MDS-associated SF3B1 mutations promote aberrant fate choice of hematopoietic stem cell via mis-splicing of mediator kinase module component CDK8.

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Title: MDS-associated SF3B1 mutations promote aberrant fate choice of hematopoietic stem cell via mis-splicing of mediator kinase module component CDK8.
Authors: Bonner EA, Hsueh TY, Song A, Arriaga-Gomez EA, Venkataraman R, Sinha S, Nguyen E, Ferrell PB, Welner RS, Lu R, Stirewalt DL, Doulatov S, Lee SC
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Aug 19. Date of Electronic Publication: 2025 Aug 19.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40894548
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: MDS-associated SF3B1 mutations promote aberrant fate choice of hematopoietic stem cell via mis-splicing of mediator kinase module component CDK8.
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  Data: <searchLink fieldCode="AU" term="%22Bonner+EA%22">Bonner EA</searchLink><br /><searchLink fieldCode="AU" term="%22Hsueh+TY%22">Hsueh TY</searchLink><br /><searchLink fieldCode="AU" term="%22Song+A%22">Song A</searchLink><br /><searchLink fieldCode="AU" term="%22Arriaga-Gomez+EA%22">Arriaga-Gomez EA</searchLink><br /><searchLink fieldCode="AU" term="%22Venkataraman+R%22">Venkataraman R</searchLink><br /><searchLink fieldCode="AU" term="%22Sinha+S%22">Sinha S</searchLink><br /><searchLink fieldCode="AU" term="%22Nguyen+E%22">Nguyen E</searchLink><br /><searchLink fieldCode="AU" term="%22Ferrell+PB%22">Ferrell PB</searchLink><br /><searchLink fieldCode="AU" term="%22Welner+RS%22">Welner RS</searchLink><br /><searchLink fieldCode="AU" term="%22Lu+R%22">Lu R</searchLink><br /><searchLink fieldCode="AU" term="%22Stirewalt+DL%22">Stirewalt DL</searchLink><br /><searchLink fieldCode="AU" term="%22Doulatov+S%22">Doulatov S</searchLink><br /><searchLink fieldCode="AU" term="%22Lee+SC%22">Lee SC</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Aug 19. <i>Date of Electronic Publication: </i>2025 Aug 19.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40894548
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      – Type: doi
        Value: 10.1101/2025.08.14.670174
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      – Code: eng
        Text: English
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      – TitleFull: MDS-associated SF3B1 mutations promote aberrant fate choice of hematopoietic stem cell via mis-splicing of mediator kinase module component CDK8.
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            NameFull: Bonner EA
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            – D: 19
              M: 08
              Text: 2025 Aug 19
              Type: published
              Y: 2025
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