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Impact of modified dexamethasone administration sequence on infusion reaction incidence in HER2-positive breast cancer: a randomized multicenter trial.

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Title: Impact of modified dexamethasone administration sequence on infusion reaction incidence in HER2-positive breast cancer: a randomized multicenter trial.
Authors: Matsunuma R; Department of Breast Surgery, Shizuoka Prefectural Hospital Organization, Shizuoka General Hospital, 4-27-1 Kita-Ando Aoi-ku, Shizuoka, 420-8527, Japan. r-matsunuma@nifty.com., Nakagaki S; Department of Pharmacy, Shizuoka Prefectural Hospital Organization, Shizuoka General Hospital, Shizuoka, 420-8527, Japan., Nakatani E; Department of Biostatistics and Health Data Science, Graduate School of Medical Science, Nagoya City University, Aichi, 466-8550, Japan., Kikuchi M; Department of Surgery, Japanese Red Cross Shizuoka Hospital, Shizuoka, 420-0853, Japan., Wada N; Department of Clinical Oncology, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Chiba, 272-8513, Japan., Yonezawa K; Department of Surgery, Shizuoka City Hospital, Shizuoka, 420-8527, Japan., Isono T; Department of Surgery, Shimada General Medical Center, Shizuoka, 427-8502, Japan., Hayami R; Department of Breast Surgery, Shizuoka Prefectural Hospital Organization, Shizuoka General Hospital, 4-27-1 Kita-Ando Aoi-ku, Shizuoka, 420-8527, Japan., Kaga M; Department of Pharmacy, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Chiba, 272-8513, Japan., Tsuneizumi M; Department of Breast Surgery, Shizuoka Prefectural Hospital Organization, Shizuoka General Hospital, 4-27-1 Kita-Ando Aoi-ku, Shizuoka, 420-8527, Japan.
Source: Breast cancer (Tokyo, Japan) [Breast Cancer] 2025 Nov; Vol. 32 (6), pp. 1308-1317. Date of Electronic Publication: 2025 Aug 02.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Maruzen Co Country of Publication: Japan NLM ID: 100888201 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-4233 (Electronic) Linking ISSN: 13406868 NLM ISO Abbreviation: Breast Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Impact of modified dexamethasone administration sequence on infusion reaction incidence in HER2-positive breast cancer: a randomized multicenter trial.
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  Data: <searchLink fieldCode="AU" term="%22Matsunuma+R%22">Matsunuma R</searchLink>; Department of Breast Surgery, Shizuoka Prefectural Hospital Organization, Shizuoka General Hospital, 4-27-1 Kita-Ando Aoi-ku, Shizuoka, 420-8527, Japan. r-matsunuma@nifty.com.<br /><searchLink fieldCode="AU" term="%22Nakagaki+S%22">Nakagaki S</searchLink>; Department of Pharmacy, Shizuoka Prefectural Hospital Organization, Shizuoka General Hospital, Shizuoka, 420-8527, Japan.<br /><searchLink fieldCode="AU" term="%22Nakatani+E%22">Nakatani E</searchLink>; Department of Biostatistics and Health Data Science, Graduate School of Medical Science, Nagoya City University, Aichi, 466-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Kikuchi+M%22">Kikuchi M</searchLink>; Department of Surgery, Japanese Red Cross Shizuoka Hospital, Shizuoka, 420-0853, Japan.<br /><searchLink fieldCode="AU" term="%22Wada+N%22">Wada N</searchLink>; Department of Clinical Oncology, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Chiba, 272-8513, Japan.<br /><searchLink fieldCode="AU" term="%22Yonezawa+K%22">Yonezawa K</searchLink>; Department of Surgery, Shizuoka City Hospital, Shizuoka, 420-8527, Japan.<br /><searchLink fieldCode="AU" term="%22Isono+T%22">Isono T</searchLink>; Department of Surgery, Shimada General Medical Center, Shizuoka, 427-8502, Japan.<br /><searchLink fieldCode="AU" term="%22Hayami+R%22">Hayami R</searchLink>; Department of Breast Surgery, Shizuoka Prefectural Hospital Organization, Shizuoka General Hospital, 4-27-1 Kita-Ando Aoi-ku, Shizuoka, 420-8527, Japan.<br /><searchLink fieldCode="AU" term="%22Kaga+M%22">Kaga M</searchLink>; Department of Pharmacy, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Chiba, 272-8513, Japan.<br /><searchLink fieldCode="AU" term="%22Tsuneizumi+M%22">Tsuneizumi M</searchLink>; Department of Breast Surgery, Shizuoka Prefectural Hospital Organization, Shizuoka General Hospital, 4-27-1 Kita-Ando Aoi-ku, Shizuoka, 420-8527, Japan.
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  Data: <searchLink fieldCode="JN" term="%22100888201%22">Breast cancer (Tokyo, Japan)</searchLink> [Breast Cancer] 2025 Nov; Vol. 32 (6), pp. 1308-1317. <i>Date of Electronic Publication: </i>2025 Aug 02.
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  Data: Journal Article; Randomized Controlled Trial; Multicenter Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Maruzen+Co%22">Maruzen Co </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>100888201 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1880-4233 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213406868%22">13406868 </searchLink><i>NLM ISO Abbreviation: </i>Breast Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s12282-025-01752-0
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      – Code: eng
        Text: English
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              Text: 2025 Nov
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              Y: 2025
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