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Discovery and Characterization of Uracil Derivatives Targeting the Set-and-Ring Domain of UHRF1.

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Title: Discovery and Characterization of Uracil Derivatives Targeting the Set-and-Ring Domain of UHRF1.
Authors: Akrani I; Division of Pharmaceutical Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece., Driva D; Division of Pharmaceutical Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece., Tsakalidis E; Division of Pharmaceutical Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece., Mozumdar N; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, Old Road Campus Research Building, OX3 7DQ, Oxford, United Kingdom., Mavridi D; Division of Pharmaceutical Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece., Panara A; Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece., Epiphaniou K; Division of Pharmaceutical Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece., Chalkiadaki M; Division of Pharmaceutical Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece., Wright AF; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, EH4 2XU, Edinburgh, United Kingdom., Halabalaki M; Division of Pharmaceutical Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece., Tsoka A; Department of Biology, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece., Zoidis G; Division of Pharmaceutical Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece., Vorgias C; Department of Biology, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece., Sproul D; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, EH4 2XU, Edinburgh, United Kingdom., Gikas E; Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece., Kriaucionis S; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, Old Road Campus Research Building, OX3 7DQ, Oxford, United Kingdom., Mikros E; Division of Pharmaceutical Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece., Myrianthopoulos V; Division of Pharmaceutical Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece.
Source: Journal of chemical information and modeling [J Chem Inf Model] 2025 Sep 08; Vol. 65 (17), pp. 9274-9286. Date of Electronic Publication: 2025 Aug 19.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE
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