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Transient gene melting governs the timing of oligodendrocyte maturation.

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Title: Transient gene melting governs the timing of oligodendrocyte maturation.
Authors: Allan KC; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Zhan JJ; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Morton AR; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Cohn EF; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Scavuzzo MA; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Nikhil A; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Elitt MS; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Clayton BLL; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Hu LR; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Shick HE; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Vrabic JK; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Olsen HE; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Factor DC; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Henninger JE; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA., Bachmann G; Ionis Pharmaceuticals, Carlsbad, CA 92010, USA., Powers BE; Ionis Pharmaceuticals, Carlsbad, CA 92010, USA., Young RA; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA., Lin CY; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Scacheri PC; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Miller TE; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Department of Pathology and Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Tesar PJ; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA. Electronic address: paul.tesar@case.edu.
Source: Cell [Cell] 2025 Oct 30; Vol. 188 (22), pp. 6205-6219.e23. Date of Electronic Publication: 2025 Aug 25.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Allan+KC%22">Allan KC</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Zhan+JJ%22">Zhan JJ</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Morton+AR%22">Morton AR</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Cohn+EF%22">Cohn EF</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Scavuzzo+MA%22">Scavuzzo MA</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Nikhil+A%22">Nikhil A</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Elitt+MS%22">Elitt MS</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Clayton+BLL%22">Clayton BLL</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Hu+LR%22">Hu LR</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Shick+HE%22">Shick HE</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Vrabic+JK%22">Vrabic JK</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Olsen+HE%22">Olsen HE</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Factor+DC%22">Factor DC</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Henninger+JE%22">Henninger JE</searchLink>; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Bachmann+G%22">Bachmann G</searchLink>; Ionis Pharmaceuticals, Carlsbad, CA 92010, USA.<br /><searchLink fieldCode="AU" term="%22Powers+BE%22">Powers BE</searchLink>; Ionis Pharmaceuticals, Carlsbad, CA 92010, USA.<br /><searchLink fieldCode="AU" term="%22Young+RA%22">Young RA</searchLink>; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Lin+CY%22">Lin CY</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Scacheri+PC%22">Scacheri PC</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Miller+TE%22">Miller TE</searchLink>; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Department of Pathology and Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Tesar+PJ%22">Tesar PJ</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Institute for Glial Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA. Electronic address: paul.tesar@case.edu.
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  Data: <searchLink fieldCode="JN" term="%220413066%22">Cell</searchLink> [Cell] 2025 Oct 30; Vol. 188 (22), pp. 6205-6219.e23. <i>Date of Electronic Publication: </i>2025 Aug 25.
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