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Activation of PI3K and deletion of p53 in keratin 15-expressing mouse mammary cells induces tumor heterogeneity and plasticity modeling metaplastic breast cancer.

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Title: Activation of PI3K and deletion of p53 in keratin 15-expressing mouse mammary cells induces tumor heterogeneity and plasticity modeling metaplastic breast cancer.
Authors: Nguyen KA; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., McLemore LE; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Ke Y; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Department of Pathology & Laboratory Medicine, University of California Davis, Sacramento, CA, USA., DePledge LN; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Smith LP; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Bian L; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Aleman JD; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Debretsion D; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Wong E; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Manning N; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Wang XJ; Department of Pathology & Laboratory Medicine, University of California Davis, Sacramento, CA, USA.; VA Northern California Health Care System, Sacramento, CA, USA., Young CD; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Source: The Journal of pathology [J Pathol] 2025 Oct; Vol. 267 (2), pp. 213-224. Date of Electronic Publication: 2025 Aug 13.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 0204634 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9896 (Electronic) Linking ISSN: 00223417 NLM ISO Abbreviation: J Pathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Activation of PI3K and deletion of p53 in keratin 15-expressing mouse mammary cells induces tumor heterogeneity and plasticity modeling metaplastic breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Nguyen+KA%22">Nguyen KA</searchLink>; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22McLemore+LE%22">McLemore LE</searchLink>; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Ke+Y%22">Ke Y</searchLink>; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Department of Pathology & Laboratory Medicine, University of California Davis, Sacramento, CA, USA.<br /><searchLink fieldCode="AU" term="%22DePledge+LN%22">DePledge LN</searchLink>; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Smith+LP%22">Smith LP</searchLink>; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Bian+L%22">Bian L</searchLink>; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Aleman+JD%22">Aleman JD</searchLink>; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Debretsion+D%22">Debretsion D</searchLink>; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Wong+E%22">Wong E</searchLink>; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Manning+N%22">Manning N</searchLink>; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Wang+XJ%22">Wang XJ</searchLink>; Department of Pathology & Laboratory Medicine, University of California Davis, Sacramento, CA, USA.; VA Northern California Health Care System, Sacramento, CA, USA.<br /><searchLink fieldCode="AU" term="%22Young+CD%22">Young CD</searchLink>; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
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  Data: <searchLink fieldCode="JN" term="%220204634%22">The Journal of pathology</searchLink> [J Pathol] 2025 Oct; Vol. 267 (2), pp. 213-224. <i>Date of Electronic Publication: </i>2025 Aug 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+And+Sons%22">John Wiley And Sons </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0204634 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-9896 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200223417%22">00223417 </searchLink><i>NLM ISO Abbreviation: </i>J Pathol <i>Subsets: </i>MEDLINE
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        Value: 10.1002/path.6463
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              Text: 2025 Oct
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