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Transdermal radiofrequency (V ERASER®) plus polidocanol sclerotherapy versus polidocanol sclerotherapy alone for the treatment of reticular veins and telangiectasias. A randomized controlled trial (TYPER trial).

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Title: Transdermal radiofrequency (V ERASER®) plus polidocanol sclerotherapy versus polidocanol sclerotherapy alone for the treatment of reticular veins and telangiectasias. A randomized controlled trial (TYPER trial).
Authors: Higino Becker R; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil., Caffaro RA; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil., de Oliveira CCC; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil., Marcondes RP; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil., Negrão AR; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil., Magella F; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil., Volpiani GG; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil., Neves S; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil., Rodrigues RCB; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.; Vascular Surgery Department, Centro Universitário São Lucas Ji-Paraná, Rondônia, Brazil., Rodrigues MFBF; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.; Vascular Surgery Department, Universidade do Rio Grande - FURG, Rio Grande, Rio Grande do Sul, Brazil., da Silva VS; Clinical Trials Department, Science Valley Research Institute, São Paulo, Brazil., Ribeiro CM; Clinical Trials Department, Science Valley Research Institute, São Paulo, Brazil., Kikuchi R; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil., Santiago FR; Vascular Surgery Department, Universidade Federal de Goiás, Goiânia, Brazil., Ramacciotti E; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.; Clinical Trials Department, Science Valley Research Institute, São Paulo, Brazil.; Haemostasis & Thrombosis Research Laboratories, Loyola University Medical Centre, Maywood, IL, USA.
Source: Phlebology [Phlebology] 2026 Jun; Vol. 41 (5), pp. 410-418. Date of Electronic Publication: 2025 Sep 04.
Publication Type: Journal Article; Randomized Controlled Trial; Comparative Study
Journal Info: Publisher: Sage Country of Publication: England NLM ID: 9012921 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1758-1125 (Electronic) Linking ISSN: 02683555 NLM ISO Abbreviation: Phlebology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Transdermal radiofrequency (V ERASER®) plus polidocanol sclerotherapy versus polidocanol sclerotherapy alone for the treatment of reticular veins and telangiectasias. A randomized controlled trial (TYPER trial).
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  Data: <searchLink fieldCode="AU" term="%22Higino+Becker+R%22">Higino Becker R</searchLink>; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Caffaro+RA%22">Caffaro RA</searchLink>; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Oliveira+CCC%22">de Oliveira CCC</searchLink>; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Marcondes+RP%22">Marcondes RP</searchLink>; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Negrão+AR%22">Negrão AR</searchLink>; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Magella+F%22">Magella F</searchLink>; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Volpiani+GG%22">Volpiani GG</searchLink>; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Neves+S%22">Neves S</searchLink>; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Rodrigues+RCB%22">Rodrigues RCB</searchLink>; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.; Vascular Surgery Department, Centro Universitário São Lucas Ji-Paraná, Rondônia, Brazil.<br /><searchLink fieldCode="AU" term="%22Rodrigues+MFBF%22">Rodrigues MFBF</searchLink>; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.; Vascular Surgery Department, Universidade do Rio Grande - FURG, Rio Grande, Rio Grande do Sul, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+VS%22">da Silva VS</searchLink>; Clinical Trials Department, Science Valley Research Institute, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Ribeiro+CM%22">Ribeiro CM</searchLink>; Clinical Trials Department, Science Valley Research Institute, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Kikuchi+R%22">Kikuchi R</searchLink>; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Santiago+FR%22">Santiago FR</searchLink>; Vascular Surgery Department, Universidade Federal de Goiás, Goiânia, Brazil.<br /><searchLink fieldCode="AU" term="%22Ramacciotti+E%22">Ramacciotti E</searchLink>; Vascular Surgery Department, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.; Clinical Trials Department, Science Valley Research Institute, São Paulo, Brazil.; Haemostasis & Thrombosis Research Laboratories, Loyola University Medical Centre, Maywood, IL, USA.
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  Data: <searchLink fieldCode="JN" term="%229012921%22">Phlebology</searchLink> [Phlebology] 2026 Jun; Vol. 41 (5), pp. 410-418. <i>Date of Electronic Publication: </i>2025 Sep 04.
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  Data: Journal Article; Randomized Controlled Trial; Comparative Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Sage%22">Sage </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9012921 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1758-1125 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202683555%22">02683555 </searchLink><i>NLM ISO Abbreviation: </i>Phlebology <i>Subsets: </i>MEDLINE
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      – TitleFull: Transdermal radiofrequency (V ERASER®) plus polidocanol sclerotherapy versus polidocanol sclerotherapy alone for the treatment of reticular veins and telangiectasias. A randomized controlled trial (TYPER trial).
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              Text: 2026 Jun
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