Tecovirimat is active against various MPXV strains, while cidofovir, brincidofovir, trifluridine, and gemcitabine have no detectable MPXV-specific antiviral activity.
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| Title: | Tecovirimat is active against various MPXV strains, while cidofovir, brincidofovir, trifluridine, and gemcitabine have no detectable MPXV-specific antiviral activity. |
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| Authors: | Higashi-Kuwata N; Department of Refractory Viral Diseases, National Institute of Global Health and Medicine, Japan Institute for Health Security, Shinjuku-Ku, Tokyo 162-8655, Japan. Electronic address: kuwata.n@jihs.go.jp., Kato M; Department of Refractory Viral Diseases, National Institute of Global Health and Medicine, Japan Institute for Health Security, Shinjuku-Ku, Tokyo 162-8655, Japan., Hattori SI; Department of Refractory Viral Diseases, National Institute of Global Health and Medicine, Japan Institute for Health Security, Shinjuku-Ku, Tokyo 162-8655, Japan., Takamatsu Y; Department of Refractory Viral Diseases, National Institute of Global Health and Medicine, Japan Institute for Health Security, Shinjuku-Ku, Tokyo 162-8655, Japan., Mitsuya H; Department of Refractory Viral Diseases, National Institute of Global Health and Medicine, Japan Institute for Health Security, Shinjuku-Ku, Tokyo 162-8655, Japan; Kumamoto University Hospital, Kumamoto, 860-8556, Japan; Experimental Retrovirology Section, National Cancer Institute, NIH, Bethesda, MD, USA. Electronic address: hiroaki.mitsuya2@nih.gov. |
| Source: | Virus research [Virus Res] 2025 Oct; Vol. 360, pp. 199615. Date of Electronic Publication: 2025 Aug 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8410979 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7492 (Electronic) Linking ISSN: 01681702 NLM ISO Abbreviation: Virus Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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