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Acute cannabidiol (CBD), tetrahydrocannabinol (THC) and their mixture (THC:CBD) exert differential effects on brain activity and blood flow in rats: A translational neuroimaging study.

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Title: Acute cannabidiol (CBD), tetrahydrocannabinol (THC) and their mixture (THC:CBD) exert differential effects on brain activity and blood flow in rats: A translational neuroimaging study.
Authors: MacNicol E; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Kokkinou M; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK., Serrano Navacerrada ME; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Smith DM; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK., Li J; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK., Simmons C; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Kim E; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Mesquita M; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; L&M Data Science Ltd., London, UK., Rojo Gonzalez L; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; L&M Data Science Ltd., London, UK., Andrews T; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Loomis S; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK., Gray RA; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK., Knappertz V; Department of Neurology and Psychiatry, Heinrich-Heine University, Düsseldorf, Germany., Whalley BJ; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK.; School of Pharmacy, University of Reading, Reading, Berkshire, UK.; Revelstone Consulting LLC, Washington, DC, USA., McCreary AC; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK., Williams SC; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Virley D; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK., Cash D; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Source: Journal of psychopharmacology (Oxford, England) [J Psychopharmacol] 2026 Mar; Vol. 40 (3), pp. 429-447. Date of Electronic Publication: 2025 Aug 21.
Publication Type: Journal Article
Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 8907828 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1461-7285 (Electronic) Linking ISSN: 02698811 NLM ISO Abbreviation: J Psychopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Acute cannabidiol (CBD), tetrahydrocannabinol (THC) and their mixture (THC:CBD) exert differential effects on brain activity and blood flow in rats: A translational neuroimaging study.
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  Data: <searchLink fieldCode="AU" term="%22MacNicol+E%22">MacNicol E</searchLink>; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kokkinou+M%22">Kokkinou M</searchLink>; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Serrano+Navacerrada+ME%22">Serrano Navacerrada ME</searchLink>; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Smith+DM%22">Smith DM</searchLink>; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Simmons+C%22">Simmons C</searchLink>; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kim+E%22">Kim E</searchLink>; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Mesquita+M%22">Mesquita M</searchLink>; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; L&M Data Science Ltd., London, UK.<br /><searchLink fieldCode="AU" term="%22Rojo+Gonzalez+L%22">Rojo Gonzalez L</searchLink>; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; L&M Data Science Ltd., London, UK.<br /><searchLink fieldCode="AU" term="%22Andrews+T%22">Andrews T</searchLink>; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Loomis+S%22">Loomis S</searchLink>; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Gray+RA%22">Gray RA</searchLink>; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Knappertz+V%22">Knappertz V</searchLink>; Department of Neurology and Psychiatry, Heinrich-Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Whalley+BJ%22">Whalley BJ</searchLink>; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK.; School of Pharmacy, University of Reading, Reading, Berkshire, UK.; Revelstone Consulting LLC, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22McCreary+AC%22">McCreary AC</searchLink>; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Williams+SC%22">Williams SC</searchLink>; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Virley+D%22">Virley D</searchLink>; Jazz Pharmaceuticals Research UK Ltd., Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Cash+D%22">Cash D</searchLink>; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
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  Data: <searchLink fieldCode="JN" term="%228907828%22">Journal of psychopharmacology (Oxford, England)</searchLink> [J Psychopharmacol] 2026 Mar; Vol. 40 (3), pp. 429-447. <i>Date of Electronic Publication: </i>2025 Aug 21.
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      – TitleFull: Acute cannabidiol (CBD), tetrahydrocannabinol (THC) and their mixture (THC:CBD) exert differential effects on brain activity and blood flow in rats: A translational neuroimaging study.
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