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Isolation of genetically diverse influenza antibodies highlights the role of IG germline gene variation and informs the design of population-comprehensive vaccine strategies.

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Title: Isolation of genetically diverse influenza antibodies highlights the role of IG germline gene variation and informs the design of population-comprehensive vaccine strategies.
Authors: Fischer AA; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden., Corcoran M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden., Brouwer PJM; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA., Chernyshev M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden., Gillespie RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Nicoletto A; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden., Loeffler JR; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA., Ferguson JA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA., Rodriguez AJ; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA., Narang S; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden., van Gils MJ; Amsterdam UMC, University of Amsterdam, Department of Medical Microbiology and Infection Prevention, Amsterdam, Netherlands., Castro Dopico X; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden., Kanekiyo M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA., Han J; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA., Karlsson Hedestam GB; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jul 07. Date of Electronic Publication: 2025 Jul 07.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Isolation of genetically diverse influenza antibodies highlights the role of IG germline gene variation and informs the design of population-comprehensive vaccine strategies.
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  Data: <searchLink fieldCode="AU" term="%22Fischer+AA%22">Fischer AA</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Corcoran+M%22">Corcoran M</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Brouwer+PJM%22">Brouwer PJM</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chernyshev+M%22">Chernyshev M</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Gillespie+RA%22">Gillespie RA</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Nicoletto+A%22">Nicoletto A</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Loeffler+JR%22">Loeffler JR</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ferguson+JA%22">Ferguson JA</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rodriguez+AJ%22">Rodriguez AJ</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Narang+S%22">Narang S</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22van+Gils+MJ%22">van Gils MJ</searchLink>; Amsterdam UMC, University of Amsterdam, Department of Medical Microbiology and Infection Prevention, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Castro+Dopico+X%22">Castro Dopico X</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Kanekiyo+M%22">Kanekiyo M</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ward+AB%22">Ward AB</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Han+J%22">Han J</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Karlsson+Hedestam+GB%22">Karlsson Hedestam GB</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden.
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