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Approaches to the Management of Virologic Failure on Dolutegravir-Based Antiretroviral Therapy in the 50 Countries With the Highest Adult HIV Prevalence.

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Title: Approaches to the Management of Virologic Failure on Dolutegravir-Based Antiretroviral Therapy in the 50 Countries With the Highest Adult HIV Prevalence.
Authors: Nutt CT; Medical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA., Lessells RJ; Department of Infectious Diseases, University of KwaZulu-Natal, Durban, South Africa.; KwaZulu-Natal Research Innovation and Sequencing Platform, University of KwaZulu-Natal, Durban, South Africa.; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa., Muyindike WR; Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda., Johnson LS; Medical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Kouyos RD; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Switzerland.; Institute of Medical Virology, University of Zurich, Zurich, Switzerland., Loosli T; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Switzerland.; Institute of Medical Virology, University of Zurich, Zurich, Switzerland., Ombajo LA; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya., Brijkumar J; Department of Infectious Diseases, University of KwaZulu-Natal, Durban, South Africa.; HIV, AIDS, STI, and TB Unit, RK Khan Hospital, Durban, South Africa., Hyle EP; Medical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA., Moosa MS; Department of Infectious Diseases, University of KwaZulu-Natal, Durban, South Africa., Gandhi M; Division of HIV, Infectious Diseases, and Global Medicine, University of California San Francisco, San Francisco, California, USA., Vitoria MAA; Global HIV, Hepatitis, and Sexually Transmitted Infections Programmes, World Health Organization, Geneva, Switzerland., Jordan MR; Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, Massachusetts, USA.; Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, Massachusetts, USA.; Global Health and Tropical Medicine, LA-REAL, Instituto de Higiene e Medicina Tropical, Universidade NOVA de Lisboa, Lisbon, Portugal., Siedner MJ; Medical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA.; Africa Health Research Institute, Durban, South Africa., McCluskey SM; Medical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA.
Source: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2026 Feb 25; Vol. 82 (2), pp. 265-273.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE; In Process
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  Data: <searchLink fieldCode="AU" term="%22Nutt+CT%22">Nutt CT</searchLink>; Medical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Lessells+RJ%22">Lessells RJ</searchLink>; Department of Infectious Diseases, University of KwaZulu-Natal, Durban, South Africa.; KwaZulu-Natal Research Innovation and Sequencing Platform, University of KwaZulu-Natal, Durban, South Africa.; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Muyindike+WR%22">Muyindike WR</searchLink>; Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Johnson+LS%22">Johnson LS</searchLink>; Medical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Kouyos+RD%22">Kouyos RD</searchLink>; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Switzerland.; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Loosli+T%22">Loosli T</searchLink>; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Switzerland.; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ombajo+LA%22">Ombajo LA</searchLink>; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya.<br /><searchLink fieldCode="AU" term="%22Brijkumar+J%22">Brijkumar J</searchLink>; Department of Infectious Diseases, University of KwaZulu-Natal, Durban, South Africa.; HIV, AIDS, STI, and TB Unit, RK Khan Hospital, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Hyle+EP%22">Hyle EP</searchLink>; Medical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Moosa+MS%22">Moosa MS</searchLink>; Department of Infectious Diseases, University of KwaZulu-Natal, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Gandhi+M%22">Gandhi M</searchLink>; Division of HIV, Infectious Diseases, and Global Medicine, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Vitoria+MAA%22">Vitoria MAA</searchLink>; Global HIV, Hepatitis, and Sexually Transmitted Infections Programmes, World Health Organization, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Jordan+MR%22">Jordan MR</searchLink>; Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, Massachusetts, USA.; Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, Massachusetts, USA.; Global Health and Tropical Medicine, LA-REAL, Instituto de Higiene e Medicina Tropical, Universidade NOVA de Lisboa, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Siedner+MJ%22">Siedner MJ</searchLink>; Medical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA.; Africa Health Research Institute, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22McCluskey+SM%22">McCluskey SM</searchLink>; Medical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA.
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