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Spatial colocalization and molecular crosstalk of myofibroblastic CAFs and tumor cells shape lymph node metastasis in oral squamous cell carcinoma.

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Title: Spatial colocalization and molecular crosstalk of myofibroblastic CAFs and tumor cells shape lymph node metastasis in oral squamous cell carcinoma.
Authors: Furudate K; Department of Oral and Maxillofacial Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.; Department of Medical Data Intelligence, Research Center for Health-Medical Data Science, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.; Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America., Kasai S; Department of Stress Response Science, Biomedical Research Center, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Yoshizawa T; Department of Anatomic Pathology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Sasaki Y; Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.; Department of Hematology, University of Tsukuba Hospital, Tsukuba, Japan., Fujikura K; Department of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe, Japan., Goto S; Department of Anatomic Pathology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Ito R; Department of Oral and Maxillofacial Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Takagi K; Department of Oral and Maxillofacial Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Tanaka T; Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America., Kijima H; Department of Anatomic Pathology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Kubota K; Department of Oral and Maxillofacial Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Itoh K; Department of Stress Response Science, Biomedical Research Center, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Kobayashi W; Department of Oral and Maxillofacial Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Takahashi K; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.; Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Source: PLoS genetics [PLoS Genet] 2025 Sep 04; Vol. 21 (9), pp. e1011791. Date of Electronic Publication: 2025 Sep 04 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Spatial colocalization and molecular crosstalk of myofibroblastic CAFs and tumor cells shape lymph node metastasis in oral squamous cell carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Furudate+K%22">Furudate K</searchLink>; Department of Oral and Maxillofacial Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.; Department of Medical Data Intelligence, Research Center for Health-Medical Data Science, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.; Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Kasai+S%22">Kasai S</searchLink>; Department of Stress Response Science, Biomedical Research Center, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshizawa+T%22">Yoshizawa T</searchLink>; Department of Anatomic Pathology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.<br /><searchLink fieldCode="AU" term="%22Sasaki+Y%22">Sasaki Y</searchLink>; Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.; Department of Hematology, University of Tsukuba Hospital, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Fujikura+K%22">Fujikura K</searchLink>; Department of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Goto+S%22">Goto S</searchLink>; Department of Anatomic Pathology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+R%22">Ito R</searchLink>; Department of Oral and Maxillofacial Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.<br /><searchLink fieldCode="AU" term="%22Takagi+K%22">Takagi K</searchLink>; Department of Oral and Maxillofacial Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.<br /><searchLink fieldCode="AU" term="%22Tanaka+T%22">Tanaka T</searchLink>; Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Kijima+H%22">Kijima H</searchLink>; Department of Anatomic Pathology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.<br /><searchLink fieldCode="AU" term="%22Kubota+K%22">Kubota K</searchLink>; Department of Oral and Maxillofacial Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.<br /><searchLink fieldCode="AU" term="%22Itoh+K%22">Itoh K</searchLink>; Department of Stress Response Science, Biomedical Research Center, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.<br /><searchLink fieldCode="AU" term="%22Kobayashi+W%22">Kobayashi W</searchLink>; Department of Oral and Maxillofacial Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+K%22">Takahashi K</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.; Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
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              Text: 2025 Sep 04
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