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Combining evidence from human genetic and functional screens to identify pathways altering obesity and fat distribution.

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Title: Combining evidence from human genetic and functional screens to identify pathways altering obesity and fat distribution.
Authors: Baya NA; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address: nikolasbaya@gmail.com., Sur Erdem I; Nuffield Department of Women's and Reproductive Health, Medical Sciences Division, University of Oxford, Oxford, UK; Chinese Academy for Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Venkatesh SS; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Reibe S; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK; Nuffield Department of Population Health, Medical Sciences Division, University of Oxford, Oxford, UK., Charles PD; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK., Navarro-Guerrero E; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Hill B; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK; Nuffield Department of Population Health, Medical Sciences Division, University of Oxford, Oxford, UK., Lassen FH; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Claussnitzer M; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Broad Institute of MIT and Harvard, Novo Nordisk Foundation Center for Genomic, Mechanisms of Disease & Type 2 Diabetes Systems Genomics Initiative, Cambridge, MA, USA; Center for Genomic Medicine and Endocrine Division, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Harvard University, Boston, MA, USA., Palmer DS; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK; Nuffield Department of Population Health, Medical Sciences Division, University of Oxford, Oxford, UK; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lindgren CM; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Nuffield Department of Women's and Reproductive Health, Medical Sciences Division, University of Oxford, Oxford, UK; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address: cecilia.m.lindgren@gmail.com.
Source: American journal of human genetics [Am J Hum Genet] 2025 Oct 02; Vol. 112 (10), pp. 2316-2337. Date of Electronic Publication: 2025 Sep 04.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Combining evidence from human genetic and functional screens to identify pathways altering obesity and fat distribution.
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  Data: <searchLink fieldCode="AU" term="%22Baya+NA%22">Baya NA</searchLink>; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address: nikolasbaya@gmail.com.<br /><searchLink fieldCode="AU" term="%22Sur+Erdem+I%22">Sur Erdem I</searchLink>; Nuffield Department of Women's and Reproductive Health, Medical Sciences Division, University of Oxford, Oxford, UK; Chinese Academy for Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Venkatesh+SS%22">Venkatesh SS</searchLink>; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Reibe+S%22">Reibe S</searchLink>; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK; Nuffield Department of Population Health, Medical Sciences Division, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Charles+PD%22">Charles PD</searchLink>; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Navarro-Guerrero+E%22">Navarro-Guerrero E</searchLink>; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Hill+B%22">Hill B</searchLink>; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK; Nuffield Department of Population Health, Medical Sciences Division, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Lassen+FH%22">Lassen FH</searchLink>; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Claussnitzer+M%22">Claussnitzer M</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Broad Institute of MIT and Harvard, Novo Nordisk Foundation Center for Genomic, Mechanisms of Disease & Type 2 Diabetes Systems Genomics Initiative, Cambridge, MA, USA; Center for Genomic Medicine and Endocrine Division, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Harvard University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Palmer+DS%22">Palmer DS</searchLink>; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK; Nuffield Department of Population Health, Medical Sciences Division, University of Oxford, Oxford, UK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lindgren+CM%22">Lindgren CM</searchLink>; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Nuffield Department of Women's and Reproductive Health, Medical Sciences Division, University of Oxford, Oxford, UK; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address: cecilia.m.lindgren@gmail.com.
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        Value: 10.1016/j.ajhg.2025.08.013
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              Text: 2025 Oct 02
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