The ILIA study: protocol for a randomized-controlled multicenter clinical trial on smartphone- and web-based relapse monitoring for patients with schizophrenia or schizoaffective disorder.

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Title: The ILIA study: protocol for a randomized-controlled multicenter clinical trial on smartphone- and web-based relapse monitoring for patients with schizophrenia or schizoaffective disorder.
Authors: Hiller S; Technical University of Munich, TUM School of Medicine and Health, Department of Psychiatry and Psychotherapy, TUM University Hospital, Munich, Germany. selina.hiller@tum.de., Emde L; Department of Psychiatry and Neuroscience, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany., Jais D; Department of Psychiatry and Neuroscience, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany., Sikorová SN; Mindpax.me, Prague, Czech Republic., Bakstein E; Mindpax.me, Prague, Czech Republic.; Center for first episodes of SMI, National Institute of Mental Health, Klecany, Czech Republic.; Analysis and interpretation of biomedical data, Faculty of Electrical Engineering, Prague, Czech Republic., Španiel F; Center for first episodes of SMI, National Institute of Mental Health, Klecany, Czech Republic.; Analysis and interpretation of biomedical data, Faculty of Electrical Engineering, Prague, Czech Republic., Urbanová K; Mindpax.me, Prague, Czech Republic.; Center for first episodes of SMI, National Institute of Mental Health, Klecany, Czech Republic.; Department of Psychology, Faculty of Arts, Charles University (SMI NUDZ), Prague, Czech Republic., Hahn E; Department of Psychiatry and Neuroscience, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.; DZPG (German Center for Mental Health), partner site Berlin, Berlin, Germany., Zierhut M; Department of Psychiatry and Neuroscience, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.; DZPG (German Center for Mental Health), partner site Berlin, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, BIH Charité Clinician Scientist Program, Berlin, Germany., Fürstenau D; School of Business & Economics, Freie Universität Berlin, Berlin, Germany.; Institute of Medical Informatics, Charité - Universitätsmedizin BerlinFreie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany., Bühner M; Department of Psychology, LMU Munich, Munich, Germany., Junker L; Department of Psychology, LMU Munich, Munich, Germany., Maurus I; Department for Psychiatry and Psychotherapy, LMU University Hospital, Munich, Germany., Pogarell O; Department for Psychiatry and Psychotherapy, LMU University Hospital, Munich, Germany., Falkai P; Department for Psychiatry and Psychotherapy, LMU University Hospital, Munich, Germany.; Max-Planck-Institute for Psychiatry, Munich, Germany.; DZPG (German Center for Mental Health), partner site Munich/Augsburg, Munich, Germany., Strube W; Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, University of Augsburg, Augsburg, Germany., Bauer I; Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, University of Augsburg, Augsburg, Germany., Skuban-Eiseler T; kbo-Isar-Amper-Klinikum Region München, München-Haar, Germany.; Institute of the History, Philosophy and Ethics of Medicine, Faculty of Medicine, Ulm University, Ulm, Germany., Priller J; Technical University of Munich, TUM School of Medicine and Health, Department of Psychiatry and Psychotherapy, TUM University Hospital, Munich, Germany.; DZPG (German Center for Mental Health), partner site Munich/Augsburg, Munich, Germany., Brieger P; kbo-Isar-Amper-Klinikum Region München, München-Haar, Germany., Heres S; kbo-Isar-Amper-Klinikum Region München, München-Haar, Germany., Hasan A; DZPG (German Center for Mental Health), partner site Munich/Augsburg, Munich, Germany.; Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, University of Augsburg, Augsburg, Germany., Böge K; Department of Psychiatry and Neuroscience, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.; DZPG (German Center for Mental Health), partner site Berlin, Berlin, Germany.; Department for Psychology, Medical University Brandenburg, Neuruppin, Germany., Leucht S; Technical University of Munich, TUM School of Medicine and Health, Department of Psychiatry and Psychotherapy, TUM University Hospital, Munich, Germany.; DZPG (German Center for Mental Health), partner site Munich/Augsburg, Munich, Germany.
Source: European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2026 Mar; Vol. 276 (2), pp. 637-650. Date of Electronic Publication: 2025 Aug 19.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9103030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-8491 (Electronic) Linking ISSN: 09401334 NLM ISO Abbreviation: Eur Arch Psychiatry Clin Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The ILIA study: protocol for a randomized-controlled multicenter clinical trial on smartphone- and web-based relapse monitoring for patients with schizophrenia or schizoaffective disorder.
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  Data: <searchLink fieldCode="AU" term="%22Hiller+S%22">Hiller S</searchLink>; Technical University of Munich, TUM School of Medicine and Health, Department of Psychiatry and Psychotherapy, TUM University Hospital, Munich, Germany. selina.hiller@tum.de.<br /><searchLink fieldCode="AU" term="%22Emde+L%22">Emde L</searchLink>; Department of Psychiatry and Neuroscience, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Jais+D%22">Jais D</searchLink>; Department of Psychiatry and Neuroscience, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Sikorová+SN%22">Sikorová SN</searchLink>; Mindpax.me, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Bakstein+E%22">Bakstein E</searchLink>; Mindpax.me, Prague, Czech Republic.; Center for first episodes of SMI, National Institute of Mental Health, Klecany, Czech Republic.; Analysis and interpretation of biomedical data, Faculty of Electrical Engineering, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Španiel+F%22">Španiel F</searchLink>; Center for first episodes of SMI, National Institute of Mental Health, Klecany, Czech Republic.; Analysis and interpretation of biomedical data, Faculty of Electrical Engineering, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Urbanová+K%22">Urbanová K</searchLink>; Mindpax.me, Prague, Czech Republic.; Center for first episodes of SMI, National Institute of Mental Health, Klecany, Czech Republic.; Department of Psychology, Faculty of Arts, Charles University (SMI NUDZ), Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Hahn+E%22">Hahn E</searchLink>; Department of Psychiatry and Neuroscience, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.; DZPG (German Center for Mental Health), partner site Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Zierhut+M%22">Zierhut M</searchLink>; Department of Psychiatry and Neuroscience, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.; DZPG (German Center for Mental Health), partner site Berlin, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, BIH Charité Clinician Scientist Program, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Fürstenau+D%22">Fürstenau D</searchLink>; School of Business & Economics, Freie Universität Berlin, Berlin, Germany.; Institute of Medical Informatics, Charité - Universitätsmedizin BerlinFreie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Bühner+M%22">Bühner M</searchLink>; Department of Psychology, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Junker+L%22">Junker L</searchLink>; Department of Psychology, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Maurus+I%22">Maurus I</searchLink>; Department for Psychiatry and Psychotherapy, LMU University Hospital, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Pogarell+O%22">Pogarell O</searchLink>; Department for Psychiatry and Psychotherapy, LMU University Hospital, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Falkai+P%22">Falkai P</searchLink>; Department for Psychiatry and Psychotherapy, LMU University Hospital, Munich, Germany.; Max-Planck-Institute for Psychiatry, Munich, Germany.; DZPG (German Center for Mental Health), partner site Munich/Augsburg, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Strube+W%22">Strube W</searchLink>; Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, University of Augsburg, Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Bauer+I%22">Bauer I</searchLink>; Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, University of Augsburg, Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Skuban-Eiseler+T%22">Skuban-Eiseler T</searchLink>; kbo-Isar-Amper-Klinikum Region München, München-Haar, Germany.; Institute of the History, Philosophy and Ethics of Medicine, Faculty of Medicine, Ulm University, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Priller+J%22">Priller J</searchLink>; Technical University of Munich, TUM School of Medicine and Health, Department of Psychiatry and Psychotherapy, TUM University Hospital, Munich, Germany.; DZPG (German Center for Mental Health), partner site Munich/Augsburg, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Brieger+P%22">Brieger P</searchLink>; kbo-Isar-Amper-Klinikum Region München, München-Haar, Germany.<br /><searchLink fieldCode="AU" term="%22Heres+S%22">Heres S</searchLink>; kbo-Isar-Amper-Klinikum Region München, München-Haar, Germany.<br /><searchLink fieldCode="AU" term="%22Hasan+A%22">Hasan A</searchLink>; DZPG (German Center for Mental Health), partner site Munich/Augsburg, Munich, Germany.; Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, University of Augsburg, Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Böge+K%22">Böge K</searchLink>; Department of Psychiatry and Neuroscience, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.; DZPG (German Center for Mental Health), partner site Berlin, Berlin, Germany.; Department for Psychology, Medical University Brandenburg, Neuruppin, Germany.<br /><searchLink fieldCode="AU" term="%22Leucht+S%22">Leucht S</searchLink>; Technical University of Munich, TUM School of Medicine and Health, Department of Psychiatry and Psychotherapy, TUM University Hospital, Munich, Germany.; DZPG (German Center for Mental Health), partner site Munich/Augsburg, Munich, Germany.
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  Data: <searchLink fieldCode="JN" term="%229103030%22">European archives of psychiatry and clinical neuroscience</searchLink> [Eur Arch Psychiatry Clin Neurosci] 2026 Mar; Vol. 276 (2), pp. 637-650. <i>Date of Electronic Publication: </i>2025 Aug 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International%22">Springer International </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9103030 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1433-8491 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209401334%22">09401334 </searchLink><i>NLM ISO Abbreviation: </i>Eur Arch Psychiatry Clin Neurosci <i>Subsets: </i>MEDLINE
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