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Persistent Immune Dysregulation during Post-Acute Sequelae of COVID-19 is Manifested in Antibodies Targeting Envelope and Nucleocapsid Proteins.

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Title: Persistent Immune Dysregulation during Post-Acute Sequelae of COVID-19 is Manifested in Antibodies Targeting Envelope and Nucleocapsid Proteins.
Authors: Kwissa M; Department of Biochemistry and Molecular Genetics, University of Illinois, College of Medicine, Chicago, IL, USA.; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL., Mathayan M; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Department of Microbiology and Immunology, University of Illinois, College of Medicine, Chicago, IL, USA., Salunkhe SS; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Department of Microbiology and Immunology, University of Illinois, College of Medicine, Chicago, IL, USA., Bakthavachalam V; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Department of Microbiology and Immunology, University of Illinois, College of Medicine, Chicago, IL, USA., Ye Z; Department of Biochemistry and Molecular Genetics, University of Illinois, College of Medicine, Chicago, IL, USA.; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL., Sanborn MA; Department of Biochemistry and Molecular Genetics, University of Illinois, College of Medicine, Chicago, IL, USA.; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL., Condo S; Department of Biochemistry and Molecular Genetics, University of Illinois, College of Medicine, Chicago, IL, USA.; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL., Upadhye A; Department of Biochemistry and Molecular Genetics, University of Illinois, College of Medicine, Chicago, IL, USA.; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL., Nemakal A; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Research Resources Center, University of Illinois at Chicago, Chicago, IL, USA., Richner JM; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Department of Microbiology and Immunology, University of Illinois, College of Medicine, Chicago, IL, USA., Basu S; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois Chicago, Chicago, IL, USA., Novak RM; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Division of Infectious Disease, Department of Medicine, University of Illinois, College of Medicine, Chicago, IL, USA., Jacobson JR; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Division of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois, College of Medicine, Chicago, IL, USA., Ganesh BB; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Research Resources Center, University of Illinois at Chicago, Chicago, IL, USA., Cerda M; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Patient Representative, RECOVER, ASI Home Care, Chicago, IL, USA., Utz PJ; Division of Immunology and Rheumatology, Department of Medicine, Stanford, CA.; Stanford Institute for Immunity, Transplantation and Infection., Krishnan JA; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Division of Infectious Disease, Department of Medicine, University of Illinois, College of Medicine, Chicago, IL, USA., Prabhakar BS; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Department of Microbiology and Immunology, University of Illinois, College of Medicine, Chicago, IL, USA., Rehman J; Department of Biochemistry and Molecular Genetics, University of Illinois, College of Medicine, Chicago, IL, USA.; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; University of Illinois Cancer Center, Chicago, IL, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Aug 19. Date of Electronic Publication: 2025 Aug 19.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Persistent Immune Dysregulation during Post-Acute Sequelae of COVID-19 is Manifested in Antibodies Targeting Envelope and Nucleocapsid Proteins.
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  Data: <searchLink fieldCode="AU" term="%22Kwissa+M%22">Kwissa M</searchLink>; Department of Biochemistry and Molecular Genetics, University of Illinois, College of Medicine, Chicago, IL, USA.; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Mathayan+M%22">Mathayan M</searchLink>; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Department of Microbiology and Immunology, University of Illinois, College of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Salunkhe+SS%22">Salunkhe SS</searchLink>; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Department of Microbiology and Immunology, University of Illinois, College of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Bakthavachalam+V%22">Bakthavachalam V</searchLink>; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Department of Microbiology and Immunology, University of Illinois, College of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Ye+Z%22">Ye Z</searchLink>; Department of Biochemistry and Molecular Genetics, University of Illinois, College of Medicine, Chicago, IL, USA.; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Sanborn+MA%22">Sanborn MA</searchLink>; Department of Biochemistry and Molecular Genetics, University of Illinois, College of Medicine, Chicago, IL, USA.; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Condo+S%22">Condo S</searchLink>; Department of Biochemistry and Molecular Genetics, University of Illinois, College of Medicine, Chicago, IL, USA.; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Upadhye+A%22">Upadhye A</searchLink>; Department of Biochemistry and Molecular Genetics, University of Illinois, College of Medicine, Chicago, IL, USA.; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Nemakal+A%22">Nemakal A</searchLink>; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Research Resources Center, University of Illinois at Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Richner+JM%22">Richner JM</searchLink>; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Department of Microbiology and Immunology, University of Illinois, College of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Basu+S%22">Basu S</searchLink>; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Novak+RM%22">Novak RM</searchLink>; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Division of Infectious Disease, Department of Medicine, University of Illinois, College of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Jacobson+JR%22">Jacobson JR</searchLink>; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Division of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois, College of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Ganesh+BB%22">Ganesh BB</searchLink>; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Research Resources Center, University of Illinois at Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Cerda+M%22">Cerda M</searchLink>; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Patient Representative, RECOVER, ASI Home Care, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Utz+PJ%22">Utz PJ</searchLink>; Division of Immunology and Rheumatology, Department of Medicine, Stanford, CA.; Stanford Institute for Immunity, Transplantation and Infection.<br /><searchLink fieldCode="AU" term="%22Krishnan+JA%22">Krishnan JA</searchLink>; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Division of Infectious Disease, Department of Medicine, University of Illinois, College of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Prabhakar+BS%22">Prabhakar BS</searchLink>; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; Department of Microbiology and Immunology, University of Illinois, College of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Rehman+J%22">Rehman J</searchLink>; Department of Biochemistry and Molecular Genetics, University of Illinois, College of Medicine, Chicago, IL, USA.; Illinois Research Network (ILLInet) RECOVER Hub, Chicago, IL.; University of Illinois Cancer Center, Chicago, IL, USA.
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