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Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits.

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Title: Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits.
Authors: Johnson EC; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA., Lai D; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA., Balbona JV; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA., Miller AP; Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA., Hatoum AS; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA., Deak JD; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, CT, USA., Jennings M; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA., Baranger DAA; Department of Psychological and Brain Sciences, Washington University in St Louis, Saint Louis, MO, USA., Galimberti M; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, CT, USA.; Department of Human Genetics, Yale University School of Medicine, New Haven, CT, USA., Sanichwankul K; Suanprung Psychiatric Hospital, Chiang Mai, Thailand., Thorgeirsson T; deCODE Genetics/Amgen, Sturlugata 8, IS-101, Reykjavik, Iceland., Colbert SMC; Department of Genetics and Genomic Sciences, https://ror.org/04a9tmd77Icahn School of Medicine at Mount Sinai, New York, NY, USA., Adhikari K; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, CT, USA.; Department of Human Genetics, Yale University School of Medicine, New Haven, CT, USA., Docherty AR; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT, USA., Degenhardt L; National Drug and Alcohol Research Centre, https://ror.org/03r8z3t63University of New South Wales, Sydney, Australia., Edwards T; Department of Psychology, https://ror.org/017zqws13University of Minnesota Twin Cities, Minneapolis, MN, USA., Fox L; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA., Giannelis A; Department of Psychology, https://ror.org/017zqws13University of Minnesota Twin Cities, Minneapolis, MN, USA., Jeffries PW; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA., Korhonen T; Institute for Molecular Medicine Finland, https://ror.org/040af2s02University of Helsinki, Helsinki, Finland., Morrison CL; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA., Nunez YZ; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, CT, USA.; Department of Human Genetics, Yale University School of Medicine, New Haven, CT, USA., Palviainen T; Institute for Molecular Medicine Finland, https://ror.org/040af2s02University of Helsinki, Helsinki, Finland., Su MH; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA., Romero Villela PN; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA., Wetherill L; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA., Willoughby EA; Department of Psychology, https://ror.org/017zqws13University of Minnesota Twin Cities, Minneapolis, MN, USA., Zellers SM; Institute for Molecular Medicine Finland, https://ror.org/040af2s02University of Helsinki, Helsinki, Finland., Bierut LJ; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA., Buchwald J; Institute for Molecular Medicine Finland, https://ror.org/040af2s02University of Helsinki, Helsinki, Finland., Copeland WE; Department of Psychiatry, College of Medicine, University of Vermont, Burlington, VT, USA., Corley RP; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA., Friedman NP; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA., Foroud TM; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA., Gillespie NA; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Gizer IR; Department of Psychological Sciences, https://ror.org/02ymw8z06University of Missouri, Columbia, MO, USA., Heath AC; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA., Hickie IB; Brain and Mind Institute, https://ror.org/0384j8v12University of Sydney, Sydney, NSW, Australia., Kaprio J; Institute for Molecular Medicine Finland, https://ror.org/040af2s02University of Helsinki, Helsinki, Finland., Keller MC; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA., Lee JJ; Department of Psychology, https://ror.org/017zqws13University of Minnesota Twin Cities, Minneapolis, MN, USA., Lind P; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.; School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia., Madden PA; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA., Maes HHM; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.; Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, USA.; Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., McGue M; Department of Psychology, https://ror.org/017zqws13University of Minnesota Twin Cities, Minneapolis, MN, USA., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Psychology and Counselling, Queensland University of Technology, Brisbane, Australia.; School of Psychology, University of Queensland, Brisbane, Australia., Nelson EC; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA., Pearson J; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, Australia., Porjesz B; Henri Begleiter Neurodynamics Laboratory, Department of Psychiatry, SUNY Downstate Health Science University, Brooklyn, NY, USA., Stallings MC; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA., Vrieze S; Department of Psychology, https://ror.org/017zqws13University of Minnesota Twin Cities, Minneapolis, MN, USA., Wilhelmson KC; Department of Neurology and Genetics and the Bowles Center of Alcohol Studies, University of North Carolina, Chapel Hill, NC, USA.; Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, USA.; Renaissance Computing Institute, Chapel Hill, NC, USA., Kranzler HR; Mental Illness Research, Education and Clinical Center, Crescenz VAMC, Philadelphia, PA, USA.; Center for Studies of Addiction, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Walters RK; Analytic and Translational Genetics Unit, https://ror.org/002pd6e78Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Polimanti R; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Cooperative Studies Program Clinical Epidemiology Research Center (CSP-CERC), VA Connecticut Healthcare System, West Haven, CT, USA.; Wu Tsai Institute, Yale University, New Haven, CT, USA., Malison R; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; The Clinical Neuroscience Research Unit, Connecticut Mental Health Center, New Haven, CT, USA., Zhou H; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, CT, USA., Stefansson K; deCODE Genetics/Amgen, Sturlugata 8, IS-101, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Sanchez-Roige S; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA.; Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Potenza M; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Wu Tsai Institute, Yale University, New Haven, CT, USA.; Child Study Center, Yale School of Medicine, New Haven, CT, USA.; Connecticut Council on Problem Gambling, Wethersfield, CT, USA.; Connecticut Mental Health Center, New Haven, CT, USA., Mutirangura A; Department of Anatomy, Faculty of Medicine, https://ror.org/028wp3y58Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand., Shotelersuk V; Center of Excellence for Medical Genomics, Department of Pediatrics, Faculty of Medicine, https://ror.org/028wp3y58Chulalongkorn University, Bangkok, Thailand.; Excellence Center for Genomics and Precision Medicine, King Chulalongkorn Memorial Hospital, the Thai Red Cross Society, Bangkok, Thailand., Kalayasiri R; Department of Psychiatry, Epidemiology of Psychiatric Disorders and Mental Health Research Unit, Faculty of Medicine, https://ror.org/028wp3y58Chulalongkorn University, Bangkok, Thailand.; Department of Psychiatry, King Chulalongkorn Memorial Hospital, Bangkok, Thailand., Edenberg HJ; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA., Gelernter J; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, CT, USA.; Department of Human Genetics, Yale University School of Medicine, New Haven, CT, USA.; Department of Neuroscience, Yale University School of Medicine, New Haven, CT, USA., Agrawal A; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA.
Source: Psychological medicine [Psychol Med] 2025 Aug 20; Vol. 55, pp. e234. Date of Electronic Publication: 2025 Aug 20.
Publication Type: Journal Article
Journal Info: Publisher: Cambridge University Press Country of Publication: England NLM ID: 1254142 Publication Model: Electronic Cited Medium: Internet ISSN: 1469-8978 (Electronic) Linking ISSN: 00332917 NLM ISO Abbreviation: Psychol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits.
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  Data: <searchLink fieldCode="AU" term="%22Johnson+EC%22">Johnson EC</searchLink>; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Lai+D%22">Lai D</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Balbona+JV%22">Balbona JV</searchLink>; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Miller+AP%22">Miller AP</searchLink>; Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Hatoum+AS%22">Hatoum AS</searchLink>; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Deak+JD%22">Deak JD</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Jennings+M%22">Jennings M</searchLink>; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Baranger+DAA%22">Baranger DAA</searchLink>; Department of Psychological and Brain Sciences, Washington University in St Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Galimberti+M%22">Galimberti M</searchLink>; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, CT, USA.; Department of Human Genetics, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Sanichwankul+K%22">Sanichwankul K</searchLink>; Suanprung Psychiatric Hospital, Chiang Mai, Thailand.<br /><searchLink fieldCode="AU" term="%22Thorgeirsson+T%22">Thorgeirsson T</searchLink>; deCODE Genetics/Amgen, Sturlugata 8, IS-101, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Colbert+SMC%22">Colbert SMC</searchLink>; Department of Genetics and Genomic Sciences, https://ror.org/04a9tmd77Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Adhikari+K%22">Adhikari K</searchLink>; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, CT, USA.; Department of Human Genetics, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Docherty+AR%22">Docherty AR</searchLink>; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Degenhardt+L%22">Degenhardt L</searchLink>; National Drug and Alcohol Research Centre, https://ror.org/03r8z3t63University of New South Wales, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Edwards+T%22">Edwards T</searchLink>; Department of Psychology, https://ror.org/017zqws13University of Minnesota Twin Cities, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Fox+L%22">Fox L</searchLink>; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Giannelis+A%22">Giannelis A</searchLink>; Department of Psychology, https://ror.org/017zqws13University of Minnesota Twin Cities, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Jeffries+PW%22">Jeffries PW</searchLink>; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Korhonen+T%22">Korhonen T</searchLink>; Institute for Molecular Medicine Finland, https://ror.org/040af2s02University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Morrison+CL%22">Morrison CL</searchLink>; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Nunez+YZ%22">Nunez YZ</searchLink>; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, CT, USA.; Department of Human Genetics, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Palviainen+T%22">Palviainen T</searchLink>; Institute for Molecular Medicine Finland, https://ror.org/040af2s02University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Su+MH%22">Su MH</searchLink>; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Romero+Villela+PN%22">Romero Villela PN</searchLink>; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Wetherill+L%22">Wetherill L</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Willoughby+EA%22">Willoughby EA</searchLink>; Department of Psychology, https://ror.org/017zqws13University of Minnesota Twin Cities, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Zellers+SM%22">Zellers SM</searchLink>; Institute for Molecular Medicine Finland, https://ror.org/040af2s02University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Bierut+LJ%22">Bierut LJ</searchLink>; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Buchwald+J%22">Buchwald J</searchLink>; Institute for Molecular Medicine Finland, https://ror.org/040af2s02University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Copeland+WE%22">Copeland WE</searchLink>; Department of Psychiatry, College of Medicine, University of Vermont, Burlington, VT, USA.<br /><searchLink fieldCode="AU" term="%22Corley+RP%22">Corley RP</searchLink>; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Friedman+NP%22">Friedman NP</searchLink>; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Foroud+TM%22">Foroud TM</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Gillespie+NA%22">Gillespie NA</searchLink>; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Gizer+IR%22">Gizer IR</searchLink>; Department of Psychological Sciences, https://ror.org/02ymw8z06University of Missouri, Columbia, MO, USA.<br /><searchLink fieldCode="AU" term="%22Heath+AC%22">Heath AC</searchLink>; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Hickie+IB%22">Hickie IB</searchLink>; Brain and Mind Institute, https://ror.org/0384j8v12University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Kaprio+J%22">Kaprio J</searchLink>; Institute for Molecular Medicine Finland, https://ror.org/040af2s02University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Keller+MC%22">Keller MC</searchLink>; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Lee+JJ%22">Lee JJ</searchLink>; Department of Psychology, https://ror.org/017zqws13University of Minnesota Twin Cities, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Lind+P%22">Lind P</searchLink>; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.; School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Madden+PA%22">Madden PA</searchLink>; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Maes+HHM%22">Maes HHM</searchLink>; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.; Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, USA.; Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Martin+NG%22">Martin NG</searchLink>; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22McGue+M%22">McGue M</searchLink>; Department of Psychology, https://ror.org/017zqws13University of Minnesota Twin Cities, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Medland+SE%22">Medland SE</searchLink>; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Psychology and Counselling, Queensland University of Technology, Brisbane, Australia.; School of Psychology, University of Queensland, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Nelson+EC%22">Nelson EC</searchLink>; Department of Psychiatry, Washington University School of Medicine in St Louis, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Pearson+J%22">Pearson J</searchLink>; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Porjesz+B%22">Porjesz B</searchLink>; Henri Begleiter Neurodynamics Laboratory, Department of Psychiatry, SUNY Downstate Health Science University, Brooklyn, NY, USA.<br /><searchLink fieldCode="AU" term="%22Stallings+MC%22">Stallings MC</searchLink>; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Vrieze+S%22">Vrieze S</searchLink>; Department of Psychology, https://ror.org/017zqws13University of Minnesota Twin Cities, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Wilhelmson+KC%22">Wilhelmson KC</searchLink>; Department of Neurology and Genetics and the Bowles Center of Alcohol Studies, University of North Carolina, Chapel Hill, NC, USA.; Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, USA.; Renaissance Computing Institute, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Kranzler+HR%22">Kranzler HR</searchLink>; Mental Illness Research, Education and Clinical Center, Crescenz VAMC, Philadelphia, PA, USA.; Center for Studies of Addiction, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Walters+RK%22">Walters RK</searchLink>; Analytic and Translational Genetics Unit, https://ror.org/002pd6e78Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Polimanti+R%22">Polimanti R</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Cooperative Studies Program Clinical Epidemiology Research Center (CSP-CERC), VA Connecticut Healthcare System, West Haven, CT, USA.; Wu Tsai Institute, Yale University, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Malison+R%22">Malison R</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; The Clinical Neuroscience Research Unit, Connecticut Mental Health Center, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+H%22">Zhou H</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Stefansson+K%22">Stefansson K</searchLink>; deCODE Genetics/Amgen, Sturlugata 8, IS-101, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Sanchez-Roige+S%22">Sanchez-Roige S</searchLink>; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA.; Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Potenza+M%22">Potenza M</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Wu Tsai Institute, Yale University, New Haven, CT, USA.; Child Study Center, Yale School of Medicine, New Haven, CT, USA.; Connecticut Council on Problem Gambling, Wethersfield, CT, USA.; Connecticut Mental Health Center, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Mutirangura+A%22">Mutirangura A</searchLink>; Department of Anatomy, Faculty of Medicine, https://ror.org/028wp3y58Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Shotelersuk+V%22">Shotelersuk V</searchLink>; Center of Excellence for Medical Genomics, Department of Pediatrics, Faculty of Medicine, https://ror.org/028wp3y58Chulalongkorn University, Bangkok, Thailand.; Excellence Center for Genomics and Precision Medicine, King Chulalongkorn Memorial Hospital, the Thai Red Cross Society, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Kalayasiri+R%22">Kalayasiri R</searchLink>; Department of Psychiatry, Epidemiology of Psychiatric Disorders and Mental Health Research Unit, Faculty of Medicine, https://ror.org/028wp3y58Chulalongkorn University, Bangkok, Thailand.; Department of Psychiatry, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Edenberg+HJ%22">Edenberg HJ</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Gelernter+J%22">Gelernter J</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, CT, USA.; 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      – TitleFull: Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits.
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          Dates:
            – D: 20
              M: 08
              Text: 2025 Aug 20
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1469-8978
          Numbering:
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              Value: 55
          Titles:
            – TitleFull: Psychological medicine
              Type: main
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