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A human-mouse atlas of intrarenal myeloid cells identifies conserved disease-associated macrophages in lupus nephritis.

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Title: A human-mouse atlas of intrarenal myeloid cells identifies conserved disease-associated macrophages in lupus nephritis.
Authors: Hoover PJ; Division of Rheumatology, Inflammation and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; The Broad Institute of MIT and Harvard , Cambridge, MA, USA., Raparia C; Institute of Molecular Medicine, Feinstein Institutes for Medical Research , Manhasset, NY, USA., Lieb DJ; The Broad Institute of MIT and Harvard , Cambridge, MA, USA., Tzur Y; Rappaport Faculty of Medicine, Technion - Israel Institute of Technology , Haifa, Israel., Kang J; Center for Data Sciences, Brigham and Women's Hospital , Boston, MA, USA.; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard , Cambridge, MA, USA., Arazi A; Institute of Molecular Medicine, Feinstein Institutes for Medical Research , Manhasset, NY, USA., Leavitt R; The Broad Institute of MIT and Harvard , Cambridge, MA, USA., Mishra R; Institute of Molecular Medicine, Feinstein Institutes for Medical Research , Manhasset, NY, USA., Shah SI; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Simmons D; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Li S; The Broad Institute of MIT and Harvard , Cambridge, MA, USA., Peters M; The Broad Institute of MIT and Harvard , Cambridge, MA, USA., Eisenhaure T; The Broad Institute of MIT and Harvard , Cambridge, MA, USA., Few-Cooper TJ; Rappaport Faculty of Medicine, Technion - Israel Institute of Technology , Haifa, Israel., Gurajala SS; Center for Data Sciences, Brigham and Women's Hospital , Boston, MA, USA.; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard , Cambridge, MA, USA., Sonny A; The Broad Institute of MIT and Harvard , Cambridge, MA, USA., Hodgin JB; Department of Pathology, University of Michigan, Ann Arbor, Ann Arbor, Michigan, USA., Berthier CC; Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA., Guthridge JM; Department of Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Fava A; Division of Rheumatology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., Clancy RM; Division of Rheumatology, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA., Putterman C; Division of Rheumatology and Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.; Azrieli Faculty of Medicine, Bar-Ilan University , Zefat, Israel., Izmirly PM; Division of Rheumatology, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA., Belmont HM; Division of Rheumatology, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA., Kalunian K; Division of Rheumatology, Autoimmunity and Inflammation, University of California, San Diego School of Medicine, San Diego, CA, USA., Kamen D; Department of Medicine, Medical University of South Carolina, Charleston, SC, USA., Wofsy D; Rheumatology Division, Department of Medicine, Russell/Engleman Rheumatology Research Center, University of California San Francisco, San Francisco, CA, USA., Buyon JP; Department of Pathology, University of Michigan, Ann Arbor, Ann Arbor, Michigan, USA., James JA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard , Cambridge, MA, USA., Petri M; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Diamond B; Institute of Molecular Medicine, Feinstein Institutes for Medical Research , Manhasset, NY, USA., Raychaudhuri S; Division of Rheumatology, Inflammation and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; The Broad Institute of MIT and Harvard , Cambridge, MA, USA.; Center for Data Sciences, Brigham and Women's Hospital , Boston, MA, USA.; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard , Cambridge, MA, USA., Shen-Orr SS; Rappaport Faculty of Medicine, Technion - Israel Institute of Technology , Haifa, Israel., Hacohen N; The Broad Institute of MIT and Harvard , Cambridge, MA, USA.; Massachusetts General Hospital, Krantz Family Center for Cancer Research , Boston, MA, USA., Davidson A; Institute of Molecular Medicine, Feinstein Institutes for Medical Research , Manhasset, NY, USA.
Corporate Authors: Accelerating Medicines Partnership in RA/SLE network
Source: The Journal of experimental medicine [J Exp Med] 2025 Nov 03; Vol. 222 (11). Date of Electronic Publication: 2025 Sep 03.
Publication Type: Journal Article
Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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Rheumatology Division, Department of Medicine, Russell/Engleman Rheumatology Research Center, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Buyon+JP%22">Buyon JP</searchLink>; Department of Pathology, University of Michigan, Ann Arbor, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22James+JA%22">James JA</searchLink>; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard , Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Petri+M%22">Petri M</searchLink>; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Diamond+B%22">Diamond B</searchLink>; Institute of Molecular Medicine, Feinstein Institutes for Medical Research , Manhasset, NY, USA.<br /><searchLink fieldCode="AU" term="%22Raychaudhuri+S%22">Raychaudhuri S</searchLink>; Division of Rheumatology, Inflammation and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; The Broad Institute of MIT and Harvard , Cambridge, MA, USA.; Center for Data Sciences, Brigham and Women's Hospital , Boston, MA, USA.; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard , Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Shen-Orr+SS%22">Shen-Orr SS</searchLink>; Rappaport Faculty of Medicine, Technion - Israel Institute of Technology , Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Hacohen+N%22">Hacohen N</searchLink>; The Broad Institute of MIT and Harvard , Cambridge, MA, USA.; Massachusetts General Hospital, Krantz Family Center for Cancer Research , Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Davidson+A%22">Davidson A</searchLink>; Institute of Molecular Medicine, Feinstein Institutes for Medical Research , Manhasset, NY, USA.
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