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B cell dysregulation during acute COVID-19 is transient.

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Title: B cell dysregulation during acute COVID-19 is transient.
Authors: Jokiranta ST; Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland. Electronic address: suvi.jokiranta@helsinki.fi., Nguyen Ngoc A; Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Huang X; Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Nowlan K; Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Hannolainen L; Department of Virology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Pyöriä L; Department of Virology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Pekkarinen PT; Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Division of Intensive Care Medicine, Department of Anaesthesiology and Intensive Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Dürnsteiner P; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Lääveri T; Infectious Diseases, Inflammation Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Aalto University, Department of Computer Science, School of Science, Espoo, Finland., Heikkilä N; Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Heinonen S; New Children's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Laakso SM; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Department of Neurology, HUS Brain Center, Helsinki University Hospital, Helsinki, Finland., Kantele A; Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Meilahti Infectious Diseases and Vaccine Research Center, MeiVac, Department of Infectious Diseases, University of Helsinki, Helsinki, Finland., Vapalahti O; Department of Virology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Viral Zoonoses Research Unit, Department of Virology, Medicum, University of Helsinki, Helsinki, Finland; Department of Veterinary Biosciences, University of Helsinki, Helsinki, Finland; HUS Diagnostic Center, Clinical Microbiology, Helsinki University Hospital, Helsinki, Finland., Strandin T; Viral Zoonoses Research Unit, Department of Virology, Medicum, University of Helsinki, Helsinki, Finland., Hepojoki J; Department of Virology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Viral Zoonoses Research Unit, Department of Virology, Medicum, University of Helsinki, Helsinki, Finland; University of Zürich, Vetsuisse Faculty, Institute of Veterinary Pathology, Zürich, Switzerland., Perdomo MF; Department of Virology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Kekäläinen E; Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland; HUS Diagnostic Center, Clinical Microbiology, Helsinki University Hospital, Helsinki, Finland.
Source: Immunology letters [Immunol Lett] 2026 Feb; Vol. 277, pp. 107086. Date of Electronic Publication: 2025 Sep 05.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7910006 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0542 (Electronic) Linking ISSN: 01652478 NLM ISO Abbreviation: Immunol Lett Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Jokiranta+ST%22">Jokiranta ST</searchLink>; Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland. Electronic address: suvi.jokiranta@helsinki.fi.<br /><searchLink fieldCode="AU" term="%22Nguyen+Ngoc+A%22">Nguyen Ngoc A</searchLink>; Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Huang+X%22">Huang X</searchLink>; Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Nowlan+K%22">Nowlan K</searchLink>; Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Hannolainen+L%22">Hannolainen L</searchLink>; Department of Virology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Pyöriä+L%22">Pyöriä L</searchLink>; Department of Virology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Pekkarinen+PT%22">Pekkarinen PT</searchLink>; Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Division of Intensive Care Medicine, Department of Anaesthesiology and Intensive Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Dürnsteiner+P%22">Dürnsteiner P</searchLink>; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Lääveri+T%22">Lääveri T</searchLink>; Infectious Diseases, Inflammation Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Aalto University, Department of Computer Science, School of Science, Espoo, Finland.<br /><searchLink fieldCode="AU" term="%22Heikkilä+N%22">Heikkilä N</searchLink>; Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Heinonen+S%22">Heinonen S</searchLink>; New Children's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Laakso+SM%22">Laakso SM</searchLink>; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Department of Neurology, HUS Brain Center, Helsinki University Hospital, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Kantele+A%22">Kantele A</searchLink>; Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Meilahti Infectious Diseases and Vaccine Research Center, MeiVac, Department of Infectious Diseases, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Vapalahti+O%22">Vapalahti O</searchLink>; Department of Virology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Viral Zoonoses Research Unit, Department of Virology, Medicum, University of Helsinki, Helsinki, Finland; Department of Veterinary Biosciences, University of Helsinki, Helsinki, Finland; HUS Diagnostic Center, Clinical Microbiology, Helsinki University Hospital, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Strandin+T%22">Strandin T</searchLink>; Viral Zoonoses Research Unit, Department of Virology, Medicum, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Hepojoki+J%22">Hepojoki J</searchLink>; Department of Virology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Viral Zoonoses Research Unit, Department of Virology, Medicum, University of Helsinki, Helsinki, Finland; University of Zürich, Vetsuisse Faculty, Institute of Veterinary Pathology, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Perdomo+MF%22">Perdomo MF</searchLink>; Department of Virology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Kekäläinen+E%22">Kekäläinen E</searchLink>; Department of Bacteriology and Immunology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland; HUS Diagnostic Center, Clinical Microbiology, Helsinki University Hospital, Helsinki, Finland.
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