, France.<br /><searchLink fieldCode="AU" term="%22Schuppan+D%22">Schuppan D</searchLink>; Institute of Translational Immunology, Johannes Gutenberg University, Mainz, Germany Detlef.Schuppan@unimedizin-mainz.de.; Research Center for Immune Therapy, Johannes Gutenberg-University, Mainz, Germany.; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
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  Data: <searchLink fieldCode="JN" term="%222985108R%22">Gut</searchLink> [Gut] 2026 May 12; Vol. 75 (6), pp. 1226-1236. <i>Date of Electronic Publication: </i>2026 May 12.
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  Data: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22British+Medical+Assn%22">British Medical Assn </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>2985108R <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1468-3288 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200175749%22">00175749 </searchLink><i>NLM ISO Abbreviation: </i>Gut <i>Subsets: </i>MEDLINE
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        Value: 10.1136/gutjnl-2025-335598
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              Text: 2026 May 12
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