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Molecular impact of NOTCH signaling dysregulation on ovarian cancer progression, chemoresistance, and taxane response.

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Title: Molecular impact of NOTCH signaling dysregulation on ovarian cancer progression, chemoresistance, and taxane response.
Authors: Koucka K; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic., Spalenkova A; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic., Seborova K; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic., Tesarova T; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic., Ehrlichova M; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic., Krus I; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic., Holy P; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic., Rob L; Department of Gynecology and Obstetrics, Third Faculty of Medicine and University Hospital Kralovske Vinohrady, Prague, Czech Republic., Hruda M; Department of Gynecology and Obstetrics, Third Faculty of Medicine and University Hospital Kralovske Vinohrady, Prague, Czech Republic., Bouda J; Department of Gynecology and Obstetrics, University Hospital in Pilsen, Charles University, Pilsen, Czech Republic., Bartakova A; Department of Gynecology and Obstetrics, University Hospital in Pilsen, Charles University, Pilsen, Czech Republic., Smoligova V; Department of Gynecology and Obstetrics, University Hospital in Pilsen, Charles University, Pilsen, Czech Republic., Ojima I; Institute of Chemical Biology & Drug Discovery, State University of New York at Stony Brook, Stony Brook, NY, United States., Chen L; Institute of Chemical Biology & Drug Discovery, State University of New York at Stony Brook, Stony Brook, NY, United States., Bendale H; Institute of Chemical Biology & Drug Discovery, State University of New York at Stony Brook, Stony Brook, NY, United States., Mrhalova M; Department of Pathology and Molecular Medicine, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic., Kopeckova K; Department of Oncology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic., Soucek P; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic., Vaclavikova R; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic. Electronic address: radka.vaclavikova@szu.gov.cz.
Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 Oct; Vol. 191, pp. 118532. Date of Electronic Publication: 2025 Sep 08.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE
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  Data: Molecular impact of NOTCH signaling dysregulation on ovarian cancer progression, chemoresistance, and taxane response.
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  Data: <searchLink fieldCode="AU" term="%22Koucka+K%22">Koucka K</searchLink>; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Spalenkova+A%22">Spalenkova A</searchLink>; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Seborova+K%22">Seborova K</searchLink>; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Tesarova+T%22">Tesarova T</searchLink>; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Ehrlichova+M%22">Ehrlichova M</searchLink>; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Krus+I%22">Krus I</searchLink>; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Holy+P%22">Holy P</searchLink>; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Rob+L%22">Rob L</searchLink>; Department of Gynecology and Obstetrics, Third Faculty of Medicine and University Hospital Kralovske Vinohrady, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Hruda+M%22">Hruda M</searchLink>; Department of Gynecology and Obstetrics, Third Faculty of Medicine and University Hospital Kralovske Vinohrady, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Bouda+J%22">Bouda J</searchLink>; Department of Gynecology and Obstetrics, University Hospital in Pilsen, Charles University, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Bartakova+A%22">Bartakova A</searchLink>; Department of Gynecology and Obstetrics, University Hospital in Pilsen, Charles University, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Smoligova+V%22">Smoligova V</searchLink>; Department of Gynecology and Obstetrics, University Hospital in Pilsen, Charles University, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Ojima+I%22">Ojima I</searchLink>; Institute of Chemical Biology & Drug Discovery, State University of New York at Stony Brook, Stony Brook, NY, United States.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Institute of Chemical Biology & Drug Discovery, State University of New York at Stony Brook, Stony Brook, NY, United States.<br /><searchLink fieldCode="AU" term="%22Bendale+H%22">Bendale H</searchLink>; Institute of Chemical Biology & Drug Discovery, State University of New York at Stony Brook, Stony Brook, NY, United States.<br /><searchLink fieldCode="AU" term="%22Mrhalova+M%22">Mrhalova M</searchLink>; Department of Pathology and Molecular Medicine, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Kopeckova+K%22">Kopeckova K</searchLink>; Department of Oncology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Soucek+P%22">Soucek P</searchLink>; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Vaclavikova+R%22">Vaclavikova R</searchLink>; Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic; Laboratory of Pharmacogenomics, Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic. Electronic address: radka.vaclavikova@szu.gov.cz.
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  Data: <searchLink fieldCode="JN" term="%228213295%22">Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie</searchLink> [Biomed Pharmacother] 2025 Oct; Vol. 191, pp. 118532. <i>Date of Electronic Publication: </i>2025 Sep 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Scientifiques+Elsevier%22">Editions Scientifiques Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>8213295 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1950-6007 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207533322%22">07533322 </searchLink><i>NLM ISO Abbreviation: </i>Biomed Pharmacother <i>Subsets: </i>MEDLINE
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