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Mendelian randomization, lipids, and coronary artery disease: trade-offs between study designs and assumptions.

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Title: Mendelian randomization, lipids, and coronary artery disease: trade-offs between study designs and assumptions.
Authors: Shi J; Division of Population Health and Data Sciences, Massachusetts Veterans Epidemiology Research and Information Collaborative (MAVERIC), VA Boston Healthcare System, Boston, MA, United States.; CAUSALab, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States., Swanson SA; CAUSALab, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, United States., Diemer EW; CAUSALab, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States., Gerlovin H; Division of Population Health and Data Sciences, Massachusetts Veterans Epidemiology Research and Information Collaborative (MAVERIC), VA Boston Healthcare System, Boston, MA, United States., Posner DC; Division of Population Health and Data Sciences, Massachusetts Veterans Epidemiology Research and Information Collaborative (MAVERIC), VA Boston Healthcare System, Boston, MA, United States., Wilson PWF; Department of Medicine, Veteran Affairs Atlanta Healthcare System, Decatur, GA, United States.; Division of Cardiology, Emory University School of Medicine, Atlanta, GA, United States.; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, United States., Gaziano JM; Division of Population Health and Data Sciences, Massachusetts Veterans Epidemiology Research and Information Collaborative (MAVERIC), VA Boston Healthcare System, Boston, MA, United States.; Department of Medicine, Harvard Medical School, Boston, MA, United States.; Department of Medicine, Division of Aging, Brigham and Women's Hospital, Boston, MA, United States., Cho K; Division of Population Health and Data Sciences, Massachusetts Veterans Epidemiology Research and Information Collaborative (MAVERIC), VA Boston Healthcare System, Boston, MA, United States.; Department of Medicine, Harvard Medical School, Boston, MA, United States.; Department of Medicine, Division of Aging, Brigham and Women's Hospital, Boston, MA, United States., Hernán MA; CAUSALab, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
Corporate Authors: VA Million Veteran Program
Source: American journal of epidemiology [Am J Epidemiol] 2025 Dec 02; Vol. 194 (12), pp. 3581-3589.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 7910653 Publication Model: Print Cited Medium: Internet ISSN: 1476-6256 (Electronic) Linking ISSN: 00029262 NLM ISO Abbreviation: Am J Epidemiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Shi+J%22">Shi J</searchLink>; Division of Population Health and Data Sciences, Massachusetts Veterans Epidemiology Research and Information Collaborative (MAVERIC), VA Boston Healthcare System, Boston, MA, United States.; CAUSALab, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Swanson+SA%22">Swanson SA</searchLink>; CAUSALab, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Diemer+EW%22">Diemer EW</searchLink>; CAUSALab, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Gerlovin+H%22">Gerlovin H</searchLink>; Division of Population Health and Data Sciences, Massachusetts Veterans Epidemiology Research and Information Collaborative (MAVERIC), VA Boston Healthcare System, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Posner+DC%22">Posner DC</searchLink>; Division of Population Health and Data Sciences, Massachusetts Veterans Epidemiology Research and Information Collaborative (MAVERIC), VA Boston Healthcare System, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Wilson+PWF%22">Wilson PWF</searchLink>; Department of Medicine, Veteran Affairs Atlanta Healthcare System, Decatur, GA, United States.; Division of Cardiology, Emory University School of Medicine, Atlanta, GA, United States.; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, United States.<br /><searchLink fieldCode="AU" term="%22Gaziano+JM%22">Gaziano JM</searchLink>; Division of Population Health and Data Sciences, Massachusetts Veterans Epidemiology Research and Information Collaborative (MAVERIC), VA Boston Healthcare System, Boston, MA, United States.; Department of Medicine, Harvard Medical School, Boston, MA, United States.; Department of Medicine, Division of Aging, Brigham and Women's Hospital, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Cho+K%22">Cho K</searchLink>; Division of Population Health and Data Sciences, Massachusetts Veterans Epidemiology Research and Information Collaborative (MAVERIC), VA Boston Healthcare System, Boston, MA, United States.; Department of Medicine, Harvard Medical School, Boston, MA, United States.; Department of Medicine, Division of Aging, Brigham and Women's Hospital, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Hernán+MA%22">Hernán MA</searchLink>; CAUSALab, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
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        Value: 10.1093/aje/kwaf190
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              Text: 2025 Dec 02
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