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DNA Methylation Biomarkers Predict Offspring Metabolic Risk From Mothers With Hyperglycemia in Pregnancy.

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Title: DNA Methylation Biomarkers Predict Offspring Metabolic Risk From Mothers With Hyperglycemia in Pregnancy.
Authors: Assaf J; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., Khurana I; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Central Clinical School, Department of Diabetes, Monash University, Melbourne, Victoria, Australia.; Baker Department of Cardiometabolic Health, The University of Melbourne, Parkville, Victoria, Australia., Abou Zaki R; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Baker Department of Cardiometabolic Health, The University of Melbourne, Parkville, Victoria, Australia., Tam CHT; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Correa I; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., Maxwell S; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Central Clinical School, Department of Diabetes, Monash University, Melbourne, Victoria, Australia., Kinnberg J; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., Christiansen M; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., Frørup C; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Baker Department of Cardiometabolic Health, The University of Melbourne, Parkville, Victoria, Australia., Lee HM; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Kaipananickal H; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Central Clinical School, Department of Diabetes, Monash University, Melbourne, Victoria, Australia., Okabe J; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., Marikar SN; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., Wong KK; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Lim CKP; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Yuen LY; Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Yang X; Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China., Wang CC; Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Chan JCN; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Yip KYL; Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Sanford Burnham Prebys, La Jolla, CA., Lowe WL Jr; Center for Diabetes and Metabolism, Feinberg School of Medicine, Northwestern University, Chicago, IL., Tam WH; Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China., Ma RCW; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., El-Osta A; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Biomedical Laboratory Science, Faculty of Health, Department of Technology, University College Copenhagen, Copenhagen, Denmark.; Department of Anatomy, Cell Biology, and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
Source: Diabetes [Diabetes] 2025 Sep 01; Vol. 74 (9), pp. 1695-1707.
Publication Type: Journal Article
Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: DNA Methylation Biomarkers Predict Offspring Metabolic Risk From Mothers With Hyperglycemia in Pregnancy.
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  Data: <searchLink fieldCode="AU" term="%22Assaf+J%22">Assaf J</searchLink>; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Khurana+I%22">Khurana I</searchLink>; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Central Clinical School, Department of Diabetes, Monash University, Melbourne, Victoria, Australia.; Baker Department of Cardiometabolic Health, The University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Abou+Zaki+R%22">Abou Zaki R</searchLink>; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Baker Department of Cardiometabolic Health, The University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Tam+CHT%22">Tam CHT</searchLink>; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Correa+I%22">Correa I</searchLink>; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Maxwell+S%22">Maxwell S</searchLink>; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Central Clinical School, Department of Diabetes, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Kinnberg+J%22">Kinnberg J</searchLink>; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Christiansen+M%22">Christiansen M</searchLink>; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Frørup+C%22">Frørup C</searchLink>; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Baker Department of Cardiometabolic Health, The University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Lee+HM%22">Lee HM</searchLink>; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Kaipananickal+H%22">Kaipananickal H</searchLink>; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Central Clinical School, Department of Diabetes, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Okabe+J%22">Okabe J</searchLink>; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Marikar+SN%22">Marikar SN</searchLink>; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Wong+KK%22">Wong KK</searchLink>; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Lim+CKP%22">Lim CKP</searchLink>; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Yuen+LY%22">Yuen LY</searchLink>; Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Wang+CC%22">Wang CC</searchLink>; Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Chan+JCN%22">Chan JCN</searchLink>; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Yip+KYL%22">Yip KYL</searchLink>; Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Sanford Burnham Prebys, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Lowe+WL+Jr%22">Lowe WL Jr</searchLink>; Center for Diabetes and Metabolism, Feinberg School of Medicine, Northwestern University, Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Tam+WH%22">Tam WH</searchLink>; Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Ma+RCW%22">Ma RCW</searchLink>; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22El-Osta+A%22">El-Osta A</searchLink>; Epigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Biomedical Laboratory Science, Faculty of Health, Department of Technology, University College Copenhagen, Copenhagen, Denmark.; Department of Anatomy, Cell Biology, and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Diabetes+Association%22">American Diabetes Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372763 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1939-327X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200121797%22">00121797 </searchLink><i>NLM ISO Abbreviation: </i>Diabetes <i>Subsets: </i>MEDLINE
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