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Integrative plasma metabolomic profiling identifies distinct vascular and inflammatory signatures in hospital emergency department patients.

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Title: Integrative plasma metabolomic profiling identifies distinct vascular and inflammatory signatures in hospital emergency department patients.
Authors: Chang JK; Precision Medicine Translational Research Programme and Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; SLING, Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore., Jee Y; Emergency Medicine Department, National University Hospital, National University Health System, Singapore, Singapore., Khaing NW; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Chua MT; Emergency Medicine Department, National University Hospital, National University Health System, Singapore, Singapore; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Choi H; SLING, Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Kuan WS; Emergency Medicine Department, National University Hospital, National University Health System, Singapore, Singapore; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. Electronic address: surkws@nus.edu.sg., Torta F; Precision Medicine Translational Research Programme and Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; SLING, Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore; Signature Research Program in Cardiovascular and Metabolic Disorders, Duke-National University of Singapore Medical School, Singapore. Electronic address: bchfdtt@nus.edu.sg., Wenk MR; Precision Medicine Translational Research Programme and Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar. Electronic address: mwenk@hbku.edu.qa.
Source: Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2026 Jan 01; Vol. 578, pp. 120562. Date of Electronic Publication: 2025 Aug 21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 1302422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3492 (Electronic) Linking ISSN: 00098981 NLM ISO Abbreviation: Clin Chim Acta Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrative plasma metabolomic profiling identifies distinct vascular and inflammatory signatures in hospital emergency department patients.
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  Data: <searchLink fieldCode="AU" term="%22Chang+JK%22">Chang JK</searchLink>; Precision Medicine Translational Research Programme and Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; SLING, Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Jee+Y%22">Jee Y</searchLink>; Emergency Medicine Department, National University Hospital, National University Health System, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Khaing+NW%22">Khaing NW</searchLink>; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chua+MT%22">Chua MT</searchLink>; Emergency Medicine Department, National University Hospital, National University Health System, Singapore, Singapore; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Choi+H%22">Choi H</searchLink>; SLING, Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Kuan+WS%22">Kuan WS</searchLink>; Emergency Medicine Department, National University Hospital, National University Health System, Singapore, Singapore; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. Electronic address: surkws@nus.edu.sg.<br /><searchLink fieldCode="AU" term="%22Torta+F%22">Torta F</searchLink>; Precision Medicine Translational Research Programme and Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; SLING, Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore; Signature Research Program in Cardiovascular and Metabolic Disorders, Duke-National University of Singapore Medical School, Singapore. Electronic address: bchfdtt@nus.edu.sg.<br /><searchLink fieldCode="AU" term="%22Wenk+MR%22">Wenk MR</searchLink>; Precision Medicine Translational Research Programme and Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar. Electronic address: mwenk@hbku.edu.qa.
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  Data: <searchLink fieldCode="JN" term="%221302422%22">Clinica chimica acta; international journal of clinical chemistry</searchLink> [Clin Chim Acta] 2026 Jan 01; Vol. 578, pp. 120562. <i>Date of Electronic Publication: </i>2025 Aug 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>1302422 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-3492 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200098981%22">00098981 </searchLink><i>NLM ISO Abbreviation: </i>Clin Chim Acta <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.cca.2025.120562
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      – Code: eng
        Text: English
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              Text: 2026 Jan 01
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