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Real-world patterns of immunoglobulin replacement therapy for infection prevention in common variable immunodeficiency: a multicenter nationwide study.

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Title: Real-world patterns of immunoglobulin replacement therapy for infection prevention in common variable immunodeficiency: a multicenter nationwide study.
Authors: Moral Moral P; Primary Immunodeficiencies Unit, Department of Internal Medicine, University and Polytechnic Hospital La Fe, Valencia, Spain.; Research Group of Chronic Diseases and HIV Infection, Health Research Institute La Fe, Valencia, Spain., Garcia-Bustos V; Primary Immunodeficiencies Unit, Department of Internal Medicine, University and Polytechnic Hospital La Fe, Valencia, Spain.; Severe Infection Research Group, Health Research Institute La Fe, Valencia, Spain., Balastegui-Martin H; Primary Immunodeficiencies Unit, Department of Internal Medicine, University and Polytechnic Hospital La Fe, Valencia, Spain.; Research Group of Chronic Diseases and HIV Infection, Health Research Institute La Fe, Valencia, Spain., Martínez Mercader S; Primary Immunodeficiencies Unit, Department of Internal Medicine, University and Polytechnic Hospital La Fe, Valencia, Spain.; Research Group of Chronic Diseases and HIV Infection, Health Research Institute La Fe, Valencia, Spain., Bracke C; Infectious Diseases Service, Germans Trias i Pujol Hospital, Badalona, Spain.; Fight Infections Foundation, Germans Trias i Pujol Hospital, Badalona, Spain., Mateu L; Infectious Diseases Service, Germans Trias i Pujol Hospital, Badalona, Spain.; Fight Infections Foundation, Germans Trias i Pujol Hospital, Badalona, Spain., Solanich X; Adult Primary Immunodefciency Unit (UFIPA), Internal Medicine Department, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain.; The Systemic, Vascular Diseases and Ageing Group, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Clinical Sciences Department, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain., Antolí A; Adult Primary Immunodefciency Unit (UFIPA), Internal Medicine Department, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain.; The Systemic, Vascular Diseases and Ageing Group, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Clinical Sciences Department, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain., Carrillo-Linares JL; Department of Internal Medicine, Virgen de la Victoria University Hospital, Málaga, Spain., Robles-Marhuenda Á; Department of Internal Medicine, La Paz University Hospital, Madrid, Spain., Puchades F; Department of Internal Medicine, University General Hospital of Valencia, Valencia, Spain., Pelaez Ballesta A; Department of Internal Medicine, Rafael Méndez University Hospital, Murcia, Spain., López-Osle N; Department of Internal Medicine, Cruces University Hospital, Bizkaia, Spain., Torralba-Cabeza MÁ; Unit for Rare Diseases, Internal Medicine Service, Lozano Blesa University Hospital, Zaragoza, Spain., Bielsa Masdeu AM; Department of Internal Medicine, Miguel Servet University Hospital, Zaragoza, Spain., Gil Niño J; Immunodeficiencies Clinic, Internal Medicine Department, 12 de Octubre Hospital, Madrid, Spain., Tornador Gaya N; Department of Internal Medicine, University General Hospital of Castellón, Castellón, Spain., Pascual Castellanos G; Department of Internal Medicine, University General Hospital of Castellón, Castellón, Spain., Sánchez-Martínez R; Internal Medicine Department, Dr. Balmis General University Hospital, Alicante Institute for Health and Biomedical Research, Alicante, Spain., Barragán-Casas JM; Department of Internal Medicine, Complejo Asistencial de Ávila, Ávila, Spain., González-García A; Systemic Autoimmune Diseases Unit, Internal Medicine Service, Ramón y Cajal Hospital, Ramón y Cajal Health Research Institute, Madrid, Spain., Patier de la Peña JL; Department of Internal Medicine, University Hospital Alcorcón Foundation, Madrid, Spain., López-Wolf D; Department of Internal Medicine, General University Hospital of Elche, Alicante, Spain., Mora Rufete A; Department of Internal Medicine, General University Hospital of Elche, Alicante, Spain., Canovas Mora A; Department of Internal Medicine, General University Hospital of Elche, Alicante, Spain., Cabañero-Navalon MD; Primary Immunodeficiencies Unit, Department of Internal Medicine, University and Polytechnic Hospital La Fe, Valencia, Spain.; Research Group of Chronic Diseases and HIV Infection, Health Research Institute La Fe, Valencia, Spain.
Source: Frontiers in immunology [Front Immunol] 2025 Jul 23; Vol. 16, pp. 1640290. Date of Electronic Publication: 2025 Jul 23 (Print Publication: 2025).
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Real-world patterns of immunoglobulin replacement therapy for infection prevention in common variable immunodeficiency: a multicenter nationwide study.
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  Data: <searchLink fieldCode="AU" term="%22Moral+Moral+P%22">Moral Moral P</searchLink>; Primary Immunodeficiencies Unit, Department of Internal Medicine, University and Polytechnic Hospital La Fe, Valencia, Spain.; Research Group of Chronic Diseases and HIV Infection, Health Research Institute La Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Garcia-Bustos+V%22">Garcia-Bustos V</searchLink>; Primary Immunodeficiencies Unit, Department of Internal Medicine, University and Polytechnic Hospital La Fe, Valencia, Spain.; Severe Infection Research Group, Health Research Institute La Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Balastegui-Martin+H%22">Balastegui-Martin H</searchLink>; Primary Immunodeficiencies Unit, Department of Internal Medicine, University and Polytechnic Hospital La Fe, Valencia, Spain.; Research Group of Chronic Diseases and HIV Infection, Health Research Institute La Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Martínez+Mercader+S%22">Martínez Mercader S</searchLink>; Primary Immunodeficiencies Unit, Department of Internal Medicine, University and Polytechnic Hospital La Fe, Valencia, Spain.; Research Group of Chronic Diseases and HIV Infection, Health Research Institute La Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Bracke+C%22">Bracke C</searchLink>; Infectious Diseases Service, Germans Trias i Pujol Hospital, Badalona, Spain.; Fight Infections Foundation, Germans Trias i Pujol Hospital, Badalona, Spain.<br /><searchLink fieldCode="AU" term="%22Mateu+L%22">Mateu L</searchLink>; Infectious Diseases Service, Germans Trias i Pujol Hospital, Badalona, Spain.; Fight Infections Foundation, Germans Trias i Pujol Hospital, Badalona, Spain.<br /><searchLink fieldCode="AU" term="%22Solanich+X%22">Solanich X</searchLink>; Adult Primary Immunodefciency Unit (UFIPA), Internal Medicine Department, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain.; The Systemic, Vascular Diseases and Ageing Group, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Clinical Sciences Department, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Antolí+A%22">Antolí A</searchLink>; Adult Primary Immunodefciency Unit (UFIPA), Internal Medicine Department, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain.; The Systemic, Vascular Diseases and Ageing Group, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Clinical Sciences Department, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Carrillo-Linares+JL%22">Carrillo-Linares JL</searchLink>; Department of Internal Medicine, Virgen de la Victoria University Hospital, Málaga, Spain.<br /><searchLink fieldCode="AU" term="%22Robles-Marhuenda+Á%22">Robles-Marhuenda Á</searchLink>; Department of Internal Medicine, La Paz University Hospital, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Puchades+F%22">Puchades F</searchLink>; Department of Internal Medicine, University General Hospital of Valencia, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Pelaez+Ballesta+A%22">Pelaez Ballesta A</searchLink>; Department of Internal Medicine, Rafael Méndez University Hospital, Murcia, Spain.<br /><searchLink fieldCode="AU" term="%22López-Osle+N%22">López-Osle N</searchLink>; Department of Internal Medicine, Cruces University Hospital, Bizkaia, Spain.<br /><searchLink fieldCode="AU" term="%22Torralba-Cabeza+MÁ%22">Torralba-Cabeza MÁ</searchLink>; Unit for Rare Diseases, Internal Medicine Service, Lozano Blesa University Hospital, Zaragoza, Spain.<br /><searchLink fieldCode="AU" term="%22Bielsa+Masdeu+AM%22">Bielsa Masdeu AM</searchLink>; Department of Internal Medicine, Miguel Servet University Hospital, Zaragoza, Spain.<br /><searchLink fieldCode="AU" term="%22Gil+Niño+J%22">Gil Niño J</searchLink>; Immunodeficiencies Clinic, Internal Medicine Department, 12 de Octubre Hospital, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Tornador+Gaya+N%22">Tornador Gaya N</searchLink>; Department of Internal Medicine, University General Hospital of Castellón, Castellón, Spain.<br /><searchLink fieldCode="AU" term="%22Pascual+Castellanos+G%22">Pascual Castellanos G</searchLink>; Department of Internal Medicine, University General Hospital of Castellón, Castellón, Spain.<br /><searchLink fieldCode="AU" term="%22Sánchez-Martínez+R%22">Sánchez-Martínez R</searchLink>; Internal Medicine Department, Dr. Balmis General University Hospital, Alicante Institute for Health and Biomedical Research, Alicante, Spain.<br /><searchLink fieldCode="AU" term="%22Barragán-Casas+JM%22">Barragán-Casas JM</searchLink>; Department of Internal Medicine, Complejo Asistencial de Ávila, Ávila, Spain.<br /><searchLink fieldCode="AU" term="%22González-García+A%22">González-García A</searchLink>; Systemic Autoimmune Diseases Unit, Internal Medicine Service, Ramón y Cajal Hospital, Ramón y Cajal Health Research Institute, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Patier+de+la+Peña+JL%22">Patier de la Peña JL</searchLink>; Department of Internal Medicine, University Hospital Alcorcón Foundation, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22López-Wolf+D%22">López-Wolf D</searchLink>; Department of Internal Medicine, General University Hospital of Elche, Alicante, Spain.<br /><searchLink fieldCode="AU" term="%22Mora+Rufete+A%22">Mora Rufete A</searchLink>; Department of Internal Medicine, General University Hospital of Elche, Alicante, Spain.<br /><searchLink fieldCode="AU" term="%22Canovas+Mora+A%22">Canovas Mora A</searchLink>; Department of Internal Medicine, General University Hospital of Elche, Alicante, Spain.<br /><searchLink fieldCode="AU" term="%22Cabañero-Navalon+MD%22">Cabañero-Navalon MD</searchLink>; Primary Immunodeficiencies Unit, Department of Internal Medicine, University and Polytechnic Hospital La Fe, Valencia, Spain.; Research Group of Chronic Diseases and HIV Infection, Health Research Institute La Fe, Valencia, Spain.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2025 Jul 23; Vol. 16, pp. 1640290. <i>Date of Electronic Publication: </i>2025 Jul 23 (<i>Print Publication: </i>2025).
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