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Innovative simvastatin-loaded emulgel effectively treats vulvovaginal candidiasis: in vivo efficacy and in vitro biopharmaceutical analysis.

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Title: Innovative simvastatin-loaded emulgel effectively treats vulvovaginal candidiasis: in vivo efficacy and in vitro biopharmaceutical analysis.
Authors: Amorim MES; 'Dona Lindu' Midwest Campus, Universidade Federal de São João del-Rei (UFSJ), MG, 35501-296, Divinópolis, Brazil., Ribeiro NOL; 'Dona Lindu' Midwest Campus, Universidade Federal de São João del-Rei (UFSJ), MG, 35501-296, Divinópolis, Brazil., Pinto FCH; Department of Natural Sciences, Dom Bosco Campus, Universidade Federal de São João del-Rei (UFSJ), Divinópolis, MG, Brazil., de Oliveira PF; 'Dona Lindu' Midwest Campus, Universidade Federal de São João del-Rei (UFSJ), MG, 35501-296, Divinópolis, Brazil., Pommini MV; UNAERP, Ribeirão Preto, SP, Brazil., Siqueira MB; 'Dona Lindu' Midwest Campus, Universidade Federal de São João del-Rei (UFSJ), MG, 35501-296, Divinópolis, Brazil., Bello ZM; 'Dona Lindu' Midwest Campus, Universidade Federal de São João del-Rei (UFSJ), MG, 35501-296, Divinópolis, Brazil.; Department of Medical Laboratory Science, College of Medical Sciences, Ahmadu Bello University, Zaria, Nigeria., Fabri RL; Bioactive Natural Products Laboratory, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de For a (UFJF), Juiz de Fora, MG, Brazil., de Freitas MG; 'Dona Lindu' Midwest Campus, Universidade Federal de São João del-Rei (UFSJ), MG, 35501-296, Divinópolis, Brazil., do Couto RO; 'Dona Lindu' Midwest Campus, Universidade Federal de São João del-Rei (UFSJ), MG, 35501-296, Divinópolis, Brazil. rocouto@ufsj.edu.br.
Source: Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] [Braz J Microbiol] 2025 Dec; Vol. 56 (4), pp. 2687-2702. Date of Electronic Publication: 2025 Aug 18.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Publishing Country of Publication: Brazil NLM ID: 101095924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1678-4405 (Electronic) Linking ISSN: 15178382 NLM ISO Abbreviation: Braz J Microbiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Innovative simvastatin-loaded emulgel effectively treats vulvovaginal candidiasis: in vivo efficacy and in vitro biopharmaceutical analysis.
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  Data: <searchLink fieldCode="AU" term="%22Amorim+MES%22">Amorim MES</searchLink>; 'Dona Lindu' Midwest Campus, Universidade Federal de São João del-Rei (UFSJ), MG, 35501-296, Divinópolis, Brazil.<br /><searchLink fieldCode="AU" term="%22Ribeiro+NOL%22">Ribeiro NOL</searchLink>; 'Dona Lindu' Midwest Campus, Universidade Federal de São João del-Rei (UFSJ), MG, 35501-296, Divinópolis, Brazil.<br /><searchLink fieldCode="AU" term="%22Pinto+FCH%22">Pinto FCH</searchLink>; Department of Natural Sciences, Dom Bosco Campus, Universidade Federal de São João del-Rei (UFSJ), Divinópolis, MG, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Oliveira+PF%22">de Oliveira PF</searchLink>; 'Dona Lindu' Midwest Campus, Universidade Federal de São João del-Rei (UFSJ), MG, 35501-296, Divinópolis, Brazil.<br /><searchLink fieldCode="AU" term="%22Pommini+MV%22">Pommini MV</searchLink>; UNAERP, Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Siqueira+MB%22">Siqueira MB</searchLink>; 'Dona Lindu' Midwest Campus, Universidade Federal de São João del-Rei (UFSJ), MG, 35501-296, Divinópolis, Brazil.<br /><searchLink fieldCode="AU" term="%22Bello+ZM%22">Bello ZM</searchLink>; 'Dona Lindu' Midwest Campus, Universidade Federal de São João del-Rei (UFSJ), MG, 35501-296, Divinópolis, Brazil.; Department of Medical Laboratory Science, College of Medical Sciences, Ahmadu Bello University, Zaria, Nigeria.<br /><searchLink fieldCode="AU" term="%22Fabri+RL%22">Fabri RL</searchLink>; Bioactive Natural Products Laboratory, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de For a (UFJF), Juiz de Fora, MG, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Freitas+MG%22">de Freitas MG</searchLink>; 'Dona Lindu' Midwest Campus, Universidade Federal de São João del-Rei (UFSJ), MG, 35501-296, Divinópolis, Brazil.<br /><searchLink fieldCode="AU" term="%22do+Couto+RO%22">do Couto RO</searchLink>; 'Dona Lindu' Midwest Campus, Universidade Federal de São João del-Rei (UFSJ), MG, 35501-296, Divinópolis, Brazil. rocouto@ufsj.edu.br.
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  Data: <searchLink fieldCode="JN" term="%22101095924%22">Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]</searchLink> [Braz J Microbiol] 2025 Dec; Vol. 56 (4), pp. 2687-2702. <i>Date of Electronic Publication: </i>2025 Aug 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International+Publishing%22">Springer International Publishing </searchLink><i>Country of Publication: </i>Brazil <i>NLM ID: </i>101095924 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1678-4405 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215178382%22">15178382 </searchLink><i>NLM ISO Abbreviation: </i>Braz J Microbiol <i>Subsets: </i>MEDLINE
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              Text: 2025 Dec
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