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Pipeline to evaluate YAP-TEAD inhibitors indicates TEAD inhibition represses NF2-mutant mesothelioma.

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Title: Pipeline to evaluate YAP-TEAD inhibitors indicates TEAD inhibition represses NF2-mutant mesothelioma.
Authors: Cunningham R; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK., Jia S; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK., Purohit K; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK., Fairley MN; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK., Maniak MK; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK., Lin Y; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK., Hui NS; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK., Graham RE; Centre for Clinical Brain Sciences, Anne Rowling Regenerative Neurology Clinic, The University of Edinburgh, Edinburgh, UK., Rossi AG; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK., Cholewa-Waclaw J; High Content Screening Facility, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, UK., Bagnaninchi PO; Centre for Regenerative Medicine, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, UK., Carragher NO; Cancer Research UK Scotland Centre, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK., Hansen CG; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK Carsten.G.Hansen@ed.ac.uk.
Source: Life science alliance [Life Sci Alliance] 2025 Jul 31; Vol. 8 (10). Date of Electronic Publication: 2025 Jul 31 (Print Publication: 2025).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Life Science Alliance, LLC Country of Publication: United States NLM ID: 101728869 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2575-1077 (Electronic) Linking ISSN: 25751077 NLM ISO Abbreviation: Life Sci Alliance Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pipeline to evaluate YAP-TEAD inhibitors indicates TEAD inhibition represses NF2-mutant mesothelioma.
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  Data: <searchLink fieldCode="AU" term="%22Cunningham+R%22">Cunningham R</searchLink>; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Jia+S%22">Jia S</searchLink>; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Purohit+K%22">Purohit K</searchLink>; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Fairley+MN%22">Fairley MN</searchLink>; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Maniak+MK%22">Maniak MK</searchLink>; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Lin+Y%22">Lin Y</searchLink>; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Hui+NS%22">Hui NS</searchLink>; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Graham+RE%22">Graham RE</searchLink>; Centre for Clinical Brain Sciences, Anne Rowling Regenerative Neurology Clinic, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Rossi+AG%22">Rossi AG</searchLink>; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Cholewa-Waclaw+J%22">Cholewa-Waclaw J</searchLink>; High Content Screening Facility, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Bagnaninchi+PO%22">Bagnaninchi PO</searchLink>; Centre for Regenerative Medicine, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Carragher+NO%22">Carragher NO</searchLink>; Cancer Research UK Scotland Centre, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Hansen+CG%22">Hansen CG</searchLink>; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, BioQuarter, Edinburgh, UK Carsten.G.Hansen@ed.ac.uk.
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