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Mesenchymal stem cells suppress NF-κB and ERK signalling while enhancing chemotaxis in CD4+ T cells.

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Title: Mesenchymal stem cells suppress NF-κB and ERK signalling while enhancing chemotaxis in CD4+ T cells.
Authors: Sengun E; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands. ezgi.sengun@radboudumc.nl., Fröberg J; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands., He X; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands., Eleveld M; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands., Smeets RL; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands., Koenen HJPM; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands., Möller-Hackbarth K; Global Rare Disease, Chiesi Pharma AB, 17165, Solna, Sweden., Wolfs TGAM; Department of Paediatrics, MosaKids Children's Hospital, Maastricht University Medical Centre+, Maastricht, The Netherlands.; GROW, School for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands., Ophelders DRMG; Department of Paediatrics, MosaKids Children's Hospital, Maastricht University Medical Centre+, Maastricht, The Netherlands.; GROW, School for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands., Huynen MA; Center for Molecular and Biomolecular Informatics, Radboud University Medical Centre Nijmegen, Radboud University for Molecular Life Sciences, Nijmegen, 6525 GA, The Netherlands., de Jonge MI; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands., van der Molen RG; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands.
Source: Scientific reports [Sci Rep] 2025 Aug 30; Vol. 15 (1), pp. 32000. Date of Electronic Publication: 2025 Aug 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mesenchymal stem cells suppress NF-κB and ERK signalling while enhancing chemotaxis in CD4<superscript>+</superscript> T cells.
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  Data: <searchLink fieldCode="AU" term="%22Sengun+E%22">Sengun E</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands. ezgi.sengun@radboudumc.nl.<br /><searchLink fieldCode="AU" term="%22Fröberg+J%22">Fröberg J</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22He+X%22">He X</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Eleveld+M%22">Eleveld M</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Smeets+RL%22">Smeets RL</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Koenen+HJPM%22">Koenen HJPM</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Möller-Hackbarth+K%22">Möller-Hackbarth K</searchLink>; Global Rare Disease, Chiesi Pharma AB, 17165, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Wolfs+TGAM%22">Wolfs TGAM</searchLink>; Department of Paediatrics, MosaKids Children's Hospital, Maastricht University Medical Centre+, Maastricht, The Netherlands.; GROW, School for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ophelders+DRMG%22">Ophelders DRMG</searchLink>; Department of Paediatrics, MosaKids Children's Hospital, Maastricht University Medical Centre+, Maastricht, The Netherlands.; GROW, School for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Huynen+MA%22">Huynen MA</searchLink>; Center for Molecular and Biomolecular Informatics, Radboud University Medical Centre Nijmegen, Radboud University for Molecular Life Sciences, Nijmegen, 6525 GA, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Jonge+MI%22">de Jonge MI</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Molen+RG%22">van der Molen RG</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Route 469, Geert Grooteplein 10, PO-Box 9101, 6500 HB, Nijmegen, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2025 Aug 30; Vol. 15 (1), pp. 32000. <i>Date of Electronic Publication: </i>2025 Aug 30.
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