Longitudinal single-cell analysis of glucagon-like peptide-2 treatment in patients with short bowel syndrome.

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Title: Longitudinal single-cell analysis of glucagon-like peptide-2 treatment in patients with short bowel syndrome.
Authors: Kudo Y; Department of Pediatric Surgery, and., Miyamoto K; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.; Research Department, R&D Division, Miyarisan Pharmaceutical Co., Ltd., Saitama, Japan., Suzuki S; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan., Chida A; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan., Tojo A; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan., Hasegawa M; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan., Shigehara A; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan., Koya I; Laboratory for Regulatory Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Ando Y; Laboratory for Regulatory Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Sato M; Department of Pediatric Surgery, and., Kondo A; Department of Pediatric Surgery, and., Kumagai T; Department of Pediatric Surgery, and., Deguchi H; Department of Pediatric Surgery, and., Sugiyama Y; Department of Pediatric Surgery, and., Ito Y; Department of Pediatric Surgery, and., Shirosaki K; Department of Pediatric Surgery, and., Yamagishi S; Department of Pediatric Surgery, and., Maeda Y; Department of Pediatric Surgery, and., Kanamori H; Department of Pediatric Surgery, and.; Department of Pediatric Surgery, Tokyo Metropolitan Children's Medical Center, Fuchu-shi, Tokyo, Japan., Kano M; Department of Pediatric Surgery, and., Kato M; Department of Pediatric Surgery, and., Tsujikawa H; Department of Pathology, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.; Department of Diagnostic Pathology, National Hospital Organization Saitama Hospital, Wako-shi, Saitama, Japan., Yoshimatsu Y; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan., Takabayashi K; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan., Okabayashi K; Department of Surgery, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan., Kanai T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan., Hosoe N; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan., Kato M; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan., Moody J; Laboratory for Regulatory Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Hon CC; Laboratory for Regulatory Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Kuroda T; Department of Pediatric Surgery, and.; Kanagawa Children's Medical Center, Yokohama, Kanagawa, Japan., Yamada Y; Department of Pediatric Surgery, and., Fujino A; Department of Pediatric Surgery, and., Sujino T; Department of Multidimensional Analysis of Gastrointestinal Biology, Sakaguchi Laboratory, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.; Keio Global Research Institute, Keio University, Mita, Minato-ku, Tokyo, Japan.
Source: JCI insight [JCI Insight] 2025 Aug 07; Vol. 10 (18). Date of Electronic Publication: 2025 Aug 07 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Kudo+Y%22">Kudo Y</searchLink>; Department of Pediatric Surgery, and.<br /><searchLink fieldCode="AU" term="%22Miyamoto+K%22">Miyamoto K</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.; Research Department, R&D Division, Miyarisan Pharmaceutical Co., Ltd., Saitama, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+S%22">Suzuki S</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Chida+A%22">Chida A</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tojo+A%22">Tojo A</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hasegawa+M%22">Hasegawa M</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Shigehara+A%22">Shigehara A</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Koya+I%22">Koya I</searchLink>; Laboratory for Regulatory Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Ando+Y%22">Ando Y</searchLink>; Laboratory for Regulatory Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Sato+M%22">Sato M</searchLink>; 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Department of Surgery, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kanai+T%22">Kanai T</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hosoe+N%22">Hosoe N</searchLink>; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+M%22">Kato M</searchLink>; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Moody+J%22">Moody J</searchLink>; Laboratory for Regulatory Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Hon+CC%22">Hon CC</searchLink>; Laboratory for Regulatory Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Kuroda+T%22">Kuroda T</searchLink>; 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