High-Grade Early-Onset Prostate Cancer: Assessment of TMPRSS2::ERG -Negative Tumors Suggests Low Frequency of Germline Alterations and a Pathogenic Role for HOXB13.

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Title: High-Grade Early-Onset Prostate Cancer: Assessment of TMPRSS2::ERG -Negative Tumors Suggests Low Frequency of Germline Alterations and a Pathogenic Role for HOXB13.
Authors: Maharjan D; Department of Pathology, Indiana University School of Medicine, Indianapolis, IN., Siegmund S; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Michalova K; Department of Pathology and Laboratory Medicine, Biopticka laborator s.r.o., Pilsen, Czech Republic., Odintsov I; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Hornick JL; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Nair V; Department of Pathology, Indiana University School of Medicine, Indianapolis, IN., Idrees MT; Department of Pathology, Indiana University School of Medicine, Indianapolis, IN., Collins K; Department of Pathology, Indiana University School of Medicine, Indianapolis, IN., Gordetsky JB; Department of Pathology and Department of Urology, Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN., Osunkoya AO; Departments of Pathology and Urology, Emory University School of Medicine, Atlanta, GA., Cheng L; Department of Pathology and Laboratory Medicine, Alpert Medical School of Brown University, Providence, RI., Miyamoto H; Departments of Pathology and Laboratory Medicine and Urology, University of Rochester Medical Center, Rochester, NY., Sangoi AR; Department of Pathology and Laboratory Medicine, Stanford University School of Medicine, Stanford, CA., Wu DJ; Department of Pathology and Laboratory Medicine, Stanford University School of Medicine, Stanford, CA., Ricci C; Pathology Unit, DIAP-Dipartimento Interaziendale di anatomia patologica di Bologna, Maggiore Hospital-AUSL Bologna., Mollica V; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna., Raspollini MR; Department of Pathology, University Hospital Careggi, Florence, Italy., Contreras F; Department of Pathology, Clínica Universitaria Unión Médica, Pontificia Universidad Católica Madre y Maestra, Santiago, Dominican Republic., Bernal MPP; Department of Pathology, Clínica Universitaria Unión Médica, Pontificia Universidad Católica Madre y Maestra, Santiago, Dominican Republic., Fernandez IM; Department of Pathology, Clínica Universitaria Unión Médica, Pontificia Universidad Católica Madre y Maestra, Santiago, Dominican Republic., Rodriguez A; Department of Pathology, Pathox Diagnóstico Histopatológico, Ciudad de México, Mexico., Lobo A; Department of Pathology and Laboratory Medicine, Kapoor Centre of Urology and Pathology, Raipur., Mohanty SK; Department of Pathology and Laboratory Medicine, Advanced Medical Research Institute and CORE Diagnostics, Gurgaon, India., Sharma S; Department of Pathology and Laboratory Medicine, Advanced Medical Research Institute and CORE Diagnostics, Gurgaon, India., Goksel M; Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL., Acosta AM; Department of Pathology, Indiana University School of Medicine, Indianapolis, IN.
Source: The American journal of surgical pathology [Am J Surg Pathol] 2025 Dec 01; Vol. 49 (12), pp. 1279-1287. Date of Electronic Publication: 2025 Aug 01.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 7707904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-0979 (Electronic) Linking ISSN: 01475185 NLM ISO Abbreviation: Am J Surg Pathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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