ADSL deficiency is a secondary mitochondrial disease affecting organelle homeostasis and ERK2/AKT signaling in a linear genotype-phenotype relation. - Bordi M; Testa B; Compagnucci C; Colasuonno F; Cipressa F; Betterini E; Mancini A; Carsetti C; Salvatori I; Ferraina C; Yang M; De Cegli R; et al. (Cell reports, 2025)