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Blood immunomap for prediction of responses to anti-PD-1 immunotherapy in metastatic non-small cell lung cancer.

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Title: Blood immunomap for prediction of responses to anti-PD-1 immunotherapy in metastatic non-small cell lung cancer.
Authors: Semitekolou M; Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, Medical School, University of Crete, 70013 Heraklion, Greece.; Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.; Dendritic Cells and Adaptive Immunity Unit, Institut Pasteur, CNRS UMR3738 'Developmental Biology and Stem Cells', Institut Pasteur, Paris, France., Paschalidis N; Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece., Lo Tartaro D; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, 41121 Modena, Italy., Tsitsopoulou A; Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece., Stamou P; Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, Medical School, University of Crete, 70013 Heraklion, Greece., Mavroudis A; Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, Medical School, University of Crete, 70013 Heraklion, Greece., Markaki E; Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, Medical School, University of Crete, 70013 Heraklion, Greece., Varveri A; Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, Medical School, University of Crete, 70013 Heraklion, Greece., Morianos I; Host Defense & Fungal Pathogenesis Laboratory, Medical School, University of Crete, 70013 Heraklion, Greece.; Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology - Hellas (FORTH), 70013 Heraklion, Greece., Lavigne M; Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology - Hellas (FORTH), 70013 Heraklion, Greece., Fotsitzoudis C; Laboratory of Translational Oncology, School of Medicine, University of Crete, 70013 Heraklion, Greece., Magkouta S; Department of Critical Care and Pulmonary Medicine, Evangelismos Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece., Dede K; Department of Critical Care and Pulmonary Medicine, Evangelismos Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece., Kalomenidis I; Department of Critical Care and Pulmonary Medicine, Evangelismos Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece., Samitas K; Respiratory Clinic and Asthma Center of the 'Sotiria' Athens Chest Hospital, Athens, Greece., Potaris K; Department of Thoracic Surgery, Athens Chest Hospital 'Sotiria', 11527 Athens, Greece., Cossarizza A; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, 41121 Modena, Italy.; National Institute for Cardiovascular Research, 40126 Bologna, Italy., Mavroudis D; Laboratory of Translational Oncology, School of Medicine, University of Crete, 70013 Heraklion, Greece., De Biasi S; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, 41121 Modena, Italy., Verginis P; Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, Medical School, University of Crete, 70013 Heraklion, Greece.; Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology - Hellas (FORTH), 70013 Heraklion, Greece.
Source: IScience [iScience] 2025 Jun 02; Vol. 28 (9), pp. 112804. Date of Electronic Publication: 2025 Jun 02 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Semitekolou+M%22">Semitekolou M</searchLink>; Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, Medical School, University of Crete, 70013 Heraklion, Greece.; Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.; Dendritic Cells and Adaptive Immunity Unit, Institut Pasteur, CNRS UMR3738 'Developmental Biology and Stem Cells', Institut Pasteur, Paris, France.<br /><searchLink fieldCode="AU" term="%22Paschalidis+N%22">Paschalidis N</searchLink>; Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Lo+Tartaro+D%22">Lo Tartaro D</searchLink>; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, 41121 Modena, Italy.<br /><searchLink fieldCode="AU" term="%22Tsitsopoulou+A%22">Tsitsopoulou A</searchLink>; Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Stamou+P%22">Stamou P</searchLink>; Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, Medical School, University of Crete, 70013 Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22Mavroudis+A%22">Mavroudis A</searchLink>; Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, Medical School, University of Crete, 70013 Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22Markaki+E%22">Markaki E</searchLink>; Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, Medical School, University of Crete, 70013 Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22Varveri+A%22">Varveri A</searchLink>; Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, Medical School, University of Crete, 70013 Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22Morianos+I%22">Morianos I</searchLink>; Host Defense & Fungal Pathogenesis Laboratory, Medical School, University of Crete, 70013 Heraklion, Greece.; Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology - Hellas (FORTH), 70013 Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22Lavigne+M%22">Lavigne M</searchLink>; Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology - Hellas (FORTH), 70013 Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22Fotsitzoudis+C%22">Fotsitzoudis C</searchLink>; Laboratory of Translational Oncology, School of Medicine, University of Crete, 70013 Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22Magkouta+S%22">Magkouta S</searchLink>; Department of Critical Care and Pulmonary Medicine, Evangelismos Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Dede+K%22">Dede K</searchLink>; Department of Critical Care and Pulmonary Medicine, Evangelismos Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Kalomenidis+I%22">Kalomenidis I</searchLink>; Department of Critical Care and Pulmonary Medicine, Evangelismos Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Samitas+K%22">Samitas K</searchLink>; Respiratory Clinic and Asthma Center of the 'Sotiria' Athens Chest Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Potaris+K%22">Potaris K</searchLink>; Department of Thoracic Surgery, Athens Chest Hospital 'Sotiria', 11527 Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Cossarizza+A%22">Cossarizza A</searchLink>; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, 41121 Modena, Italy.; National Institute for Cardiovascular Research, 40126 Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Mavroudis+D%22">Mavroudis D</searchLink>; Laboratory of Translational Oncology, School of Medicine, University of Crete, 70013 Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22De+Biasi+S%22">De Biasi S</searchLink>; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, 41121 Modena, Italy.<br /><searchLink fieldCode="AU" term="%22Verginis+P%22">Verginis P</searchLink>; Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, Medical School, University of Crete, 70013 Heraklion, Greece.; Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology - Hellas (FORTH), 70013 Heraklion, Greece.
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