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Glioblastoma in adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions.

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Title: Glioblastoma in adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions.
Authors: Wen PY; Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Weller M; Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland., Lee EQ; Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Touat M; Service de Neuro-oncologie, Sorbonne Université, Inserm, CNRS, UMR S 1127, Institut du Cerveau, Paris Brain Institute, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Paris, France., Khasraw M; The Preston Robert Tisch Brain Tumor Center, Duke University, Durham, North Carolina, USA., Rahman R; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, USA., Platten M; Department of Neurology, Medical Faculty Mannheim, MCTN, Heidelberg University and German Cancer Research Center, DKTK, Heidelberg, Germany., Lim M; Department of Neurosurgery, Stanford University, Stanford, California, USA., Winkler F; National Center for Tumor Diseases, Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neurology, Heidelberg Medical Faculty of Heidelberg University, Heidelberg, Germany., Horbinski C; Department of Pathology, Northwestern University, Chicago, Illinois, USA., Verhaak RGW; Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut, USA., Huang RY; Division of Neuroradiology, Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Ahluwalia MS; Division of Medical Oncology, Baptist Health Miami Cancer Institute, Florida International University, Miami, Florida, USA., Albert NL; Department of Nuclear Medicine, LMU University Hospital, Ludwig Maximilians University Munich, Munich, Germany., Tonn JC; Department of Neurosurgery Klinikum Ludwig Maximilians University Munich, Munich, Germany., Schiff D; Division of Neuro-Oncology, Department of Neurology, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Barnholtz-Sloan JS; Center for Biomedical Informatics and Information Technology and Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Ostrom Q; Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina, USA., Aldape KD; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Batchelor TT; Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Bindra RS; Departments of Therapeutic Radiology, Pathology, and Neurosugery, Yale Medical School, New Haven, Connecticut, USA., Chiocca EA; Department of Neurosurgery, Mass General Brigham, Boston, Massachusetts, USA., Cloughesy TF; University of California, Los Angeles, Los Angeles, California, USA., DeGroot JF; Department of Neurology and Neurosurgery, University of California, San Francisco, San Francisco, California, USA., French P; Department of Neurology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Galanis E; Department of Oncology, Mayo Clinic, Rochester, Minnesota, USA., Galldiks N; Center of Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Germany.; Insitute of Neuroscience and Medicine (INM-3), Research Center Juelich, Juelich, Germany.; Department of Neurology, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Gilbert MR; National Institutes of Health, Bethesda, Maryland, USA., Hegi ME; Neuroscience Research Center and Service of Neurosurgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Lassman AB; Division of Neuro-Oncology, Department of Neurology, Columbia University Vagelos College of Physicians and Surgeons, and Herbert Irving Comprehensive Cancer Center, NewYork-Presbyterian, New York, New York, USA., Le Rhun E; Department of Medical Oncology and Hematology, and Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland., Mehta MP; Department of Radiation Oncology, Florida International University, Baptist Health, Miami Cancer Institute, Miami, Florida, USA., Mellinghoff IK; Department of Neurology and Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Minniti G; Department of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza and IRCCS Neuromed, Pozzilli, Italy., Roth P; Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland., Sanson M; Service de Neuro-oncologie, Sorbonne Université, Inserm, CNRS, UMR S 1127, Institut du Cerveau, Paris Brain Institute, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Paris, France., Taphoorn Andreas MJB; Department of Neurology, Leiden University Medical Center, The Netherlands., Weiss VDT; Department of Neuropathology, University Hospital Heidelberg, and CCU Neuropathology, German Cancer Center (DKFZ), Heidelberg, Germany., Wick W; Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland., Zadeh G; Neurology, University Clinic Heidelberg, Heidelberg University & German Cancer Consortium (DKTK) and CCU Neurooncology, German Cancer Research Center, Heidelberg, Germany., Reardon DA; Department of Neurologic Surgery, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA., Chang SM; Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Short SC; Department of Neurological Surgery, University of California, San Francisco, San Francisco California, USA., van den Bent MJ; Department of Oncology, St James's University Hospital and University of Leeds, Leeds, UK., Preusser M; Department of Neurology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.; Division of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Source: Neuro-oncology [Neuro Oncol] 2025 Nov 01; Vol. 27 (11), pp. 2751-2788.
Publication Type: Journal Article; Review
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Glioblastoma in adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions.
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  Data: <searchLink fieldCode="AU" term="%22Wen+PY%22">Wen PY</searchLink>; Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Weller+M%22">Weller M</searchLink>; Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lee+EQ%22">Lee EQ</searchLink>; Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Touat+M%22">Touat M</searchLink>; Service de Neuro-oncologie, Sorbonne Université, Inserm, CNRS, UMR S 1127, Institut du Cerveau, Paris Brain Institute, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Paris, France.<br /><searchLink fieldCode="AU" term="%22Khasraw+M%22">Khasraw M</searchLink>; The Preston Robert Tisch Brain Tumor Center, Duke University, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Rahman+R%22">Rahman R</searchLink>; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Platten+M%22">Platten M</searchLink>; Department of Neurology, Medical Faculty Mannheim, MCTN, Heidelberg University and German Cancer Research Center, DKTK, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lim+M%22">Lim M</searchLink>; Department of Neurosurgery, Stanford University, Stanford, California, USA.<br /><searchLink fieldCode="AU" term="%22Winkler+F%22">Winkler F</searchLink>; National Center for Tumor Diseases, Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neurology, Heidelberg Medical Faculty of Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Horbinski+C%22">Horbinski C</searchLink>; Department of Pathology, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Verhaak+RGW%22">Verhaak RGW</searchLink>; 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Center for Biomedical Informatics and Information Technology and Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Ostrom+Q%22">Ostrom Q</searchLink>; Department of Neurosurgery, Duke University School of Medicine, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Aldape+KD%22">Aldape KD</searchLink>; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Batchelor+TT%22">Batchelor TT</searchLink>; Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Bindra+RS%22">Bindra RS</searchLink>; Departments of Therapeutic Radiology, Pathology, and Neurosugery, Yale Medical School, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Chiocca+EA%22">Chiocca EA</searchLink>; Department of Neurosurgery, Mass General Brigham, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Cloughesy+TF%22">Cloughesy TF</searchLink>; University of California, Los Angeles, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22DeGroot+JF%22">DeGroot JF</searchLink>; Department of Neurology and Neurosurgery, University of California, San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22French+P%22">French P</searchLink>; Department of Neurology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Galanis+E%22">Galanis E</searchLink>; Department of Oncology, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Galldiks+N%22">Galldiks N</searchLink>; Center of Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Germany.; Insitute of Neuroscience and Medicine (INM-3), Research Center Juelich, Juelich, Germany.; Department of Neurology, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Gilbert+MR%22">Gilbert MR</searchLink>; National Institutes of Health, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Hegi+ME%22">Hegi ME</searchLink>; Neuroscience Research Center and Service of Neurosurgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lassman+AB%22">Lassman AB</searchLink>; Division of Neuro-Oncology, Department of Neurology, Columbia University Vagelos College of Physicians and Surgeons, and Herbert Irving Comprehensive Cancer Center, NewYork-Presbyterian, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Le+Rhun+E%22">Le Rhun E</searchLink>; Department of Medical Oncology and Hematology, and Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mehta+MP%22">Mehta MP</searchLink>; Department of Radiation Oncology, Florida International University, Baptist Health, Miami Cancer Institute, Miami, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Mellinghoff+IK%22">Mellinghoff IK</searchLink>; 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Department of Neuropathology, University Hospital Heidelberg, and CCU Neuropathology, German Cancer Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Wick+W%22">Wick W</searchLink>; Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zadeh+G%22">Zadeh G</searchLink>; Neurology, University Clinic Heidelberg, Heidelberg University & German Cancer Consortium (DKTK) and CCU Neurooncology, German Cancer Research Center, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Reardon+DA%22">Reardon DA</searchLink>; Department of Neurologic Surgery, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Chang+SM%22">Chang SM</searchLink>; Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Short+SC%22">Short SC</searchLink>; 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