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Localised delivery of interleukin-13 from a PLGA microparticle embedded GelMA hydrogel improves functional and histopathological recovery in a mouse contusion spinal cord injury model.

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Title: Localised delivery of interleukin-13 from a PLGA microparticle embedded GelMA hydrogel improves functional and histopathological recovery in a mouse contusion spinal cord injury model.
Authors: Walsh CM; School of Medicine, Health Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland.; UCD Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland., Colbert R; School of Medicine, Health Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland.; UCD Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland., Reynolds JP; School of Medicine, Health Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland.; UCD Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland., Dunne E; School of Medicine, Health Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland., Aiyegbusi ED; School of Medicine, Health Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland.; UCD Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland., O'Carroll R; School of Medicine, Health Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland.; Department of Histopathology, University Hospital Galway, Ireland., Wychowaniec JK; School of Chemistry, University College Dublin, Belfield, Dublin 4, Ireland.; AO Research Institute Davos, Clavadelerstrasse 8, Davos, 7270, Switzerland., Masuda T; Division of Molecular Neuroimmunology, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan., Knobeloch KP; Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany., Prinz M; Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany., Brougham DF; School of Chemistry, University College Dublin, Belfield, Dublin 4, Ireland., Dooley D; School of Medicine, Health Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland.; UCD Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.
Source: Bioactive materials [Bioact Mater] 2025 Aug 08; Vol. 53, pp. 855-874. Date of Electronic Publication: 2025 Aug 08 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Ke Ai Publishing Country of Publication: China NLM ID: 101685294 Publication Model: eCollection Cited Medium: Internet ISSN: 2452-199X (Electronic) Linking ISSN: 2452199X NLM ISO Abbreviation: Bioact Mater Subsets: PubMed not MEDLINE
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  Data: Localised delivery of interleukin-13 from a PLGA microparticle embedded GelMA hydrogel improves functional and histopathological recovery in a mouse contusion spinal cord injury model.
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