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Pain management beyond opioids: a β-arrestin2-biased allosteric GPCR modulator opens new avenues for drug development.

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Title: Pain management beyond opioids: a β-arrestin2-biased allosteric GPCR modulator opens new avenues for drug development.
Authors: Pottie E; Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium., Steinmüller SAM; School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen Foresterhill, Aberdeen, UK., Decker M; Pharmazeutische und Medizinische Chemie, Institut für Pharmazie und Lebensmittelchemie, Julius-Maximilians-Universität Würzburg (JMU), Würzburg, Germany. michael.decker@uni-wuerzburg.de.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2025 Aug 27; Vol. 10 (1), pp. 264. Date of Electronic Publication: 2025 Aug 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Pottie+E%22">Pottie E</searchLink>; Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Steinmüller+SAM%22">Steinmüller SAM</searchLink>; School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen Foresterhill, Aberdeen, UK.<br /><searchLink fieldCode="AU" term="%22Decker+M%22">Decker M</searchLink>; Pharmazeutische und Medizinische Chemie, Institut für Pharmazie und Lebensmittelchemie, Julius-Maximilians-Universität Würzburg (JMU), Würzburg, Germany. michael.decker@uni-wuerzburg.de.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101676423 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-3635 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220593635%22">20593635 </searchLink><i>NLM ISO Abbreviation: </i>Signal Transduct Target Ther <i>Subsets: </i>MEDLINE; In Process
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      – TitleFull: Pain management beyond opioids: a β-arrestin2-biased allosteric GPCR modulator opens new avenues for drug development.
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              Text: 2025 Aug 27
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