Single-molecule fluorescence microscopy reveals regulatory mechanisms of MYO7A-driven cargo transport in stereocilia of live inner ear hair cells.

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Title: Single-molecule fluorescence microscopy reveals regulatory mechanisms of MYO7A-driven cargo transport in stereocilia of live inner ear hair cells.
Authors: Miyoshi T; Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA. tmiyoshi26@siumed.edu.; Division of Molecular and Integrative Physiology, Department of Biomedical Sciences, Southern Illinois University School of Medicine, Carbondale, IL, USA. tmiyoshi26@siumed.edu., Vishwasrao HD; Advanced Imaging and Microscopy Resource, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USA., Belyantseva IA; Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA., Miyoshi J; Division of Molecular and Integrative Physiology, Department of Biomedical Sciences, Southern Illinois University School of Medicine, Carbondale, IL, USA., Sajeevadathan M; Division of Molecular and Integrative Physiology, Department of Biomedical Sciences, Southern Illinois University School of Medicine, Carbondale, IL, USA., Ishibashi Y; Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA.; Inner Ear Gene Therapy Program, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA., Adadey SM; Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA., Harada N; Hearing Research Laboratory, Harada ENT Clinic, Higashi-Osaka, Osaka, Japan., Shroff H; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA., Friedman TB; Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA.
Source: Nature communications [Nat Commun] 2025 Sep 01; Vol. 16 (1), pp. 8149. Date of Electronic Publication: 2025 Sep 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Single-molecule fluorescence microscopy reveals regulatory mechanisms of MYO7A-driven cargo transport in stereocilia of live inner ear hair cells.
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  Data: <searchLink fieldCode="AU" term="%22Miyoshi+T%22">Miyoshi T</searchLink>; Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA. tmiyoshi26@siumed.edu.; Division of Molecular and Integrative Physiology, Department of Biomedical Sciences, Southern Illinois University School of Medicine, Carbondale, IL, USA. tmiyoshi26@siumed.edu.<br /><searchLink fieldCode="AU" term="%22Vishwasrao+HD%22">Vishwasrao HD</searchLink>; Advanced Imaging and Microscopy Resource, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Belyantseva+IA%22">Belyantseva IA</searchLink>; Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Miyoshi+J%22">Miyoshi J</searchLink>; Division of Molecular and Integrative Physiology, Department of Biomedical Sciences, Southern Illinois University School of Medicine, Carbondale, IL, USA.<br /><searchLink fieldCode="AU" term="%22Sajeevadathan+M%22">Sajeevadathan M</searchLink>; Division of Molecular and Integrative Physiology, Department of Biomedical Sciences, Southern Illinois University School of Medicine, Carbondale, IL, USA.<br /><searchLink fieldCode="AU" term="%22Ishibashi+Y%22">Ishibashi Y</searchLink>; Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA.; Inner Ear Gene Therapy Program, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Adadey+SM%22">Adadey SM</searchLink>; Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Harada+N%22">Harada N</searchLink>; Hearing Research Laboratory, Harada ENT Clinic, Higashi-Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Shroff+H%22">Shroff H</searchLink>; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.<br /><searchLink fieldCode="AU" term="%22Friedman+TB%22">Friedman TB</searchLink>; Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Sep 01; Vol. 16 (1), pp. 8149. <i>Date of Electronic Publication: </i>2025 Sep 01.
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              Text: 2025 Sep 01
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