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A GWAS Meta-meta-analysis and In-depth Silico Pharmacogenomic Investigations in Identification of APOE and Other Genes Associated with Pain, Anti-inflammatory, and Immunomodulating Agents in Opioid Use Disorder (OUD) Derived from 14.91 M Subjects.

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Title: A GWAS Meta-meta-analysis and In-depth Silico Pharmacogenomic Investigations in Identification of APOE and Other Genes Associated with Pain, Anti-inflammatory, and Immunomodulating Agents in Opioid Use Disorder (OUD) Derived from 14.91 M Subjects.
Authors: Sharafshah A; Division of Genetics, Department of Cell and Molecular Biology and Microbiology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, Iran.; Cellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran., Motovali-Bashi M; Division of Genetics, Department of Cell and Molecular Biology and Microbiology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, Iran. mbashi@sci.ui.ac.ir., Blum K; Division of Addiction Research & Education, Center for Sports, Exercise & Mental Health, Western University, Health Sciences, Pomona, CA, USA. drd2gene@gmail.com., Lewandrowski KU; Division of Personalized Pain Medicine & Education, Center for Advanced Spine Care of Southern Arizona, Tucson, AZ, USA.; Department of Orthopaedics, Fundación Universitaria Sanitas, Bogotá, DC, Colombia.; Department of Orthopaedics, Hospital Universitário Gaffre e Guinle, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, Brazil., Gold MS; Department of Psychiatry, Washington University, St. Louis, MO, USA. mgold9876@wustl.edu., Keshavarz P; Cellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran., Thanos PK; Behavioral Neuropharmacology and Neuroimaging Laboratory on Addictions, Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biosciences, Clinical Research Institute on Addictions, State University of New York at Buffalo, Buffalo, NY, USA. thanos@buffalo.edu.
Source: Cellular and molecular neurobiology [Cell Mol Neurobiol] 2025 Jul 31; Vol. 45 (1), pp. 76. Date of Electronic Publication: 2025 Jul 31.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 8200709 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6830 (Electronic) Linking ISSN: 02724340 NLM ISO Abbreviation: Cell Mol Neurobiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A GWAS Meta-meta-analysis and In-depth Silico Pharmacogenomic Investigations in Identification of APOE and Other Genes Associated with Pain, Anti-inflammatory, and Immunomodulating Agents in Opioid Use Disorder (OUD) Derived from 14.91 M Subjects.
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  Data: <searchLink fieldCode="AU" term="%22Sharafshah+A%22">Sharafshah A</searchLink>; Division of Genetics, Department of Cell and Molecular Biology and Microbiology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, Iran.; Cellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.<br /><searchLink fieldCode="AU" term="%22Motovali-Bashi+M%22">Motovali-Bashi M</searchLink>; Division of Genetics, Department of Cell and Molecular Biology and Microbiology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, Iran. mbashi@sci.ui.ac.ir.<br /><searchLink fieldCode="AU" term="%22Blum+K%22">Blum K</searchLink>; Division of Addiction Research & Education, Center for Sports, Exercise & Mental Health, Western University, Health Sciences, Pomona, CA, USA. drd2gene@gmail.com.<br /><searchLink fieldCode="AU" term="%22Lewandrowski+KU%22">Lewandrowski KU</searchLink>; Division of Personalized Pain Medicine & Education, Center for Advanced Spine Care of Southern Arizona, Tucson, AZ, USA.; Department of Orthopaedics, Fundación Universitaria Sanitas, Bogotá, DC, Colombia.; Department of Orthopaedics, Hospital Universitário Gaffre e Guinle, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Gold+MS%22">Gold MS</searchLink>; Department of Psychiatry, Washington University, St. Louis, MO, USA. mgold9876@wustl.edu.<br /><searchLink fieldCode="AU" term="%22Keshavarz+P%22">Keshavarz P</searchLink>; Cellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.<br /><searchLink fieldCode="AU" term="%22Thanos+PK%22">Thanos PK</searchLink>; Behavioral Neuropharmacology and Neuroimaging Laboratory on Addictions, Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biosciences, Clinical Research Institute on Addictions, State University of New York at Buffalo, Buffalo, NY, USA. thanos@buffalo.edu.
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  Data: <searchLink fieldCode="JN" term="%228200709%22">Cellular and molecular neurobiology</searchLink> [Cell Mol Neurobiol] 2025 Jul 31; Vol. 45 (1), pp. 76. <i>Date of Electronic Publication: </i>2025 Jul 31.
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