Ascending single-dose study of the safety, pharmacokinetics, and pharmacodynamics of CSTI-500, a novel monoamine triple reuptake inhibitor, first-in-human.
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| Title: | Ascending single-dose study of the safety, pharmacokinetics, and pharmacodynamics of CSTI-500, a novel monoamine triple reuptake inhibitor, first-in-human. |
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| Authors: | Appel L; Molecular Imaging and Medical Physics, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. lieuwe.appel@akademiska.se.; PET Centre, Department of Medical Imaging, Uppsala University Hospital, 75185, Uppsala, Sweden. lieuwe.appel@akademiska.se., Risinger R; BioXcel Therapeutics Inc., 555 Long Wharf Drive, New Haven, CT, 06511, USA., Wall A; Molecular Imaging and Medical Physics, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.; PET Centre, Department of Medical Imaging, Uppsala University Hospital, 75185, Uppsala, Sweden., Murck H; Philipps-University Marburg, Marburg, Germany.; Murck-Neuroscience LLC Westfield, Westfield, NJ, USA., Liu S; ConSynance Therapeutics, Inc., 11 University Place, Rensselaer, NY, 12144, USA., Antoni G; PET Centre, Department of Medical Imaging, Uppsala University Hospital, 75185, Uppsala, Sweden.; Department of Medical Chemistry, Uppsala University, Uppsala, Sweden., Lane R; Ionis Pharmaceuticals, Inc., 2855 Gazelle Court, Carlsbad, CA, 92010, USA. |
| Source: | Psychopharmacology [Psychopharmacology (Berl)] 2026 Mar; Vol. 243 (3), pp. 565-580. Date of Electronic Publication: 2025 Aug 11. |
| Publication Type: | Journal Article; Randomized Controlled Trial |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2072 (Electronic) Linking ISSN: 00333158 NLM ISO Abbreviation: Psychopharmacology (Berl) Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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