Neutrophil-specific targeting of STAT3 impairs tumor progression via the expansion of cytotoxic CD8+ T cells.
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| Title: | Neutrophil-specific targeting of STAT3 impairs tumor progression via the expansion of cytotoxic CD8+ T cells. |
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| Authors: | Ozel I; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Essen, Essen, University of Duisburg-Essen, Essen, 45147, Germany., Sha G; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Essen, Essen, University of Duisburg-Essen, Essen, 45147, Germany., Będzińska A; Center for Translational Research and Molecular Biology of Cancer, Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice, 44101, Poland., Pylaeva E; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Essen, Essen, University of Duisburg-Essen, Essen, 45147, Germany., Naumova Y; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Essen, Essen, University of Duisburg-Essen, Essen, 45147, Germany., Thiel I; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Essen, Essen, University of Duisburg-Essen, Essen, 45147, Germany., Antczak J; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Essen, Essen, University of Duisburg-Essen, Essen, 45147, Germany., Squire A; Institute for Experimental Immunology and Imaging, University Hospital Essen, University of Duisburg-Essen, Essen, 45141, Germany., Gunzer M; Institute for Experimental Immunology and Imaging, University Hospital Essen, University of Duisburg-Essen, Essen, 45141, Germany., Zelinskyy G; Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, 45147, Germany., Kürten C; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Essen, Essen, University of Duisburg-Essen, Essen, 45147, Germany., Lang S; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Essen, Essen, University of Duisburg-Essen, Essen, 45147, Germany.; German Cancer Consortium (DKTK) partner site Düsseldorf/Essen, Essen, 45147, Germany., Silvestre-Roig C; Institute of Experimental Pathology (ExPat), Center for Molecular Biology of Inflammation (ZMBE), University of Münster, Münster, 48149, Germany., Kortylewski M; Department of Immuno-Oncology, Beckman Research Institute at City of Hope Comprehensive Cancer Center, Duarte, CA, 91010, USA.; Center for Gene Therapy, Beckman Research Institute at City of Hope Comprehensive Cancer Center, Duarte, CA, 91010, USA., Granot Z; Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel Canada, Faculty of Medicine, Hebrew University, Jerusalem, 91120, Israel., Jablonska J; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Essen, Essen, University of Duisburg-Essen, Essen, 45147, Germany. jadwiga.jablonska@uk-essen.de.; German Cancer Consortium (DKTK) partner site Düsseldorf/Essen, Essen, 45147, Germany. jadwiga.jablonska@uk-essen.de. |
| Source: | Signal transduction and targeted therapy [Signal Transduct Target Ther] 2025 Aug 30; Vol. 10 (1), pp. 279. Date of Electronic Publication: 2025 Aug 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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