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Multiple oestradiol functions inhibit ferroptosis and acute kidney injury.

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Title: Multiple oestradiol functions inhibit ferroptosis and acute kidney injury.
Authors: Tonnus W; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany., Maremonti F; Department of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany., Gavali S; Department of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany., Schlecht MN; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany., Gembardt F; Department of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany., Belavgeni A; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany., Leinung N; Department of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany., Flade K; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany., Bethe N; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany., Traikov S; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany., Haag A; Chair of Organic Chemistry, Technische Universität Dresden, Dresden, Germany., Schilling D; Division of Redox Regulation, German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Penkov S; Center of Membrane Biochemistry and Lipid Research, University Hospital and Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Mallais M; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada., Gaillet C; Equipe Labellisée Ligue Contre le Cancer, Institut Curie, CNRS, INSERM, PSL Research University, Paris, France., Meyer C; Department of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany., Katebi M; Department of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany., Ray A; Department of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany., Gerhardt LMS; Department of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany., Brucker A; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany., Becker JN; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany., Tmava M; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany., Schlicker L; Division of Tumor Metabolism and Microenvironment, German Cancer Research Center (DKFZ), Heidelberg, Germany., Schulze A; Division of Tumor Metabolism and Microenvironment, German Cancer Research Center (DKFZ), Heidelberg, Germany., Himmerkus N; Institute of Physiology, Christian-Albrecht-University Kiel, Kiel, Germany., Shevchenko A; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany., Peitzsch M; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany., Barayeu U; Max Planck Institute for Polymer Research, Mainz, Germany., Nasi S; Service of Rheumatology, Department of Musculoskeletal Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland., Putz J; Clinic for Urology, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany., Korach KS; Laboratories of Reproductive and Developmental Toxicology, NIEHS, National Institutes of Health, Research Triangle Park, NC, USA., Neugarten J; Renal Division, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY, USA., Golestaneh L; Renal Division, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY, USA., Hugo C; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany., Becker JU; Institute of Pathology, University Hospital of Cologne, Cologne, Germany., Weinberg JM; Division for Nephrology, University of Michigan Medical Center, Ann Arbor, MI, USA., Lorenz S; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany., Proneth B; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany., Conrad M; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany., Wolf E; Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Munich, Germany.; Center for Innovative Medical Models (CiMM), LMU Munich, Oberschleißheim, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Plietker B; Chair of Organic Chemistry, Technische Universität Dresden, Dresden, Germany., Rodriguez R; Equipe Labellisée Ligue Contre le Cancer, Institut Curie, CNRS, INSERM, PSL Research University, Paris, France., Pratt DA; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada., Dick TP; Division of Redox Regulation, German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Fedorova M; Center of Membrane Biochemistry and Lipid Research, University Hospital and Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Bornstein SR; Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.; Diabetes and Nutritional Sciences, King's College London, London, UK.; Center for Regenerative Therapies, Technische Universität Dresden, Dresden, Germany.; Paul Langerhans Institute Dresden of Helmholtz Centre Munich at University Clinic Carl Gustav Carus of TU Dresden Faculty of Medicine, Dresden, Germany., Linkermann A; Department of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany. andreas.linkermann@medma.uni-heidelberg.de.; Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany. andreas.linkermann@medma.uni-heidelberg.de.; Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, New York, NY, USA. andreas.linkermann@medma.uni-heidelberg.de.
Source: Nature [Nature] 2025 Sep; Vol. 645 (8082), pp. 1011-1019. Date of Electronic Publication: 2025 Aug 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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