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Respiration defects limit serine synthesis required for lung cancer growth and survival.

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Title: Respiration defects limit serine synthesis required for lung cancer growth and survival.
Authors: Cararo Lopes E; Rutgers Cancer Institute, New Brunswick, NJ, USA. edu.llopes@gmail.com.; Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ, USA. edu.llopes@gmail.com., Shi F; Rutgers Cancer Institute, New Brunswick, NJ, USA., Sawant A; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Ludwig Princeton Branch, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA., Ibrahim M; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Ludwig Princeton Branch, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA., Gomez-Jenkins M; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Ludwig Princeton Branch, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA., Hu Z; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Ludwig Princeton Branch, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA., Manchiraju P; Rutgers Cancer Institute, New Brunswick, NJ, USA., Bhatt V; Rutgers Cancer Institute, New Brunswick, NJ, USA., Wang W; Rutgers Cancer Institute, New Brunswick, NJ, USA., Hinrichs CS; Rutgers Cancer Institute, New Brunswick, NJ, USA., Wallace DC; Center for Mitochondrial and Epigenomic Medicine, the Children's Hospital of Philadelphia and Department of Pediatrics, Division of Human Genetics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Su X; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA., Rabinowitz JD; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Ludwig Princeton Branch, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA.; Department of Chemistry, Princeton University, Princeton, NJ, USA.; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ, USA., Chan CS; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA., Guo JY; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA.; Department of Chemical Biology, Rutgers Ernest Mario School of Pharmacy, Piscataway, NJ, USA., Ganesan S; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA., Lattime EC; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Department of Surgery, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA., White E; Rutgers Cancer Institute, New Brunswick, NJ, USA. epwhite@cinj.rutgers.edu.; Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ, USA. epwhite@cinj.rutgers.edu.; Ludwig Princeton Branch, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA. epwhite@cinj.rutgers.edu.
Source: Nature communications [Nat Commun] 2025 Aug 15; Vol. 16 (1), pp. 7621. Date of Electronic Publication: 2025 Aug 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Cararo+Lopes+E%22">Cararo Lopes E</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA. edu.llopes@gmail.com.; Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ, USA. edu.llopes@gmail.com.<br /><searchLink fieldCode="AU" term="%22Shi+F%22">Shi F</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Sawant+A%22">Sawant A</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Ludwig Princeton Branch, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Ibrahim+M%22">Ibrahim M</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Ludwig Princeton Branch, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Gomez-Jenkins+M%22">Gomez-Jenkins M</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Ludwig Princeton Branch, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Hu+Z%22">Hu Z</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Ludwig Princeton Branch, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Manchiraju+P%22">Manchiraju P</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Bhatt+V%22">Bhatt V</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Hinrichs+CS%22">Hinrichs CS</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Wallace+DC%22">Wallace DC</searchLink>; Center for Mitochondrial and Epigenomic Medicine, the Children's Hospital of Philadelphia and Department of Pediatrics, Division of Human Genetics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Su+X%22">Su X</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Rabinowitz+JD%22">Rabinowitz JD</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Ludwig Princeton Branch, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA.; Department of Chemistry, Princeton University, Princeton, NJ, USA.; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Chan+CS%22">Chan CS</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Guo+JY%22">Guo JY</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA.; Department of Chemical Biology, Rutgers Ernest Mario School of Pharmacy, Piscataway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Ganesan+S%22">Ganesan S</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Lattime+EC%22">Lattime EC</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA.; Department of Surgery, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA.<br /><searchLink fieldCode="AU" term="%22White+E%22">White E</searchLink>; Rutgers Cancer Institute, New Brunswick, NJ, USA. epwhite@cinj.rutgers.edu.; Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ, USA. epwhite@cinj.rutgers.edu.; Ludwig Princeton Branch, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA. epwhite@cinj.rutgers.edu.
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