Temporal metabolomic fingerprinting identifies adenine as a novel biomarker for early detection of Escherichia coli infection in broiler chickens.

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Title: Temporal metabolomic fingerprinting identifies adenine as a novel biomarker for early detection of Escherichia coli infection in broiler chickens.
Authors: Ranaraja A; Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, SK, S7N 5B4, Saskatoon, Canada., Subhasinghe I; Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, SK, S7N 5B4, Saskatoon, Canada., Ahmad SN; Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, SK, S7N 5B4, Saskatoon, Canada., Banaganapalli B; Department of Genetic Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Popowich S; Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, SK, S7N 5B4, Saskatoon, Canada., Parambath SV; Division of Molecular Medicine, St. John's Research Institute, Bangalore, India., Ayalew LE; Department of Pathology and Microbiology, Atlantic Veterinary College, University of Prince Edward Island, 550 University Ave, Charlottetown, PE, C1A 4P3, Canada., Mandal R; Departments of Biological Sciences and Computing Science, University of Alberta, Edmonton, AB, T6G 2E9, Canada., Wishart DS; Departments of Biological Sciences and Computing Science, University of Alberta, Edmonton, AB, T6G 2E9, Canada., Tikoo S; Vaccinology and Immunotherapy, School of Public Health, University of Saskatchewan, Saskatoon, 7 N 5E3, Canada., Gomis S; Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, SK, S7N 5B4, Saskatoon, Canada. susantha.gomis@usask.ca.
Source: Scientific reports [Sci Rep] 2025 Aug 27; Vol. 15 (1), pp. 31580. Date of Electronic Publication: 2025 Aug 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Temporal metabolomic fingerprinting identifies adenine as a novel biomarker for early detection of Escherichia coli infection in broiler chickens.
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  Data: <searchLink fieldCode="AU" term="%22Ranaraja+A%22">Ranaraja A</searchLink>; Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, SK, S7N 5B4, Saskatoon, Canada.<br /><searchLink fieldCode="AU" term="%22Subhasinghe+I%22">Subhasinghe I</searchLink>; Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, SK, S7N 5B4, Saskatoon, Canada.<br /><searchLink fieldCode="AU" term="%22Ahmad+SN%22">Ahmad SN</searchLink>; Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, SK, S7N 5B4, Saskatoon, Canada.<br /><searchLink fieldCode="AU" term="%22Banaganapalli+B%22">Banaganapalli B</searchLink>; Department of Genetic Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Popowich+S%22">Popowich S</searchLink>; Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, SK, S7N 5B4, Saskatoon, Canada.<br /><searchLink fieldCode="AU" term="%22Parambath+SV%22">Parambath SV</searchLink>; Division of Molecular Medicine, St. John's Research Institute, Bangalore, India.<br /><searchLink fieldCode="AU" term="%22Ayalew+LE%22">Ayalew LE</searchLink>; Department of Pathology and Microbiology, Atlantic Veterinary College, University of Prince Edward Island, 550 University Ave, Charlottetown, PE, C1A 4P3, Canada.<br /><searchLink fieldCode="AU" term="%22Mandal+R%22">Mandal R</searchLink>; Departments of Biological Sciences and Computing Science, University of Alberta, Edmonton, AB, T6G 2E9, Canada.<br /><searchLink fieldCode="AU" term="%22Wishart+DS%22">Wishart DS</searchLink>; Departments of Biological Sciences and Computing Science, University of Alberta, Edmonton, AB, T6G 2E9, Canada.<br /><searchLink fieldCode="AU" term="%22Tikoo+S%22">Tikoo S</searchLink>; Vaccinology and Immunotherapy, School of Public Health, University of Saskatchewan, Saskatoon, 7 N 5E3, Canada.<br /><searchLink fieldCode="AU" term="%22Gomis+S%22">Gomis S</searchLink>; Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, SK, S7N 5B4, Saskatoon, Canada. susantha.gomis@usask.ca.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2025 Aug 27; Vol. 15 (1), pp. 31580. <i>Date of Electronic Publication: </i>2025 Aug 27.
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