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Clonal haematopoiesis of indeterminate potential and mortality in coronary artery disease.

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Title: Clonal haematopoiesis of indeterminate potential and mortality in coronary artery disease.
Authors: von Scheidt M; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Adkar SS; Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Krefting J; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Hoermann G; MLL Munich Leukemia Laboratory, Munich, Germany., Meggendorfer M; MLL Munich Leukemia Laboratory, Munich, Germany., Bauer S; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Mitchell S; Department of Pathology, Stanford University, Stanford, CA, USA., Pugach I; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Friess C; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Ma A; Department of Genetics and Genomic Sciences, Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hao K; Department of Genetics and Genomic Sciences, Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Steigerwald S; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Wahle M; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Kessler T; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Schwab M; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Voll F; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany., Mokry M; Laboratory of Experimental Cardiology, Department of Cardiology, University Medical Center Utrecht, University Utrecht, Utrecht, Netherlands.; Central Diagnostics Laboratory, University Medical Center Utrecht, Utrecht, Netherlands., Sofokleous C; Central Diagnostics Laboratory, University Medical Center Utrecht, Utrecht, Netherlands., Palm KCA; Central Diagnostics Laboratory, University Medical Center Utrecht, Utrecht, Netherlands., Bongiovanni D; Department of Internal Medicine I, Cardiology, University Hospital Augsburg, University of Augsburg, Augsburg, Germany.; Department of Cardiovascular Medicine, Humanitas Clinical and Research Center IRCCS, Humanitas University, Rozzano, Milan, Italy., Fleig J; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany., Oldenbuettel L; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany., Chen Z; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Hecker JS; Department of Medicine III, TUM Klinikum Rechts der Isar, Munich, Germany and TranslaTUM, Center for Translational Cancer Research, Technical University of Munich (TUM), Munich, Germany., Bassermann F; Department of Medicine III, TUM Klinikum Rechts der Isar, Munich, Germany and TranslaTUM, Center for Translational Cancer Research, Technical University of Munich (TUM), Munich, Germany., Maegdefessel L; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.; Institute of Molecular Vascular Medicine, TUM Klinikum Rechts der Isar, Technical University Munich, Munich, Germany., Graw M; Institute of Legal Medicine, Faculty of Medicine, LMU Munich, Munich, Germany., Ruusalepp A; Department of Cardiac Surgery, The Heart Clinic, Tartu University Hospital, Tartu, Estonia.; Clinical Gene Networks AB, Stockholm, Sweden.; Institute of Clinical Medicine, Faculty of Medicine, Tartu University, Tartu, Estonia., Hilgendorf I; Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, University of Freiburg, Freiburg, Germany., Leuschner F; Department of Medicine III, University of Heidelberg, German Centre for Cardiovascular Research (DZHK), Heidelberg, Germany., Sager HB; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Heimlich JB; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Koenig W; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Cremer S; Department of Cardiology, Goethe University Frankfurt, Frankfurt am Main, Germany., Leistner DM; Department of Cardiology, Goethe University Frankfurt, Frankfurt am Main, Germany., Abplanalp WT; Institute for Cardiovascular Regeneration, Goethe University Frankfurt am Main, Frankfurt am Main, Germany., Dimmeler S; Institute for Cardiovascular Regeneration, Goethe University Frankfurt am Main, Frankfurt am Main, Germany., Zeiher AM; Department of Cardiology, Goethe University Frankfurt, Frankfurt am Main, Germany.; Institute for Cardiovascular Regeneration, Goethe University Frankfurt am Main, Frankfurt am Main, Germany., van der Laan SW; Laboratory of Experimental Cardiology, Department of Cardiology, University Medical Center Utrecht, University Utrecht, Utrecht, Netherlands.; Central Diagnostics Laboratory, University Medical Center Utrecht, Utrecht, Netherlands., Pasterkamp G; Laboratory of Experimental Cardiology, Department of Cardiology, University Medical Center Utrecht, University Utrecht, Utrecht, Netherlands.; Central Diagnostics Laboratory, University Medical Center Utrecht, Utrecht, Netherlands., Braun C; Institute of Legal Medicine, Faculty of Medicine, LMU Munich, Munich, Germany., Jaiswal S; Department of Pathology, Stanford University, Stanford, CA, USA., Kovacic JC; Victor Chang Cardiac Research Institute, Darlinghurst, Australia.; St. Vincent's Clinical School, University of New South Wales, Sydney, Australia.; Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kern W; MLL Munich Leukemia Laboratory, Munich, Germany., Haferlach C; MLL Munich Leukemia Laboratory, Munich, Germany., Mann M; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Cassese S; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany., Kastrati A; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Haferlach T; MLL Munich Leukemia Laboratory, Munich, Germany., Leeper NJ; Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA., Björkegren JLM; Department of Genetics and Genomic Sciences, Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Clinical Gene Networks AB, Stockholm, Sweden.; Department of Medicine, Huddinge, Karolinska Institutet, Karolinska Universitetssjukhuset, Stockholm, Sweden., Schunkert H; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.
Source: European heart journal [Eur Heart J] 2026 Jan 24; Vol. 47 (4), pp. 453-469.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8006263 Publication Model: Print Cited Medium: Internet ISSN: 1522-9645 (Electronic) Linking ISSN: 0195668X NLM ISO Abbreviation: Eur Heart J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22von+Scheidt+M%22">von Scheidt M</searchLink>; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Adkar+SS%22">Adkar SS</searchLink>; Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Krefting+J%22">Krefting J</searchLink>; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hoermann+G%22">Hoermann G</searchLink>; MLL Munich Leukemia Laboratory, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Meggendorfer+M%22">Meggendorfer M</searchLink>; MLL Munich Leukemia Laboratory, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Bauer+S%22">Bauer S</searchLink>; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Mitchell+S%22">Mitchell S</searchLink>; Department of Pathology, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pugach+I%22">Pugach I</searchLink>; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Friess+C%22">Friess C</searchLink>; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ma+A%22">Ma A</searchLink>; Department of Genetics and Genomic Sciences, Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hao+K%22">Hao K</searchLink>; Department of Genetics and Genomic Sciences, Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Steigerwald+S%22">Steigerwald S</searchLink>; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Wahle+M%22">Wahle M</searchLink>; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Kessler+T%22">Kessler T</searchLink>; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schwab+M%22">Schwab M</searchLink>; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Voll+F%22">Voll F</searchLink>; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.<br /><searchLink fieldCode="AU" term="%22Mokry+M%22">Mokry M</searchLink>; Laboratory of Experimental Cardiology, Department of Cardiology, University Medical Center Utrecht, University Utrecht, Utrecht, Netherlands.; Central Diagnostics Laboratory, University Medical Center Utrecht, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Sofokleous+C%22">Sofokleous C</searchLink>; 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Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hecker+JS%22">Hecker JS</searchLink>; Department of Medicine III, TUM Klinikum Rechts der Isar, Munich, Germany and TranslaTUM, Center for Translational Cancer Research, Technical University of Munich (TUM), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Bassermann+F%22">Bassermann F</searchLink>; Department of Medicine III, TUM Klinikum Rechts der Isar, Munich, Germany and TranslaTUM, Center for Translational Cancer Research, Technical University of Munich (TUM), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Maegdefessel+L%22">Maegdefessel L</searchLink>; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.; Institute of Molecular Vascular Medicine, TUM Klinikum Rechts der Isar, Technical University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Graw+M%22">Graw M</searchLink>; 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Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Heimlich+JB%22">Heimlich JB</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Koenig+W%22">Koenig W</searchLink>; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Cremer+S%22">Cremer S</searchLink>; Department of Cardiology, Goethe University Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Leistner+DM%22">Leistner DM</searchLink>; Department of Cardiology, Goethe University Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Abplanalp+WT%22">Abplanalp WT</searchLink>; 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Central Diagnostics Laboratory, University Medical Center Utrecht, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Braun+C%22">Braun C</searchLink>; Institute of Legal Medicine, Faculty of Medicine, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Jaiswal+S%22">Jaiswal S</searchLink>; Department of Pathology, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kovacic+JC%22">Kovacic JC</searchLink>; Victor Chang Cardiac Research Institute, Darlinghurst, Australia.; St. Vincent's Clinical School, University of New South Wales, Sydney, Australia.; Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kern+W%22">Kern W</searchLink>; MLL Munich Leukemia Laboratory, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Haferlach+C%22">Haferlach C</searchLink>; MLL Munich Leukemia Laboratory, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Mann+M%22">Mann M</searchLink>; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Cassese+S%22">Cassese S</searchLink>; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.<br /><searchLink fieldCode="AU" term="%22Kastrati+A%22">Kastrati A</searchLink>; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Haferlach+T%22">Haferlach T</searchLink>; MLL Munich Leukemia Laboratory, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Leeper+NJ%22">Leeper NJ</searchLink>; Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Björkegren+JLM%22">Björkegren JLM</searchLink>; Department of Genetics and Genomic Sciences, Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Clinical Gene Networks AB, Stockholm, Sweden.; Department of Medicine, Huddinge, Karolinska Institutet, Karolinska Universitetssjukhuset, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Schunkert+H%22">Schunkert H</searchLink>; Department of Cardiology, TUM Klinikum Deutsches Herzzentrum, Technical University Munich, Lazarettstr. 36, Munich D-80636, Germany.; Deutsches Zentrum für Herz- und Kreislaufforschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.
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          Name:
            NameFull: Sager HB
      – PersonEntity:
          Name:
            NameFull: Heimlich JB
      – PersonEntity:
          Name:
            NameFull: Koenig W
      – PersonEntity:
          Name:
            NameFull: Cremer S
      – PersonEntity:
          Name:
            NameFull: Leistner DM
      – PersonEntity:
          Name:
            NameFull: Abplanalp WT
      – PersonEntity:
          Name:
            NameFull: Dimmeler S
      – PersonEntity:
          Name:
            NameFull: Zeiher AM
      – PersonEntity:
          Name:
            NameFull: van der Laan SW
      – PersonEntity:
          Name:
            NameFull: Pasterkamp G
      – PersonEntity:
          Name:
            NameFull: Braun C
      – PersonEntity:
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            NameFull: Jaiswal S
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            NameFull: Kovacic JC
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            NameFull: Kern W
      – PersonEntity:
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            NameFull: Haferlach C
      – PersonEntity:
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            NameFull: Mann M
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            NameFull: Haferlach T
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          Name:
            NameFull: Leeper NJ
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          Name:
            NameFull: Björkegren JLM
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            NameFull: Schunkert H
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 24
              M: 01
              Text: 2026 Jan 24
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1522-9645
          Numbering:
            – Type: volume
              Value: 47
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: European heart journal
              Type: main
ResultId 1