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HLA-A∗03:01 as predictive genetic biomarker for glatiramer acetate treatment response in multiple sclerosis: a retrospective cohort analysis.

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Title: HLA-A∗03:01 as predictive genetic biomarker for glatiramer acetate treatment response in multiple sclerosis: a retrospective cohort analysis.
Authors: Zhang BC; Adaptive Biotechnologies, Seattle, WA, USA., Schneider-Hohendorf T; Department of Neurology, University of Muenster, Muenster, Germany., Elyanow R; Adaptive Biotechnologies, Seattle, WA, USA., Pignolet B; Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), University of Toulouse, CNRS, INSERM, UPS, Toulouse, France., Falk S; Department of Neurology, University of Muenster, Muenster, Germany., Wünsch C; Department of Neurology, University of Muenster, Muenster, Germany., Deffner M; Department of Neurology, University of Muenster, Muenster, Germany., Yusko E; Adaptive Biotechnologies, Seattle, WA, USA., May D; Adaptive Biotechnologies, Seattle, WA, USA., Mattox D; Adaptive Biotechnologies, Seattle, WA, USA., Dawin E; Department of Neurology, University of Muenster, Muenster, Germany., Gerdes LA; Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University Munich, Munich, Germany; Biomedical Center, Faculty of Medicine, Ludwig Maximilian University Munich, Martinsried, Germany; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany., Bucciarelli F; Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), University of Toulouse, CNRS, INSERM, UPS, Toulouse, France., Revie L; Department of Neurology, University of Muenster, Muenster, Germany., Antony G; Central Information Office German Competence Network of Multiple Sclerosis, Philipps University Marburg, Marburg, Germany., Jarius S; Department of Neurology, University of Heidelberg, Heidelberg, Germany., Seidel C; Department of Neurology, University of Leipzig, Leipzig, Germany., Senel M; Department of Neurology, University of Ulm, Ulm, Germany., Bittner S; Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine-Main Neuroscience Network (rmn), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Luessi F; Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine-Main Neuroscience Network (rmn), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Havla J; Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University Munich, Munich, Germany., Knop M; Max Planck Institute of Psychiatry, Munich, Germany., Friese MA; Institute of Neuroimmunology and Multiple Sclerosis, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Neurology, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Rothacher S; Department of Neurology and Clinical Neurophysiology, Medical Faculty, University of Augsburg, Augsburg, Germany., Salmen A; Department of Neurology, St. Josef-hospital, Ruhr-University Bochum, Bochum, Germany., Hayashi F; Well Institute for Neurosciences, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Henry R; Well Institute for Neurosciences, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Caillier S; Well Institute for Neurosciences, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Santaniello A; Well Institute for Neurosciences, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Seipelt M; Department of Neurology, University Hospital Marburg, Philipps-University Marburg, Marburg, Germany., Heesen C; Institute of Neuroimmunology and Multiple Sclerosis, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Neurology, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Nischwitz S; Max Planck Institute of Psychiatry, Munich, Germany., Bayas A; Department of Neurology and Clinical Neurophysiology, Medical Faculty, University of Augsburg, Augsburg, Germany., Tumani H; Department of Neurology, University of Ulm, Ulm, Germany., Then Bergh F; Department of Neurology, University of Leipzig, Leipzig, Germany., Meyer Zu Hörste G; Department of Neurology, University of Muenster, Muenster, Germany., Kümpfel T; Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University Munich, Munich, Germany., Gross CC; Department of Neurology, University of Muenster, Muenster, Germany., Wildemann B; Department of Neurology, University of Heidelberg, Heidelberg, Germany., Kerschensteiner M; Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University Munich, Munich, Germany; Biomedical Center, Faculty of Medicine, Ludwig Maximilian University Munich, Martinsried, Germany; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany., Gold R; Department of Neurology, St. Josef-hospital, Ruhr-University Bochum, Bochum, Germany., Meuth SG; Department of Neurology, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany., Zipp F; Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine-Main Neuroscience Network (rmn), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Cree BAC; Well Institute for Neurosciences, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Oksenberg J; Well Institute for Neurosciences, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Wilson MR; Well Institute for Neurosciences, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Hauser SL; Well Institute for Neurosciences, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Zamvil SS; Well Institute for Neurosciences, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Klotz L; Department of Neurology, University of Muenster, Muenster, Germany., Liblau R; Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), University of Toulouse, CNRS, INSERM, UPS, Toulouse, France., Robins H; Adaptive Biotechnologies, Seattle, WA, USA., Sabatino JJ Jr; Well Institute for Neurosciences, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Wiendl H; Department of Neurology, University of Muenster, Muenster, Germany; Department of Neurology and Neurophysiology, University of Freiburg, Freiburg, Germany., Schwab N; Department of Neurology, University of Muenster, Muenster, Germany. Electronic address: Nicholas.Schwab@ukmuenster.de.
Corporate Authors: University of California San Francisco MS-EPIC Team; Well Institute for Neurosciences, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., German Competence Network Multiple Sclerosis (KKNMS)
Source: EBioMedicine [EBioMedicine] 2025 Aug; Vol. 118, pp. 105873. Date of Electronic Publication: 2025 Jul 31.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
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  Data: HLA-A∗03:01 as predictive genetic biomarker for glatiramer acetate treatment response in multiple sclerosis: a retrospective cohort analysis.
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      – PersonEntity:
          Name:
            NameFull: Wiendl H
      – PersonEntity:
          Name:
            NameFull: Schwab N
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 08
              Text: 2025 Aug
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2352-3964
          Numbering:
            – Type: volume
              Value: 118
          Titles:
            – TitleFull: EBioMedicine
              Type: main
ResultId 1